CH459209A - Verfahren zur Herstellung von Phthalimidoacetylverbindungen - Google Patents

Verfahren zur Herstellung von Phthalimidoacetylverbindungen

Info

Publication number
CH459209A
CH459209A CH1156267A CH1156267A CH459209A CH 459209 A CH459209 A CH 459209A CH 1156267 A CH1156267 A CH 1156267A CH 1156267 A CH1156267 A CH 1156267A CH 459209 A CH459209 A CH 459209A
Authority
CH
Switzerland
Prior art keywords
phthalimidoacetyl
compounds
preparation
phthalimidoacetyl compounds
Prior art date
Application number
CH1156267A
Other languages
English (en)
Inventor
Hager Mcmillan Freeman
Pattison Ian
Original Assignee
Warner Lambert Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US262221A external-priority patent/US3192199A/en
Application filed by Warner Lambert Pharmaceutical filed Critical Warner Lambert Pharmaceutical
Publication of CH459209A publication Critical patent/CH459209A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C07D243/32Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing a phthalimide or hydrogenated phthalimide ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1156267A 1963-03-01 1964-02-28 Verfahren zur Herstellung von Phthalimidoacetylverbindungen CH459209A (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US262221A US3192199A (en) 1963-03-01 1963-03-01 Process for the production of 1-cycloalkyl derivatives of 1, 4-benzodiazepine
US427079A US3284503A (en) 1963-03-01 1965-01-21 2-cycloalkylmethylamino-benzhydrols and benzophenones
US427141A US3304313A (en) 1963-03-01 1965-01-21 2-(nu-phthalimidoacetyl-nu-cycloalkylmethyl)-aminobenzophenone derivatives

Publications (1)

Publication Number Publication Date
CH459209A true CH459209A (de) 1968-07-15

Family

ID=27401492

Family Applications (3)

Application Number Title Priority Date Filing Date
CH1156267A CH459209A (de) 1963-03-01 1964-02-28 Verfahren zur Herstellung von Phthalimidoacetylverbindungen
CH1156367A CH466272A (de) 1963-03-01 1964-02-28 Verfahren zur Herstellung von Cycloalkylmethylaminobenzophenonen
CH249064A CH446357A (de) 1963-03-01 1964-02-28 Verfahren zur Herstellung von substituierten 1,4 Benzodiazepinverbindungen

Family Applications After (2)

Application Number Title Priority Date Filing Date
CH1156367A CH466272A (de) 1963-03-01 1964-02-28 Verfahren zur Herstellung von Cycloalkylmethylaminobenzophenonen
CH249064A CH446357A (de) 1963-03-01 1964-02-28 Verfahren zur Herstellung von substituierten 1,4 Benzodiazepinverbindungen

Country Status (9)

Country Link
US (2) US3284503A (de)
BE (1) BE644425A (de)
BR (1) BR6457222D0 (de)
CH (3) CH459209A (de)
DE (1) DE1229098B (de)
DK (5) DK116511B (de)
FR (1) FR1394287A (de)
GB (2) GB1040162A (de)
SE (4) SE320376B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3925364A (en) * 1967-09-22 1975-12-09 Sumitomo Chemical Co Benzodiazepine derivatives
US3549623A (en) * 1968-11-14 1970-12-22 Warner Lambert Pharmaceutical 7-r1-1-(r2)-3-hydroxy-5-phenyl-1h-1,4-benzodiazepin-2(3h)-one
US3691157A (en) * 1970-08-12 1972-09-12 Rodney Ian Fryer Preparation of 7-substituted-1-(2-diethylaminoethyl)-5-(2-halophenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-ones
US4008223A (en) * 1971-12-09 1977-02-15 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler 6-Aza-3H-1,4-benzodiazepines
USRE31071E (en) * 1971-12-09 1982-11-02 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler 6-Aza-3H-1,4-benzodiazepines
KR900003529B1 (ko) * 1985-07-29 1990-05-21 오르토 파마슈티컬 코포레이션 2-아실-3,4-디알콕시아닐린의 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2993062A (en) * 1959-10-22 1961-07-18 Dow Chemical Co Carboxamides of nu-pentachlorophenylethylenediamine
US3153093A (en) * 1961-11-22 1964-10-13 Abbott Lab Amino derivatives of nu-cyclopropylbenzylamines
US3152179A (en) * 1963-03-22 1964-10-06 Searle & Co 2-(hydroxy/oxy)-nu, nu-di (lower alkyl)-5-(6-methoxy-2-naphthyl) cyclopentane-acetamides and congeners

Also Published As

Publication number Publication date
DK128891B (da) 1974-07-22
US3284503A (en) 1966-11-08
CH466272A (de) 1968-12-15
SE326179B (de) 1970-07-20
US3304313A (en) 1967-02-14
DE1229098B (de) 1966-11-24
SE326177B (de) 1970-07-20
FR1394287A (fr) 1965-04-02
DK116511B (da) 1970-01-19
BE644425A (de) 1964-06-27
DK129001B (da) 1974-08-05
GB1040162A (en) 1966-08-24
CH446357A (de) 1967-11-15
DK129003B (da) 1974-08-05
SE326178B (de) 1970-07-20
GB1040163A (en) 1966-08-24
SE320376B (de) 1970-02-09
DK117069B (da) 1970-03-16
BR6457222D0 (pt) 1973-07-17

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