CH206360A - Process for the preparation of a nitrogen compound. - Google Patents

Process for the preparation of a nitrogen compound.

Info

Publication number
CH206360A
CH206360A CH206360DA CH206360A CH 206360 A CH206360 A CH 206360A CH 206360D A CH206360D A CH 206360DA CH 206360 A CH206360 A CH 206360A
Authority
CH
Switzerland
Prior art keywords
preparation
nitrogen compound
hours
rhodanide
amide
Prior art date
Application number
Other languages
German (de)
Inventor
A-G J R Geigy
Original Assignee
Geigy Ag J R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geigy Ag J R filed Critical Geigy Ag J R
Publication of CH206360A publication Critical patent/CH206360A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/02Thiocyanates
    • C07C331/12Thiocyanates having sulfur atoms of thiocyanate groups bound to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

  

  Verfahren zur Darstellung einer Stickstoffverbindung.    Gegenstand des vorliegenden Patentes ist  ein Verfahren zur Darstellung einer Stick  stoffverbindung, dadurch gekennzeichnet, dass  man     Dimethylaminoessigsäure-3',4'-dichlor-          phenylätherphenyl-4-amid    mit a,     ss-Chlor-          äthylenrhodanid    umsetzt. Das Endprodukt,  ein helles, in Wasser lösliches Pulver, hat  gute     fungizide    und bakterizide Eigenschaften  und kann als Desinfektionsmittel verwendet  werden.  



  <I>Beispiel:</I>  17 Teile     Dimethylaminoessigsäure-3',4'-          dichlorphenylätherphenyl-4-amid,    dargestellt  durch Kondensation von 1     Mol        4-Nitrochlor-          benzol    mit 1,2     Mol        3,4-Dichlorphenol    bei       130-1400        durch        Zutropfen        einer        50        %igen     Kalilauge innert 2-4 Stunden, Erhitzen wäh  rend weiteren 4-5 Stunden auf 150-1600,  Reduktion der erhaltenen Nitroverbindung in  bekannter Weise,

   Umsetzung des Amins mit       Chloracetylchlorid    und Erhitzen des Reaktions  produktes unter     gutem    Rühren mit 20     0%iger            Dimethylaminlösung    zuerst 6 Stunden bei  Zimmertemperatur, dann 12-14 Stunden  bei 70-80 0, werden in 50 Teilen Benzol  gelöst und mit 6 Teilen a,     R-Chloräthylen-          rhodanid    zur Reaktion gebracht. Nach     24-          stündigem    Erhitzen unter     Rückfluss    wird mit  viel Äther gefällt und zur Reinigung noch  mals aus Benzol umgefällt.

   Man entfernt die  Lösungsmittel im Vakuum bei 40-50' und  erhält eine schaumig aufgetriebene Substanz,  zerkleinert ein helles Pulver, das in heissem  Wasser opaleszierend löslich ist.



  Process for the preparation of a nitrogen compound. The subject of the present patent is a process for the preparation of a stick material compound, characterized in that dimethylaminoacetic acid 3 ', 4'-dichloro-phenyletherphenyl-4-amide is reacted with α, ß-chloroethylene rhodanide. The final product, a light-colored, water-soluble powder, has good fungicidal and bactericidal properties and can be used as a disinfectant.



  <I> Example: </I> 17 parts of dimethylaminoacetic acid 3 ', 4'-dichlorophenyletherphenyl-4-amide, prepared by condensation of 1 mol of 4-nitrochlorobenzene with 1.2 mol of 3,4-dichlorophenol at 130-1400 by adding dropwise a 50% potassium hydroxide solution within 2-4 hours, heating during a further 4-5 hours to 150-1600, reduction of the nitro compound obtained in a known manner,

   Reaction of the amine with chloroacetyl chloride and heating the reaction product with thorough stirring with 20 0% dimethylamine solution first 6 hours at room temperature, then 12-14 hours at 70-80 0, are dissolved in 50 parts of benzene and 6 parts of a, R- Chlorethylene rhodanide brought to reaction. After heating under reflux for 24 hours, it is precipitated with plenty of ether and reprecipitated from benzene for purification.

   The solvent is removed in vacuo at 40-50 'and a foamy substance is obtained, a light-colored powder which is opalescent soluble in hot water.

 

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung einer Stickstoff verbindung, dadurch gekennzeichnet, dass man Dimetbylaminoessigsäure-3',4'- dichlorphenyl- ätherphenyl-4-amid mit a"p-Chloräthylen- rhodanid umsetzt. Das Endprodukt, ein helles, in Wasser lösliches Pulver, hat gute fungizide und bakterizide Eigenschaften und kann als Desinfektionsmittel verwendet werden. PATENT CLAIM: Process for the preparation of a nitrogen compound, characterized in that dimethylaminoacetic acid-3 ', 4'-dichlorophenyl-etherphenyl-4-amide is reacted with a "p-chloroethylene rhodanide. The end product, a light, water-soluble powder, has good fungicidal and bactericidal properties and can be used as a disinfectant.
CH206360D 1937-12-27 1937-12-27 Process for the preparation of a nitrogen compound. CH206360A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH723275X 1937-12-27
CH206360T 1937-12-27

Publications (1)

Publication Number Publication Date
CH206360A true CH206360A (en) 1939-07-31

Family

ID=25724288

Family Applications (1)

Application Number Title Priority Date Filing Date
CH206360D CH206360A (en) 1937-12-27 1937-12-27 Process for the preparation of a nitrogen compound.

Country Status (1)

Country Link
CH (1) CH206360A (en)

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