CA999236A - Process for producing 4-hydroxymethyl-1-keto-1, 2-dlhydrophthalazine and acid salts thereof, and pharmaceutical composition containing the same - Google Patents

Process for producing 4-hydroxymethyl-1-keto-1, 2-dlhydrophthalazine and acid salts thereof, and pharmaceutical composition containing the same

Info

Publication number
CA999236A
CA999236A CA148,813A CA148813A CA999236A CA 999236 A CA999236 A CA 999236A CA 148813 A CA148813 A CA 148813A CA 999236 A CA999236 A CA 999236A
Authority
CA
Canada
Prior art keywords
dlhydrophthalazine
keto
hydroxymethyl
producing
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA148,813A
Other languages
English (en)
Other versions
CA148813S (en
Inventor
Michiro Inoue
Masayuki Ishikawa
Takashi Tsuchiya
Takio Shimamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of CA999236A publication Critical patent/CA999236A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Cosmetics (AREA)
CA148,813A 1971-08-05 1972-08-04 Process for producing 4-hydroxymethyl-1-keto-1, 2-dlhydrophthalazine and acid salts thereof, and pharmaceutical composition containing the same Expired CA999236A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP46058643A JPS5116430B2 (es) 1971-08-05 1971-08-05

Publications (1)

Publication Number Publication Date
CA999236A true CA999236A (en) 1976-11-02

Family

ID=13090247

Family Applications (2)

Application Number Title Priority Date Filing Date
CA148,812A Expired CA966489A (en) 1971-08-05 1972-08-04 Phthalazone derivatives and process for their manufacture
CA148,813A Expired CA999236A (en) 1971-08-05 1972-08-04 Process for producing 4-hydroxymethyl-1-keto-1, 2-dlhydrophthalazine and acid salts thereof, and pharmaceutical composition containing the same

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA148,812A Expired CA966489A (en) 1971-08-05 1972-08-04 Phthalazone derivatives and process for their manufacture

Country Status (23)

Country Link
US (1) US3864343A (es)
JP (1) JPS5116430B2 (es)
AR (3) AR197089A1 (es)
AT (2) AT317233B (es)
AU (2) AU461281B2 (es)
BE (2) BE787139A (es)
CA (2) CA966489A (es)
CH (2) CH580081A5 (es)
CS (2) CS180587B2 (es)
DE (2) DE2237832A1 (es)
DK (2) DK131857C (es)
ES (2) ES405456A1 (es)
FR (2) FR2150735B1 (es)
GB (2) GB1404367A (es)
HU (2) HU165815B (es)
IE (2) IE36598B1 (es)
LU (2) LU65856A1 (es)
NL (2) NL7210369A (es)
NO (1) NO134113C (es)
SE (2) SE408177B (es)
SU (2) SU577986A3 (es)
YU (1) YU35245B (es)
ZA (2) ZA725203B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205004A1 (es) * 1973-10-30 1976-03-31 Ishikawa M Procedimiento para preparar derivados de 6,8-dialquil-7-alcoxi-carbonil-4-hidroximetil-1-ftalazona y la 7,8-lactona
NL7702763A (nl) * 1976-03-18 1977-09-20 Takio Shimamoto En Masayuki Is Werkwijze voor de bereiding van thromboxaan- -antagonisten en van preparaten die deze stof- fen bevatten.
IE47592B1 (en) * 1977-12-29 1984-05-02 Ici Ltd Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture
US4293553A (en) * 1978-08-11 1981-10-06 Masayuki Ishikawa 1-Phthalazone derivatives, and use thereof
US4861778A (en) * 1986-06-16 1989-08-29 Research Corporation 2,3-dihydrophthalazine-1,4-diones
CH683965A5 (it) * 1993-02-19 1994-06-30 Limad Marketing Exp & Imp Composti della classe dei ftalidrazidici come sostanza attiva in agenti antinfiammatori ed antitossici.
DE102005011822A1 (de) * 2005-03-15 2006-09-21 Merck Patent Gmbh Phthalazinone

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE687916A (es) * 1965-10-12 1967-03-16

Also Published As

Publication number Publication date
HU163726B (es) 1973-10-27
IE36597B1 (en) 1976-12-08
AU461018B2 (en) 1975-05-15
CH580081A5 (es) 1976-09-30
NL7210369A (es) 1973-02-07
BE787138A (fr) 1972-12-01
SE408177B (sv) 1979-05-21
DK143159B (da) 1981-07-06
FR2150735A1 (es) 1973-04-13
AU4494072A (en) 1974-01-31
ZA725203B (en) 1973-04-25
AR197089A1 (es) 1974-03-15
AU461281B2 (en) 1975-05-22
IE36597L (en) 1973-02-05
GB1404368A (en) 1975-08-28
NL151261B (nl) 1976-11-15
HU165815B (es) 1974-11-28
ES405555A1 (es) 1975-07-01
IE36598B1 (en) 1976-12-08
SE406587B (sv) 1979-02-19
NO134113C (es) 1976-08-18
FR2150736B1 (es) 1976-04-16
AR197156A1 (es) 1974-03-15
DK131857B (da) 1975-09-15
AT320658B (de) 1975-02-25
AT317233B (de) 1974-08-26
JPS4826781A (es) 1973-04-09
DK143159C (da) 1981-11-16
JPS5116430B2 (es) 1976-05-24
GB1404367A (en) 1975-08-28
AR194123A1 (es) 1973-06-22
CH577980A5 (es) 1976-07-30
SU513622A3 (ru) 1976-05-05
ZA725202B (en) 1973-04-25
LU65856A1 (es) 1973-01-15
IE36598L (en) 1973-02-05
DK131857C (da) 1976-02-16
BE787139A (fr) 1972-12-01
CA966489A (en) 1975-04-22
FR2150735B1 (es) 1976-04-16
YU201372A (en) 1980-04-30
DE2238566A1 (de) 1973-02-15
SU577986A3 (ru) 1977-10-25
CS180587B2 (en) 1978-01-31
NO134113B (es) 1976-05-10
ES405456A1 (es) 1975-07-16
YU35245B (en) 1980-10-31
DE2237832A1 (de) 1973-02-15
NL7210370A (es) 1973-02-07
AU4484372A (en) 1974-01-24
CS180588B2 (en) 1978-01-31
US3864343A (en) 1975-02-04
FR2150736A1 (es) 1973-04-13
LU65855A1 (es) 1973-01-15

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