CA990291A - Process for the preparation of new biguanide derivatives - Google Patents

Process for the preparation of new biguanide derivatives

Info

Publication number
CA990291A
CA990291A CA149,783A CA149783A CA990291A CA 990291 A CA990291 A CA 990291A CA 149783 A CA149783 A CA 149783A CA 990291 A CA990291 A CA 990291A
Authority
CA
Canada
Prior art keywords
preparation
biguanide derivatives
new
new biguanide
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA149,783A
Other languages
English (en)
Other versions
CA149783S (en
Inventor
Jan Aron-Samuel M.D.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ARON MD SAMUEL J
Original Assignee
ARON MD SAMUEL J
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ARON MD SAMUEL J filed Critical ARON MD SAMUEL J
Application granted granted Critical
Publication of CA990291A publication Critical patent/CA990291A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA149,783A 1971-08-20 1972-08-15 Process for the preparation of new biguanide derivatives Expired CA990291A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3923471 1971-08-20

Publications (1)

Publication Number Publication Date
CA990291A true CA990291A (en) 1976-06-01

Family

ID=10408432

Family Applications (1)

Application Number Title Priority Date Filing Date
CA149,783A Expired CA990291A (en) 1971-08-20 1972-08-15 Process for the preparation of new biguanide derivatives

Country Status (12)

Country Link
US (1) US3808224A (xx)
JP (1) JPS4829773A (xx)
AT (1) AT317919B (xx)
AU (1) AU461429B2 (xx)
BE (1) BE787327A (xx)
CA (1) CA990291A (xx)
DE (1) DE2240887A1 (xx)
ES (1) ES405932A1 (xx)
FR (1) FR2230347B1 (xx)
GB (1) GB1351025A (xx)
NL (1) NL7211374A (xx)
ZA (1) ZA725619B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1485315A (en) * 1975-01-16 1977-09-08 Aron Soc Nouv Exploit Lab Biguanides process for their preparation and applications thereof
US4103010A (en) * 1975-01-16 1978-07-25 Aron S.A.R.L. (3-Piperazinocarbonylimino-quanidino)-isoxazoles
JPS54132566A (en) * 1978-01-18 1979-10-15 Ici Ltd Guanidine derivative*its manufacture and secretion controlling pharmaceutical composition containing it
ATE852T1 (de) * 1978-05-24 1982-04-15 Imperial Chemical Industries Plc Anti-sekretion oxadiazol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
DK185389A (da) * 1988-04-22 1989-10-23 Duphar Int Res 3,5-substituerede 1,2,4-oxadiazoler, deres fremstiling og anvendelse
DE19755016A1 (de) * 1997-12-11 1999-06-17 Bayer Ag Substituierte 2,4-Diamino-1,3,5-triazine
ZA9811445B (en) 1997-12-19 1999-08-16 Alcon Lab Inc Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions.
FR2809310B1 (fr) 2000-05-26 2004-02-13 Centre Nat Rech Scient Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant
US6936640B2 (en) * 2003-12-04 2005-08-30 Alcon, Inc. Biguanide/quaternary ammonium containing copolymeric biocides and use thereof in pharmaceutical compositions
CN102316872B (zh) * 2008-11-26 2016-12-21 萨蒂奥根制药公司 治疗肥胖症和糖尿病的胆汁酸再循环抑制剂
CN111320617A (zh) * 2018-12-17 2020-06-23 华中科技大学 苯基噁二唑类衍生物及其制备方法与应用

Also Published As

Publication number Publication date
NL7211374A (xx) 1973-02-22
US3808224A (en) 1974-04-30
AT317919B (de) 1974-09-25
GB1351025A (en) 1974-04-24
AU4572072A (en) 1974-02-21
ZA725619B (en) 1973-05-30
DE2240887A1 (de) 1973-03-01
AU461429B2 (en) 1975-05-29
BE787327A (fr) 1972-12-01
FR2230347B1 (xx) 1976-08-20
FR2230347A1 (xx) 1974-12-20
ES405932A1 (es) 1976-01-16
JPS4829773A (xx) 1973-04-19

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