CA988508A - Steroids having useful anaesthetic activity and processes for their preparation - Google Patents

Steroids having useful anaesthetic activity and processes for their preparation

Info

Publication number
CA988508A
CA988508A CA130,275A CA130275A CA988508A CA 988508 A CA988508 A CA 988508A CA 130275 A CA130275 A CA 130275A CA 988508 A CA988508 A CA 988508A
Authority
CA
Canada
Prior art keywords
steroids
processes
preparation
anaesthetic activity
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA130,275A
Other languages
English (en)
Other versions
CA130275S (en
Inventor
Christopher E. Newall
Martin C. Cook
Leslie Stephenson
Robin Lawrence
Gordon H. Phillipps
Anne C. Hunter
Niall G. Weir
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB6006470A external-priority patent/GB1380246A/en
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Application granted granted Critical
Publication of CA988508A publication Critical patent/CA988508A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
CA130,275A 1970-12-17 1971-12-16 Steroids having useful anaesthetic activity and processes for their preparation Expired CA988508A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB6006470A GB1380246A (en) 1970-12-17 1970-12-17 3alpha-hydroxy-androstanes and esters thereof

Publications (1)

Publication Number Publication Date
CA988508A true CA988508A (en) 1976-05-04

Family

ID=10484935

Family Applications (1)

Application Number Title Priority Date Filing Date
CA130,275A Expired CA988508A (en) 1970-12-17 1971-12-16 Steroids having useful anaesthetic activity and processes for their preparation

Country Status (9)

Country Link
AU (1) AU473167B2 (da)
BE (1) BE776786A (da)
CA (1) CA988508A (da)
CH (1) CH616691A5 (da)
DE (1) DE2162555A1 (da)
DK (1) DK133682B (da)
FR (1) FR2118117B1 (da)
IL (1) IL38376A (da)
ZA (1) ZA718466B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1434919A (en) * 1972-06-15 1976-05-12 Glaxo Lab Ltd 3alpha-hydroxy androstanes
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
EP0701444B1 (en) 1993-05-24 2010-04-07 Purdue Pharma Ltd. Methods and compositions for inducing sleep
CN1649614A (zh) 2002-02-22 2005-08-03 新河药品股份有限公司 活性剂传递系统和保护及施用活性剂的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH273860A (de) * 1942-04-25 1951-02-28 Nv Organon Verfahren zur Herstellung einer im Ring C eine sauerstoffhaltige Gruppe enthaltenden Verbindung der Cyclopentanopolyhydrophenanthren-Reihe.
US2824871A (en) * 1951-11-29 1958-02-25 Upjohn Co Steroid compounds and process
FR1281205A (fr) * 1956-12-21 1962-01-12 Organon Nv Procédé d'obtention de composés de la série du prégnane

Also Published As

Publication number Publication date
AU473167B2 (en) 1976-06-17
DE2162555A1 (de) 1972-06-22
FR2118117B1 (da) 1975-12-26
ZA718466B (en) 1973-08-29
BE776786A (fr) 1972-06-16
IL38376A0 (en) 1972-02-29
IL38376A (en) 1977-07-31
DK133682B (da) 1976-06-28
FR2118117A1 (da) 1972-07-28
CH616691A5 (en) 1980-04-15
AU3696271A (en) 1973-06-21
DK133682C (da) 1976-12-20

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