CA986922A - Acylamino-cephalosporanic acids and process for their manufacture - Google Patents

Acylamino-cephalosporanic acids and process for their manufacture

Info

Publication number
CA986922A
CA986922A CA139,681A CA139681A CA986922A CA 986922 A CA986922 A CA 986922A CA 139681 A CA139681 A CA 139681A CA 986922 A CA986922 A CA 986922A
Authority
CA
Canada
Prior art keywords
acylamino
manufacture
cephalosporanic acids
cephalosporanic
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA139,681A
Other languages
English (en)
Other versions
CA139681S (en
Inventor
Manfred Schorr
Elmar Schrinner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of CA986922A publication Critical patent/CA986922A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/32—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
CA139,681A 1971-04-17 1972-04-14 Acylamino-cephalosporanic acids and process for their manufacture Expired CA986922A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19712118635 DE2118635A1 (de) 1971-04-17 1971-04-17 Acylaminocephalosporansäuren und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
CA986922A true CA986922A (en) 1976-04-06

Family

ID=5804953

Family Applications (1)

Application Number Title Priority Date Filing Date
CA139,681A Expired CA986922A (en) 1971-04-17 1972-04-14 Acylamino-cephalosporanic acids and process for their manufacture

Country Status (10)

Country Link
US (1) US3865820A (de)
AT (1) AT315370B (de)
BE (1) BE782212A (de)
CA (1) CA986922A (de)
CH (1) CH567034A5 (de)
DE (1) DE2118635A1 (de)
FR (1) FR2133810B1 (de)
GB (1) GB1382494A (de)
NL (1) NL7204887A (de)
SE (1) SE390538B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7305936A (de) * 1972-05-05 1973-11-07
DE2359544A1 (de) * 1973-11-29 1975-10-30 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
GB1500010A (en) * 1975-10-01 1978-02-08 Pierrel Spa 3,7-disubstituted cephalosporins and their preparation
US4031083A (en) * 1975-10-24 1977-06-21 Yeda Research And Development Co., Ltd. Cephalosporin antibiotics
US4045438A (en) * 1975-10-24 1977-08-30 Yeda Research And Development Co. Ltd. Cephalosporin antibiotics
US4026887A (en) * 1975-10-24 1977-05-31 Yeda Research & Development Co. Ltd. Cephalosporin antibiotics
US4063019A (en) * 1976-03-30 1977-12-13 E. R. Squibb & Sons, Inc. [[[(2,4-Dioxo-1-imidazolidinyl)amino]carbonyl]amino]-acetylcephalosporin derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1445633A1 (de) * 1963-10-07 1968-12-05 Ciba Geigy Verfahren zur Herstellung neuer Amide
US3492297A (en) * 1965-07-01 1970-01-27 Merck & Co Inc Guanidino cephalosporins
US3457257A (en) * 1967-05-11 1969-07-22 Parke Davis & Co 6-aminopenicillanic acid and 7-aminocephalosporanic acid derivatives
US3575969A (en) * 1968-03-04 1971-04-20 Lilly Co Eli Desacetoxycephalosporin antibiotics
US3708477A (en) * 1968-06-27 1973-01-02 Roussel Uclaf Process of total synthesis of cephalosporin derivatives and intermediates
US3632578A (en) * 1968-09-09 1972-01-04 Lilly Co Eli Cleavage of acylamidocephalosporins and acylamidopenicillins
US3579506A (en) * 1968-10-23 1971-05-18 R & L Molecular Research Ltd Alpha-aminoisothiazolylacetic acids and their penicillin and cephalosporin derivatives
BE756747A (fr) * 1969-09-27 1971-03-29 Hoechst Ag Acides acylamino-penicillaniques doues de proprietes anti- bacterienne

Also Published As

Publication number Publication date
GB1382494A (en) 1975-02-05
BE782212A (fr) 1972-07-17
FR2133810A1 (de) 1972-12-01
NL7204887A (de) 1972-10-19
CH567034A5 (de) 1975-09-30
AT315370B (de) 1974-05-27
FR2133810B1 (de) 1975-10-31
SE390538B (sv) 1976-12-27
DE2118635A1 (de) 1972-11-02
US3865820A (en) 1975-02-11

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