CA980279A - Microbial modification of benzodiazepine compounds - Google Patents

Microbial modification of benzodiazepine compounds

Info

Publication number
CA980279A
CA980279A CA145,026A CA145026A CA980279A CA 980279 A CA980279 A CA 980279A CA 145026 A CA145026 A CA 145026A CA 980279 A CA980279 A CA 980279A
Authority
CA
Canada
Prior art keywords
benzodiazepine compounds
microbial modification
microbial
modification
benzodiazepine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA145,026A
Other languages
English (en)
Other versions
CA145026S (en
Inventor
Hiroo Wada
Fumitaka Kishimoto
Shigeho Inaba
Hisao Yamamoto
Shigeo Ogino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Application granted granted Critical
Publication of CA980279A publication Critical patent/CA980279A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y10S435/896—Streptomyces fradiae
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y10S435/897—Streptomyces griseus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA145,026A 1971-06-18 1972-06-19 Microbial modification of benzodiazepine compounds Expired CA980279A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP46044060A JPS5011999B1 (nl) 1971-06-18 1971-06-18

Publications (1)

Publication Number Publication Date
CA980279A true CA980279A (en) 1975-12-23

Family

ID=12681065

Family Applications (1)

Application Number Title Priority Date Filing Date
CA145,026A Expired CA980279A (en) 1971-06-18 1972-06-19 Microbial modification of benzodiazepine compounds

Country Status (15)

Country Link
US (1) US3806418A (nl)
JP (1) JPS5011999B1 (nl)
AU (1) AU443801B2 (nl)
BE (1) BE785008A (nl)
CA (1) CA980279A (nl)
CH (1) CH576456A5 (nl)
DE (1) DE2229486A1 (nl)
FI (1) FI52343C (nl)
FR (1) FR2142052B1 (nl)
GB (1) GB1374492A (nl)
HU (1) HU164979B (nl)
NL (1) NL154503B (nl)
PL (1) PL87018B1 (nl)
SE (1) SE395454B (nl)
ZA (1) ZA723851B (nl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES405260A1 (es) * 1972-07-28 1975-07-01 Stabilimenti Chim Farmac Riuni Procedimiento para la preparacion de 3-hidroxi-5-aril-7- sustituidos-1, 3-dihidro-2h-1, 4-benzodiacepin-2-onas.
US4208327A (en) * 1979-04-03 1980-06-17 G. D. Searle & Co. 5-Aryl-1-(2-oxazolin-2-yl)-1H-1,4-benzodiazepines and related compounds
US5559017A (en) * 1989-08-09 1996-09-24 E. R. Squibb & Sons, Inc. Microbial reduction of benzazepines and benzothiazepine derivatives
CN105601576A (zh) * 2016-03-18 2016-05-25 山东新华制药股份有限公司 氯甲西泮的晶型及其制备方法

Also Published As

Publication number Publication date
FR2142052A1 (nl) 1973-01-26
US3806418A (en) 1974-04-23
NL154503B (nl) 1977-09-15
FI52343B (nl) 1977-05-02
PL87018B1 (nl) 1976-06-30
GB1374492A (en) 1974-11-20
ZA723851B (en) 1973-03-28
AU443801B2 (en) 1974-01-03
FR2142052B1 (nl) 1977-12-23
DE2229486A1 (de) 1973-01-04
HU164979B (nl) 1974-05-28
AU4346272A (en) 1974-01-03
BE785008A (fr) 1972-10-16
CH576456A5 (nl) 1976-06-15
JPS5011999B1 (nl) 1975-05-08
FI52343C (fi) 1977-08-10
NL7208294A (nl) 1972-12-20
SE395454B (sv) 1977-08-15

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