CA958018A - Guanidines - Google Patents

Guanidines

Info

Publication number
CA958018A
CA958018A CA032,413A CA32413A CA958018A CA 958018 A CA958018 A CA 958018A CA 32413 A CA32413 A CA 32413A CA 958018 A CA958018 A CA 958018A
Authority
CA
Canada
Prior art keywords
guanidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA032,413A
Other languages
English (en)
Inventor
Thomas Baum
William F. Bruce
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Application granted granted Critical
Publication of CA958018A publication Critical patent/CA958018A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA032,413A 1967-10-13 1968-10-12 Guanidines Expired CA958018A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67502667A 1967-10-13 1967-10-13
GB8629/68A GB1223491A (en) 1967-10-13 1968-02-22 Guanidines
US75449468A 1968-08-21 1968-08-21

Publications (1)

Publication Number Publication Date
CA958018A true CA958018A (en) 1974-11-19

Family

ID=27255238

Family Applications (2)

Application Number Title Priority Date Filing Date
CA032,413A Expired CA958018A (en) 1967-10-13 1968-10-12 Guanidines
CA115885A Expired CA921829A (en) 1967-10-13 1971-06-17 Guanidines

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA115885A Expired CA921829A (en) 1967-10-13 1971-06-17 Guanidines

Country Status (13)

Country Link
BE (1) BE722136A (da)
CA (2) CA958018A (da)
CH (2) CH560188A5 (da)
DE (1) DE1802394C2 (da)
DK (1) DK128350B (da)
FI (1) FI49958C (da)
GB (2) GB1223491A (da)
IE (1) IE32417B1 (da)
IL (1) IL30782A (da)
IT (1) IT1062053B (da)
NL (1) NL166014C (da)
PH (1) PH10262A (da)
SE (1) SE381041B (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014108520A1 (en) * 2013-01-10 2014-07-17 Medical Research Council Benzylideneguanidine derivatives and therapeutic use for the treatment of protein misfolding diseases

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH523232A (de) * 1968-12-16 1972-05-31 Sandoz Ag Verfahren zur Herstellung eines Benzylidenaminoguanidins
DK153787C (da) * 1979-06-01 1989-01-16 Wellcome Found Analogifremgangsmaade til fremstilling af substituerede 3,5-diamino-6-phenyl-1,2,4-triaziner og alfa-cyanobenzyliden-aminoguanidinforbindelser til anvendelse som mellemprodukter herved
EP0021120B1 (en) * 1979-06-01 1983-04-06 The Wellcome Foundation Limited 3,5-diamino-1,2,4-triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them
DE3360148D1 (en) * 1982-02-10 1985-06-05 Beecham Group Plc Guanidine derivatives
FR2669927B1 (fr) * 1990-11-29 1994-04-08 Adir Cie Nouveaux derives de guanidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
GB2277090A (en) * 1993-04-16 1994-10-19 Shell Int Research Fungicidal tetrahydropyrimidine and imidazoline derivatives
SE9604348D0 (sv) 1996-11-26 1996-11-26 Wapharm Ab Användning av hydroxyguanidiner
WO2001025192A1 (en) * 1999-10-06 2001-04-12 Melacure Therapeutics Ab Guanidine derivatives and their use in the production of a medicament for blocking xanthine oxidase/dehydrogenase
GB0019357D0 (en) 2000-08-07 2000-09-27 Melacure Therapeutics Ab Novel phenyl guanidines
GB0108631D0 (en) * 2001-04-05 2001-05-30 Melacure Therapeutics Ab Novel benzylideneamino guanidines and their uses as ligands to the melanocortin receptors
DE10149919A1 (de) 2001-10-10 2003-04-24 Biosphings Ag Neue Salze von Guanidinderivaten und pharmazeutische Zubereitungen daraus
FR2893844B1 (fr) * 2005-11-28 2008-02-01 Centre Nat Rech Scient Utilisation du guanabenz et de ses derives pour la fabrication de medicaments pour le traitement de la mucoviscidose et de maladies liees a un defaut d'adressage des proteines dans les cellules
GB0624987D0 (en) 2006-12-14 2007-01-24 Acure Pharma Ab Novel aminoguanidines as melanocortin receptor ligands
DK3280404T3 (da) 2015-04-08 2021-11-08 Res & Innovation Uk Fremgangsmåder til valg af phosphatase-selektive og ikke-selektive phosphatasehæmmere
EP3109237A1 (en) * 2015-06-22 2016-12-28 AnaMar AB Novel 5-ht2 antagonists
US11166464B2 (en) * 2017-03-06 2021-11-09 The United States Of America, As Represented By The Secretary Of Agriculture Self-assembled active agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE958832C (de) * 1952-11-14 1957-02-28 Bayer Ag Verfahren zur Herstellung von Guanylhydrazonen
GB1019120A (en) * 1964-03-18 1966-02-02 Shell Int Research Novel hydrazine compounds and compositions containing them

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014108520A1 (en) * 2013-01-10 2014-07-17 Medical Research Council Benzylideneguanidine derivatives and therapeutic use for the treatment of protein misfolding diseases
US9682943B2 (en) 2013-01-10 2017-06-20 Medical Research Council Benzylideneguanidine derivatives and therapeutic use for the treatment of protein misfolding diseases
AU2014204831B2 (en) * 2013-01-10 2017-09-07 Inflectis Bioscience Benzylideneguanidine derivatives and therapeutic use for the treatment of protein misfolding diseases
AU2014204831C1 (en) * 2013-01-10 2018-04-05 Inflectis Bioscience Benzylideneguanidine derivatives and therapeutic use for the treatment of protein misfolding diseases
RU2654910C2 (ru) * 2013-01-10 2018-05-25 Медикал Рисёрч Каунсил Производные бензилиденгуанидина и их терапевтическое применение для лечения заболеваний, связанных с неправильным сворачиванием белков
US10100020B2 (en) 2013-01-10 2018-10-16 United Kingdom Research And Innovation Benzylideneguanidine derivatives and therapeutic use for the treatment of protein misfolding diseases
AU2017272151B2 (en) * 2013-01-10 2018-11-08 Inflectis Bioscience Benzylideneguanidine derivatives and therapeutic use for the treatment of protein misfolding diseases
US10526297B2 (en) 2013-01-10 2020-01-07 Inflectis Bioscience Benzylideneguanidine derivatives and therapeutic use for the treatment of protein misfolding diseases
US10954198B2 (en) 2013-01-10 2021-03-23 United Kingdom Research And Innovation Benzylideneguanidine derivatives and therapeutic use for the treatment of protein misfolding diseases

Also Published As

Publication number Publication date
IE32417B1 (en) 1973-07-25
DE1802394A1 (de) 1969-05-08
FI49958C (fi) 1975-11-10
FI49958B (da) 1975-07-31
NL6814608A (da) 1969-04-15
GB1223491A (en) 1971-02-24
BE722136A (da) 1969-04-10
SE381041B (sv) 1975-11-24
PH10262A (en) 1976-10-20
CH560188A5 (da) 1975-03-27
IL30782A (en) 1972-08-30
IE32417L (en) 1969-04-13
NL166014C (nl) 1981-06-15
CH524577A (de) 1972-06-30
DK128350B (da) 1974-04-16
DE1802394C2 (de) 1984-06-28
IT1062053B (it) 1983-06-25
GB1223492A (en) 1971-02-24
CA921829A (en) 1973-02-27
NL166014B (nl) 1981-01-15

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