CA946844A - Benzodiazepine derivatives and salts thereof - Google Patents

Benzodiazepine derivatives and salts thereof

Info

Publication number
CA946844A
CA946844A CA082,564A CA82564A CA946844A CA 946844 A CA946844 A CA 946844A CA 82564 A CA82564 A CA 82564A CA 946844 A CA946844 A CA 946844A
Authority
CA
Canada
Prior art keywords
salts
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA082,564A
Other languages
English (en)
Inventor
Toshiyuki Hirohashi
Michihiro Yamamoto
Takahiro Izumi
Shigeho Inaba
Yoshiharu Kume
Hisao Yamamoto
Kazuo Mori
Kikuo Ishizumi
Isamu Maruyama
Mitsuhiro Akatsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Application granted granted Critical
Publication of CA946844A publication Critical patent/CA946844A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C07D243/36—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing an indole or hydrogenated indole ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA082,564A 1969-05-16 1970-05-12 Benzodiazepine derivatives and salts thereof Expired CA946844A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP44038183A JPS4811718B1 (fr) 1969-05-16 1969-05-16

Publications (1)

Publication Number Publication Date
CA946844A true CA946844A (en) 1974-05-07

Family

ID=12518255

Family Applications (1)

Application Number Title Priority Date Filing Date
CA082,564A Expired CA946844A (en) 1969-05-16 1970-05-12 Benzodiazepine derivatives and salts thereof

Country Status (12)

Country Link
JP (1) JPS4811718B1 (fr)
AT (2) AT300815B (fr)
BE (1) BE750524A (fr)
CA (1) CA946844A (fr)
CH (1) CH537396A (fr)
CS (1) CS169804B2 (fr)
ES (2) ES379701A1 (fr)
FR (1) FR2051534B1 (fr)
GB (1) GB1272887A (fr)
NL (1) NL161749C (fr)
SE (1) SE372269B (fr)
ZA (1) ZA703130B (fr)

Also Published As

Publication number Publication date
AT300815B (de) 1972-08-10
NL161749C (nl) 1980-03-17
AT308125B (de) 1973-06-25
ZA703130B (en) 1971-01-27
BE750524A (fr) 1970-10-16
NL7007057A (fr) 1970-11-18
CS169804B2 (fr) 1976-07-29
ES379701A1 (es) 1972-08-01
ES383587A1 (es) 1973-01-01
SE372269B (fr) 1974-12-16
GB1272887A (en) 1972-05-03
DE2023182B2 (de) 1975-08-28
FR2051534B1 (fr) 1974-04-12
FR2051534A1 (fr) 1971-04-09
JPS4811718B1 (fr) 1973-04-14
NL161749B (nl) 1979-10-15
CH537396A (de) 1973-05-31
DE2023182A1 (de) 1970-11-19

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