CA945139A - PROCESS FOR THE PREPARATION OF 21-CHLORO-6,6 9.alpha.-TRIFLUORO-11.beta.,16.alpha.,17.alpha.-TRIHYDROXY-1,4-PREGNADIEN-3,20-DIONE 16,17-KETALS AND SELECTED INTERMEDIATES - Google Patents
PROCESS FOR THE PREPARATION OF 21-CHLORO-6,6 9.alpha.-TRIFLUORO-11.beta.,16.alpha.,17.alpha.-TRIHYDROXY-1,4-PREGNADIEN-3,20-DIONE 16,17-KETALS AND SELECTED INTERMEDIATESInfo
- Publication number
- CA945139A CA945139A CA123,803A CA123803A CA945139A CA 945139 A CA945139 A CA 945139A CA 123803 A CA123803 A CA 123803A CA 945139 A CA945139 A CA 945139A
- Authority
- CA
- Canada
- Prior art keywords
- alpha
- pregnadien
- ketals
- trihydroxy
- dione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/913—Aspergillus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/939—Rhizopus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA171,446A CA943953A (en) | 1971-02-01 | 1973-05-15 | PROCESS FOR THE PREPARATION OF 21-CHLORO-6,6,9.alpha.-TRIFLUORO-11.beta.,16.alpha.,17.alpha.-TRIHYDROXY-1,4-PREGNADIEN-3,20-DIONE 16,17-KETALS AND SELECTED INTERMEDIATES |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11161571A | 1971-02-01 | 1971-02-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA945139A true CA945139A (en) | 1974-04-09 |
Family
ID=22339486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA123,803A Expired CA945139A (en) | 1971-02-01 | 1971-09-27 | PROCESS FOR THE PREPARATION OF 21-CHLORO-6,6 9.alpha.-TRIFLUORO-11.beta.,16.alpha.,17.alpha.-TRIHYDROXY-1,4-PREGNADIEN-3,20-DIONE 16,17-KETALS AND SELECTED INTERMEDIATES |
Country Status (14)
Country | Link |
---|---|
US (1) | US3718673A (es) |
AT (1) | AT308294B (es) |
AU (1) | AU3452371A (es) |
BE (1) | BE774754A (es) |
CA (1) | CA945139A (es) |
DE (1) | DE2149798A1 (es) |
DK (1) | DK129514B (es) |
ES (1) | ES396031A1 (es) |
FR (1) | FR2124218B1 (es) |
GB (3) | GB1363458A (es) |
IL (1) | IL37798A0 (es) |
NL (1) | NL7113713A (es) |
SU (1) | SU438181A3 (es) |
ZA (1) | ZA716382B (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4272446A (en) * | 1974-02-27 | 1981-06-09 | Pierrel S.P.A. | Steroids and process for preparing the same |
NL7502252A (nl) * | 1974-02-27 | 1975-08-29 | Pierrel Spa | Werkwijze voor het bereiden van een geneesmid- del met anti-inflammatoire werking, gevormd ge- neesmiddel verkregen volgens deze werkwijze alsmede werkwijze voor het bereiden van in het geneesmiddel gebruikte nieuwe steroiden. |
DE2655570A1 (de) * | 1975-12-12 | 1977-06-16 | Ciba Geigy Ag | Neue polyhalogensteroide und verfahren zu ihrer herstellung |
EP0055832B1 (de) * | 1980-12-23 | 1986-02-26 | Schering Aktiengesellschaft | Verfahren zur Herstellung von 11-beta,21-Dihydroxy-2'-methyl-5'-beta-H-1,4-pregnadien-(16,17)-oxazol-3,20-dion |
CN102061320B (zh) * | 2010-12-02 | 2013-04-03 | 浙江仙琚制药股份有限公司 | 11α,17α-二羟基-雄甾-4-烯-3,20-二酮的制备方法 |
US9109005B2 (en) | 2012-02-23 | 2015-08-18 | Boehringer Ingelheim International Gmbh | Method for manufacturing of ciclesonide |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3338928A (en) * | 1965-09-09 | 1967-08-29 | Syntex Corp | Fused halocyclopropyl steroids |
US3546215A (en) * | 1967-10-18 | 1970-12-08 | Syntex Corp | 6-gem-difluoro steroids |
-
1971
- 1971-02-01 US US00111615A patent/US3718673A/en not_active Expired - Lifetime
- 1971-09-22 DK DK463071AA patent/DK129514B/da unknown
- 1971-09-23 ZA ZA716382A patent/ZA716382B/xx unknown
- 1971-09-24 GB GB4472871A patent/GB1363458A/en not_active Expired
- 1971-09-24 GB GB437374A patent/GB1363460A/en not_active Expired
- 1971-09-27 IL IL37798A patent/IL37798A0/xx unknown
- 1971-09-27 CA CA123,803A patent/CA945139A/en not_active Expired
- 1971-10-06 DE DE19712149798 patent/DE2149798A1/de active Pending
- 1971-10-06 NL NL7113713A patent/NL7113713A/xx unknown
- 1971-10-13 AU AU34523/71A patent/AU3452371A/en not_active Expired
- 1971-10-14 AT AT888171A patent/AT308294B/de not_active IP Right Cessation
- 1971-10-15 ES ES396031A patent/ES396031A1/es not_active Expired
- 1971-10-28 FR FR7138737A patent/FR2124218B1/fr not_active Expired
- 1971-10-29 BE BE774754A patent/BE774754A/xx unknown
-
1972
- 1972-01-27 SU SU1742287A patent/SU438181A3/ru active
-
1974
- 1974-01-30 GB GB437271*[A patent/GB1363459A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE2149798A1 (de) | 1972-08-03 |
US3718673A (en) | 1973-02-27 |
BE774754A (fr) | 1972-05-02 |
GB1363458A (en) | 1974-08-14 |
ZA716382B (en) | 1972-07-26 |
GB1363459A (en) | 1974-08-14 |
DK129514B (da) | 1974-10-21 |
NL7113713A (es) | 1972-08-03 |
ES396031A1 (es) | 1975-02-16 |
SU438181A3 (ru) | 1974-07-30 |
AT308294B (de) | 1973-06-25 |
AU3452371A (en) | 1973-04-19 |
FR2124218B1 (es) | 1975-03-14 |
DK129514C (es) | 1975-03-17 |
FR2124218A1 (es) | 1972-09-22 |
IL37798A0 (en) | 1971-11-29 |
GB1363460A (en) | 1974-08-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA945139A (en) | PROCESS FOR THE PREPARATION OF 21-CHLORO-6,6 9.alpha.-TRIFLUORO-11.beta.,16.alpha.,17.alpha.-TRIHYDROXY-1,4-PREGNADIEN-3,20-DIONE 16,17-KETALS AND SELECTED INTERMEDIATES | |
CA972744A (en) | PROCESS FOR THE PREPARATION OF 3.alpha.-HYDROXYSTEROIDS | |
CA895860A (en) | PROCESS FOR THE PREPARATION OF 3.alpha.-HYDROXY-5.beta.-PREGNAN-20-ONE | |
CA943953A (en) | PROCESS FOR THE PREPARATION OF 21-CHLORO-6,6,9.alpha.-TRIFLUORO-11.beta.,16.alpha.,17.alpha.-TRIHYDROXY-1,4-PREGNADIEN-3,20-DIONE 16,17-KETALS AND SELECTED INTERMEDIATES | |
CA969175A (en) | 6.alpha.,9.alpha.-DIFLUOROSTEROIDS OF THE PREGNANE SERIES AND PROCESSES FOR THEIR MANUFACTURE | |
CA943950A (en) | PROCESS FOR THE PREPARATION OF 17.beta.-HYDROXY-17.alpha.-PROPADIENYL STEROIDS | |
CA977334A (en) | 14,15.beta.-EPOXYCARDENOLIDE- AND 14,15.beta.-EPOXYBUFADIENOLIDE-GLYCOSIDES AND PROCESS FOR THEIR PREPARATION | |
CA866786A (en) | PROCESS FOR THE PREPARATION OF 16.alpha.-METHYL-9.alpha.-FLUORO-11.beta.,17.alpha.,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE-21-ACYLATES | |
CA976155A (en) | PROCESS FOR PREPARING 17-ESTERS OF 6.alpha.,9.alpha.-DIFLUORO-21-DESOXYPREDNISOLONE | |
CA1015744A (en) | 15.alpha. - SULFONYLOXY - 12.beta. - HYDROXYPREGNANES AND PROCESS FOR THE PREPARATION THEREOF | |
CA887641A (en) | 11.beta., 17.alpha.-DIHYDROXY-16-METHYLENEPROGESTERONES AND PROCESSES OF PREPARATION | |
CA888163A (en) | INVERTED STEPS FOR THE PREPARATION OF 9.alpha.-FLUORO-16-METHYLENE-PREDNISOLONE OR -PREDNISONE AND 21-ESTERS THEREOF | |
CA947768A (en) | PROCESS FOR THE PREPARATION OF DEA-9.beta.-STEROIDS | |
CA865098A (en) | PROCESS FOR THE PRODUCTION OF 17.alpha.-HALOETHYNYL-17.beta.-HYDROXYESTR-5(10)-EN-3-ONE AND 17-ESTERS THEREOF | |
CA912548A (en) | NOVEL PROCESSES FOR THE PREPARATION OF 7.beta., 17.alpha.-DIMETHYL-17-HYDROXYANDROST-4-EN-3-ONE AND ITS ACYLATES | |
CA870023A (en) | PROCESS FOR THE PREPARATION OF .beta.-HALOGENO-ALKYL-ISOCYANATES | |
CA930729A (en) | 11.beta.-METHYL-17.alpha.-ALKADIENYL-SUBSTITUTED STEROIDS | |
CA890412A (en) | PROCESS FOR THE PREPARATION OF 17.alpha.-HALOGENOALKYNYL-13-LOWER ALKYLGON-4 OR 5(10)-EN-3-ON-17.beta.-OLS OR 3,17.beta.-DIOLS AND THEIR ESTERS AND ETHERS | |
CA932718A (en) | PROCESS FOR THE PREPARATION OF 9.beta., 11.beta.-EPOXY STEROIDS | |
CA866780A (en) | 9.beta.,10.alpha. STEROIDS | |
CA861501A (en) | 6-METHYL-9.beta., 11.beta.-OXIDO-16.alpha.,17.alpha.-21-TRIHYDROXY STEROIDS | |
CA860926A (en) | 6.beta.7.beta.-DIHALO-METHYLENE STEROIDS AND PROCESS FOR MAKING SAME | |
CA864547A (en) | PREPARATION OF .DELTA.1,4-PREGNADIENE-17.alpha.,21-DIOL-3,11,20-TRIONE | |
CA881509A (en) | 17.alpha.-ACYLOXY-11.beta.-METHYL-19-NORPREGN-4-ENE-3,20-DIONES AND DERIVATIVES THEREOF | |
CA877302A (en) | 6.beta.,7.beta.-METHYLENE AND 6.beta.,7.beta.-MONOHALOMETHYLENE STEROIDS AND PROCESSES FOR MAKING SAME |