AT308294B - Verfahren zur Herstellung des neuen 6,6-Difluor-11α, 16α, 17α-trihydroxy-4-pregnen-3,20-dions - Google Patents

Verfahren zur Herstellung des neuen 6,6-Difluor-11α, 16α, 17α-trihydroxy-4-pregnen-3,20-dions

Info

Publication number
AT308294B
AT308294B AT888171A AT888171A AT308294B AT 308294 B AT308294 B AT 308294B AT 888171 A AT888171 A AT 888171A AT 888171 A AT888171 A AT 888171A AT 308294 B AT308294 B AT 308294B
Authority
AT
Austria
Prior art keywords
pregnen
trihydroxy
dione
difluoro
preparation
Prior art date
Application number
AT888171A
Other languages
English (en)
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Application granted granted Critical
Publication of AT308294B publication Critical patent/AT308294B/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/913—Aspergillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/939—Rhizopus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT888171A 1971-02-01 1971-10-14 Verfahren zur Herstellung des neuen 6,6-Difluor-11α, 16α, 17α-trihydroxy-4-pregnen-3,20-dions AT308294B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11161571A 1971-02-01 1971-02-01

Publications (1)

Publication Number Publication Date
AT308294B true AT308294B (de) 1973-06-25

Family

ID=22339486

Family Applications (1)

Application Number Title Priority Date Filing Date
AT888171A AT308294B (de) 1971-02-01 1971-10-14 Verfahren zur Herstellung des neuen 6,6-Difluor-11α, 16α, 17α-trihydroxy-4-pregnen-3,20-dions

Country Status (14)

Country Link
US (1) US3718673A (de)
AT (1) AT308294B (de)
AU (1) AU3452371A (de)
BE (1) BE774754A (de)
CA (1) CA945139A (de)
DE (1) DE2149798A1 (de)
DK (1) DK129514B (de)
ES (1) ES396031A1 (de)
FR (1) FR2124218B1 (de)
GB (3) GB1363458A (de)
IL (1) IL37798A0 (de)
NL (1) NL7113713A (de)
SU (1) SU438181A3 (de)
ZA (1) ZA716382B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4272446A (en) * 1974-02-27 1981-06-09 Pierrel S.P.A. Steroids and process for preparing the same
NL7502252A (nl) * 1974-02-27 1975-08-29 Pierrel Spa Werkwijze voor het bereiden van een geneesmid- del met anti-inflammatoire werking, gevormd ge- neesmiddel verkregen volgens deze werkwijze alsmede werkwijze voor het bereiden van in het geneesmiddel gebruikte nieuwe steroiden.
DE2655570A1 (de) * 1975-12-12 1977-06-16 Ciba Geigy Ag Neue polyhalogensteroide und verfahren zu ihrer herstellung
DE3173923D1 (en) * 1980-12-23 1986-04-03 Schering Ag Process for the preparation of 11-beta, 21-dihydroxy-2'-methyl-5'-beta-h-1,4-pregnadieno-(16,17-d)-oxazole-3,20-dione
CN102061320B (zh) * 2010-12-02 2013-04-03 浙江仙琚制药股份有限公司 11α，17α-二羟基-雄甾-4-烯-3，20-二酮的制备方法
US9109005B2 (en) * 2012-02-23 2015-08-18 Boehringer Ingelheim International Gmbh Method for manufacturing of ciclesonide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3338928A (en) * 1965-09-09 1967-08-29 Syntex Corp Fused halocyclopropyl steroids
US3546215A (en) * 1967-10-18 1970-12-08 Syntex Corp 6-gem-difluoro steroids

Also Published As

Publication number Publication date
DK129514B (da) 1974-10-21
FR2124218B1 (de) 1975-03-14
DK129514C (de) 1975-03-17
CA945139A (en) 1974-04-09
ES396031A1 (es) 1975-02-16
GB1363458A (en) 1974-08-14
IL37798A0 (en) 1971-11-29
SU438181A3 (ru) 1974-07-30
GB1363460A (en) 1974-08-14
FR2124218A1 (de) 1972-09-22
US3718673A (en) 1973-02-27
BE774754A (fr) 1972-05-02
DE2149798A1 (de) 1972-08-03
NL7113713A (de) 1972-08-03
GB1363459A (en) 1974-08-14
AU3452371A (en) 1973-04-19
ZA716382B (en) 1972-07-26

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee