CA924306A - Compounds of the dihydro-lysergic and -isolysergic acid series and process for preparing same - Google Patents

Compounds of the dihydro-lysergic and -isolysergic acid series and process for preparing same

Info

Publication number
CA924306A
CA924306A CA113255A CA113255A CA924306A CA 924306 A CA924306 A CA 924306A CA 113255 A CA113255 A CA 113255A CA 113255 A CA113255 A CA 113255A CA 924306 A CA924306 A CA 924306A
Authority
CA
Canada
Prior art keywords
lysergic
dihydro
compounds
acid series
preparing same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA113255A
Other languages
English (en)
Other versions
CA113255S (en
Inventor
Wolf Lajos
Borsi Jozsef
Mago Erzsebet
Balogh Tibor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Application granted granted Critical
Publication of CA924306A publication Critical patent/CA924306A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C07D457/08—Lysergic acid amides in which the amide nitrogen is a member of a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA113255A 1970-05-18 1971-05-18 Compounds of the dihydro-lysergic and -isolysergic acid series and process for preparing same Expired CA924306A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUGO001135 1970-05-18

Publications (1)

Publication Number Publication Date
CA924306A true CA924306A (en) 1973-04-10

Family

ID=10996683

Family Applications (1)

Application Number Title Priority Date Filing Date
CA113255A Expired CA924306A (en) 1970-05-18 1971-05-18 Compounds of the dihydro-lysergic and -isolysergic acid series and process for preparing same

Country Status (12)

Country Link
JP (1) JPS5634598B1 (en:Method)
AT (1) AT347047B (en:Method)
CA (1) CA924306A (en:Method)
CH (2) CH590277A5 (en:Method)
CS (1) CS179371B2 (en:Method)
DE (1) DE2124640C2 (en:Method)
DK (1) DK142874B (en:Method)
GB (1) GB1345546A (en:Method)
NL (1) NL172825C (en:Method)
SE (2) SE396753B (en:Method)
SU (1) SU400091A3 (en:Method)
YU (1) YU35770B (en:Method)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4064249A (en) * 1974-05-28 1977-12-20 Richter Gedeon Vegyeszeti Gyar Rt. Compounds with ergoline skeleton
HU169073B (en:Method) * 1974-05-28 1976-09-28
HU172649B (hu) * 1975-04-24 1978-11-28 Gyogyszerkutato Intezet Sposob poluchenija novykh biologicheski aktivnykh lizergamidov
DE3001752A1 (de) * 1980-01-16 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen
NL189462C (nl) * 1980-04-03 1993-04-16 Erba Carlo Spa Ergolinederivaten met antiprolactinische en/of antihypertensieve eigenschappen en farmaceutische preparaat daarvan.
US4902691A (en) * 1988-12-19 1990-02-20 Eli Lilly And Company Heteroalkylamides of (8-β)-1-alkyl-6-(substituted)ergolines useful for blocking 5HT2 receptors
US4914107A (en) * 1989-01-17 1990-04-03 Eli Lilly And Company Method for selectively blocking 5-HT2 receptors
US5441961A (en) * 1992-08-27 1995-08-15 Eli Lilly And Company Substituted cyclo or bicycloalkylamides of (8β)-6-(substituted) ergolines
BR112017015487A2 (pt) 2015-01-20 2018-01-30 Xoc Pharmaceuticals Inc Composto; composição; método de tratamento e/ou prevenção de enxaqueca, als, doença de alzheimer, doença de parkinson, distúrbios extrapirimidais, depressão, náusea, êmese, síndrome das pernas inquietas, insônia, agressão, doença de huntington, doença cardiopulmonar, fibrogênese, hipertensão arterial pulmonar, ansiedade, dependências a drogas, distonia, parassonia ou hiperlactinemia em um indivíduo; métodos de agonização dos receptores d2, 5-ht1d, 5-ht1a e 5-ht2c, em um indivíduo; método de antagonização do receptor d3 em um indivíduo; métodos de agonização seletiva dos receptores 5 -ht1d, e 5-ht2c, método de fornecimento de atividade de antagonista funcional no receptor 5 -ht2b ou no receptor 5-ht7, ou em ambos, em um indivíduo; método de fornecimento de atividade de antagonista funcional nos receptores adrenérgicos em um indivíduo
JP2018502889A (ja) 2015-01-20 2018-02-01 エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ イソエルゴリン化合物およびその使用
MX2019014272A (es) 2017-06-01 2020-12-11 Xoc Pharmaceuticals Inc Compuestos policiclicos y usos de los mismos.
JP7461342B2 (ja) 2018-09-12 2024-04-03 イーテーエルエーセー・ベー・フェー クレーンのシステムおよび交換可能工具

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT192546B (de) * 1956-02-27 1957-10-25 Anton Von Waldheim Chemisch Ph Verfahren zur Herstellung von Dihydrolysergsäure und deren Derivaten

Also Published As

Publication number Publication date
DK142874B (da) 1981-02-16
ATA428771A (de) 1978-04-15
DE2124640C2 (de) 1983-02-03
AT347047B (de) 1978-12-11
GB1345546A (en) 1974-01-30
CH590277A5 (en:Method) 1977-07-29
NL172825C (nl) 1983-11-01
CH567506A5 (en:Method) 1975-10-15
SE396753B (sv) 1977-10-03
DE2124640A1 (de) 1972-11-02
NL7106834A (en:Method) 1971-11-22
SU400091A3 (en:Method) 1973-10-03
NL172825B (nl) 1983-06-01
JPS5634598B1 (en:Method) 1981-08-11
DK142874C (en:Method) 1981-09-28
YU122971A (en) 1980-10-31
CS179371B2 (en) 1977-10-31
SE416302B (sv) 1980-12-15
YU35770B (en) 1981-06-30

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