CA918665A - 1,4-dihydro-1-substituted-6,7-methylene-dioxy-4-oxo-3-quinoline carboxylic acid derivatives - Google Patents

1,4-dihydro-1-substituted-6,7-methylene-dioxy-4-oxo-3-quinoline carboxylic acid derivatives

Info

Publication number
CA918665A
CA918665A CA020366A CA20366A CA918665A CA 918665 A CA918665 A CA 918665A CA 020366 A CA020366 A CA 020366A CA 20366 A CA20366 A CA 20366A CA 918665 A CA918665 A CA 918665A
Authority
CA
Canada
Prior art keywords
dioxy
dihydro
oxo
methylene
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA020366A
Inventor
Kaminsky Daniel
I. Meltzer Robert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Pharmaceutical Co filed Critical Warner Lambert Pharmaceutical Co
Application granted granted Critical
Publication of CA918665A publication Critical patent/CA918665A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA020366A 1967-05-18 1968-05-17 1,4-dihydro-1-substituted-6,7-methylene-dioxy-4-oxo-3-quinoline carboxylic acid derivatives Expired CA918665A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63930467A 1967-05-18 1967-05-18

Publications (1)

Publication Number Publication Date
CA918665A true CA918665A (en) 1973-01-09

Family

ID=24563571

Family Applications (1)

Application Number Title Priority Date Filing Date
CA020366A Expired CA918665A (en) 1967-05-18 1968-05-17 1,4-dihydro-1-substituted-6,7-methylene-dioxy-4-oxo-3-quinoline carboxylic acid derivatives

Country Status (6)

Country Link
US (1) US3524858A (en)
CA (1) CA918665A (en)
DE (1) DE1770447A1 (en)
FR (1) FR8415M (en)
GB (1) GB1220623A (en)
SE (1) SE342450B (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1194219B (en) * 1962-01-12 1965-06-03 Schaefer & Kind Armaturenfabri Quick-acting shut-off valve with a non-rising twist grip
US3966743A (en) * 1968-07-23 1976-06-29 Boehringer Mannheim G.M.B.H. Ortho fused cycloalkano-4-quinolone-3-carboxylic acid derivatives
US3907808A (en) * 1971-05-17 1975-09-23 Sterling Drug Inc 1,4-Dihydro-4-oxo-7-pyridyl-3-quinolinecarboxylic acid derivatives
US3755332A (en) * 1971-07-01 1973-08-28 Ciba Geigy Corp Substituted 4 indazolaminoquinolines
BE793524A (en) * 1971-12-30 1973-06-29 Riker Laboratories Inc BENZOQUINOLIZINE-CARBOXYLIC ACIDS AND THEIR DERIVATIVES
US4014877A (en) * 1972-11-02 1977-03-29 Riker Laboratories, Inc. Substituted benzo[ij]quinolizine-2-carboxylic acids and derivatives thereof
US3985882A (en) * 1972-11-02 1976-10-12 Riker Laboratories, Inc. Substituted benzo[ij]quinolinzine-2-carboxylic acids and derivatives thereof as bactericidal agents
US3905982A (en) * 1973-07-23 1975-09-16 Searle & Co 1-Aryl-n-dialkylaminoalkyl-3,4-dihydro-2(1H)-isoquinolinecarboxamides and related compounds
US4001244A (en) * 1973-07-23 1977-01-04 G. D. Searle & Co. 1-aryl-3,4-dihydro-2(1h)-isoquinoline carbonyl chlorides
FR2281761A1 (en) * 1974-08-13 1976-03-12 Roussel Uclaf NEW DERIVATIVES OF 3-QUINOLEINE CARBOXYLIC ACID, THEIR METHOD OF PREPARATION AND THEIR APPLICATION AS A MEDICINAL PRODUCT
US4192876A (en) * 1975-07-23 1980-03-11 Sandoz, Inc. 4-Hydroxy-3-nitro-quinoline-2(1H)-ones
JPS5324028A (en) * 1976-08-19 1978-03-06 Sumitomo Chem Co Ltd Systemic bactericide for plant
US4273930A (en) * 1977-06-20 1981-06-16 Sandoz, Inc. 4-Hydroxy-2-quinolinone-3-carboxylic acid esters
US4281131A (en) * 1977-06-20 1981-07-28 Sandoz, Inc. 4-Hydroxy-2-quinolinone-3-carboxylic acids and salts thereof
US4284777A (en) * 1978-12-26 1981-08-18 E. I. Du Pont De Nemours And Company Antibacterials: 1-difluoromethyl-6,7-methylenedioxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid and its esters
US4216324A (en) * 1978-12-26 1980-08-05 E. I. Du Pont De Nemours And Company 1-Difluoromethyl-6,7-methylenedioxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
IE52670B1 (en) * 1981-03-03 1988-01-20 Leo Ab Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation
FR2564832B1 (en) * 1984-05-23 1987-05-15 Panmedica Sa NOVEL N-ACYL DERIVATIVES OF AMINO ACIDS AND THEIR ESTERS, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM
ATE258437T1 (en) * 1995-08-02 2004-02-15 Darwin Discovery Ltd QUINOLONES AND THEIR THERAPEUTIC USE
EP0841929B1 (en) * 1995-08-02 2003-05-07 Darwin Discovery Limited Quinolones and their therapeutic use
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
ES2656017T3 (en) 2004-06-24 2018-02-22 Vertex Pharmaceuticals Incorporated Conveyor modulators of the ATP binding cassette
US8354427B2 (en) * 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
RU2528046C2 (en) * 2004-06-24 2014-09-10 Вертекс Фармасьютикалз Инкорпорейтед Modulators of atp-binding cartridge transporters
EP2502912A3 (en) * 2004-06-24 2013-11-06 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
WO2007075901A2 (en) * 2005-12-24 2007-07-05 Vertex Pharmaceuticals Incorporated Quinolin- 4 - one derivatives as modulators of abc transporters
DK3219705T3 (en) 2005-12-28 2020-04-14 Vertex Pharma PHARMACEUTICAL COMPOSITIONS OF THE AMORPHIC FORM OF N- [2,4-BIS (1,1-DIMETHYLETHYL) -5-HYDROXYPHENYL] -1,4-DIHYDRO-4-OXOQUINOLIN-3-CARBOXAMIDE
EP3330255B1 (en) 2009-03-20 2020-12-09 Vertex Pharmaceuticals Incorporated Process for making modulators of cystic fibrosis transmembrane conductance regulator
US8802700B2 (en) 2010-12-10 2014-08-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
AU2013226076B2 (en) 2012-02-27 2017-11-16 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administration thereof
JP6746569B2 (en) 2014-10-07 2020-08-26 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3172811A (en) * 1965-03-09 Quinolone proteus infection treatment
US2614121A (en) * 1946-03-01 1952-10-14 Charles C Price Process for making intermediates for producing basic compounds
FR1505313A (en) * 1962-04-09 1967-12-15 Norwich Pharma Co Lower alkyl esters of 6, 7-dialkoxy (lower) -4-hydroxy-3-quinoline carboxylic acids and process for their preparation
GB1076828A (en) * 1963-12-12 1967-07-26 Warner Lambert Pharmaceutical Methylenedioxy quinoline derivatives
US3397208A (en) * 1965-02-24 1968-08-13 Norwich Pharma Co Method for preparing 4-hydroxy-6, 7-dialkoxy-3-carboalkoxyquinolines and novel 4-chloro-6, 7-dialkoxy-3-carboalkoxyquinolines useful therein

Also Published As

Publication number Publication date
FR8415M (en) 1971-06-10
GB1220623A (en) 1971-01-27
SE342450B (en) 1972-02-07
US3524858A (en) 1970-08-18
DE1770447A1 (en) 1972-03-16

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