CA3263975A1 - INTRANASAL ADMINISTRATION OF NGF FOR THE TREATMENT OF NEUROSENSORY HEARING LOSS - Google Patents
INTRANASAL ADMINISTRATION OF NGF FOR THE TREATMENT OF NEUROSENSORY HEARING LOSSInfo
- Publication number
- CA3263975A1 CA3263975A1 CA3263975A CA3263975A CA3263975A1 CA 3263975 A1 CA3263975 A1 CA 3263975A1 CA 3263975 A CA3263975 A CA 3263975A CA 3263975 A CA3263975 A CA 3263975A CA 3263975 A1 CA3263975 A1 CA 3263975A1
- Authority
- CA
- Canada
- Prior art keywords
- ngf
- treatment
- hearing loss
- intranasal administration
- sensorineural hearing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Psychology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP22188990.0A EP4316505A1 (en) | 2022-08-05 | 2022-08-05 | Intranasal administration of ngf for the treatment of sensorineural hearing loss |
| EP22188990.0 | 2022-08-05 | ||
| PCT/EP2023/071698 WO2024028487A1 (en) | 2022-08-05 | 2023-08-04 | Intranasal administration of ngf for the treatment of sensorineural hearing loss |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3263975A1 true CA3263975A1 (en) | 2024-02-08 |
Family
ID=82846594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3263975A Pending CA3263975A1 (en) | 2022-08-05 | 2023-08-04 | INTRANASAL ADMINISTRATION OF NGF FOR THE TREATMENT OF NEUROSENSORY HEARING LOSS |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP4316505A1 (enExample) |
| JP (1) | JP2025525989A (enExample) |
| CN (1) | CN119836297A (enExample) |
| AU (1) | AU2023317864A1 (enExample) |
| CA (1) | CA3263975A1 (enExample) |
| IL (1) | IL318657A (enExample) |
| WO (1) | WO2024028487A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4623927A1 (en) | 2024-03-27 | 2025-10-01 | Dompe' Farmaceutici SpA | Ngf for use in the prevention or treatment of motor impairment caused by neonatal hypoxic-ischemic encephalopathy |
| EP4659759A1 (en) * | 2024-06-04 | 2025-12-10 | Dompé farmaceutici SpA | Administration of ngf for the treatment of niemann-pick type c disease |
| WO2026022244A1 (en) | 2024-07-23 | 2026-01-29 | Chiesi Farmaceutici S.P.A. | A polypeptide for use in the therapeutic management of acute ischaemic stroke |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE257514T1 (de) | 1998-10-09 | 2004-01-15 | Scil Proteins Gmbh | Verfahren zur gewinnung von aktivem beta-ngf |
| ITRM20110390A1 (it) * | 2011-07-21 | 2013-01-22 | Eramo Alessandra D | Prodotto per stimolare la produzione endogena di mediatori dell'infiammazione. |
| ES2545701T3 (es) | 2011-12-19 | 2015-09-15 | Wacker Chemie Ag | Nuevos mutantes de proNGF y usos de los mismos en la producción de beta-NGF |
| US20190022101A1 (en) * | 2016-01-06 | 2019-01-24 | Massachusetts Eye And Ear Infirmary | Treating Cochlear Synaptopathy |
| WO2018140792A2 (en) * | 2017-01-27 | 2018-08-02 | Otonomy, Inc. | Neurotrophin mutants for treating hearing loss and other otic disorders |
| EP3406259A1 (en) * | 2017-05-24 | 2018-11-28 | Dompé farmaceutici S.p.A. | Neurotrophins for use in the treatment of hearing loss |
| WO2019207106A1 (en) | 2018-04-27 | 2019-10-31 | Chiesi Farmaceutici Spa | Production of nerve growth factor (ngf) and of muteins thereof |
| WO2022105847A1 (en) * | 2020-11-19 | 2022-05-27 | Staidson (Beijing) Biopharmaceuticals Co. , Ltd. | Long-acting nerve growth factor polypeptides and uses thereof |
-
2022
- 2022-08-05 EP EP22188990.0A patent/EP4316505A1/en not_active Withdrawn
-
2023
- 2023-08-04 CN CN202380063408.0A patent/CN119836297A/zh active Pending
- 2023-08-04 CA CA3263975A patent/CA3263975A1/en active Pending
- 2023-08-04 IL IL318657A patent/IL318657A/en unknown
- 2023-08-04 AU AU2023317864A patent/AU2023317864A1/en active Pending
- 2023-08-04 EP EP23757837.2A patent/EP4565255A1/en active Pending
- 2023-08-04 JP JP2025507000A patent/JP2025525989A/ja active Pending
- 2023-08-04 WO PCT/EP2023/071698 patent/WO2024028487A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP4565255A1 (en) | 2025-06-11 |
| EP4316505A1 (en) | 2024-02-07 |
| CN119836297A (zh) | 2025-04-15 |
| JP2025525989A (ja) | 2025-08-07 |
| WO2024028487A1 (en) | 2024-02-08 |
| AU2023317864A1 (en) | 2025-02-13 |
| IL318657A (en) | 2025-03-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL318657A (en) | Intranasal administration of NGF for the treatment of sensorineural hearing loss | |
| CA3263977A1 (en) | INTRANASAL ADMINISTRATION OF BDNF FOR THE TREATMENT OF NEUROSENSORIAL HEARING LOSS | |
| HK40122674A (en) | Intranasal administration of ngf for the treatment of sensorineural hearing loss | |
| HK40117061A (en) | Azasetron for the treatment of sudden sensorineural hearing loss | |
| CN309556052S (en) | Hearing aid for the deaf | |
| IL315627A (en) | Azasterone for the treatment of sudden sensorineural hearing loss | |
| CN309175495S (en) | Loudspeaker part | |
| EM150383230002S (sv) | Mikrofoner (del av -) | |
| EM150383230004S (sv) | Mikrofoner (del av -) | |
| EM150383230005S (sk) | Mikrofóny (časť - ) | |
| EM150383230003S (sv) | Mikrofoner (del av -) | |
| EM150383230007S (sv) | Mikrofoner (del av -) | |
| EM150383230001S (sv) | Mikrofoner (del av -) | |
| EM150383230006S (sv) | Mikrofoner (del av -) | |
| EM150225380003S (bg) | Говорители (Част от -) | |
| EM150225380002S (bg) | Говорители (Част от -) | |
| CA3295036A1 (en) | Gene therapy for hearing disorders | |
| EM88007260006S (en) | Hearing aids for the deaf (part of -) | |
| EM88007260007S (de) | Hörhilfen für Schwerhörige (Teil von -) | |
| EM88007260008S (pt) | Aparelhos auditivos para surdez (parte de -) | |
| EM88007260003S (fi) | Kuulolaitteet kuulovammaisille (osa -) | |
| EM87901580004S (ro) | Aparate auditive pentru surzi (Părţi de -) | |
| EM87901580002S (lv) | Dzirdes aparāti kurlajiem (- daļa) | |
| EM87901580007S (da) | Høreapparater til døve (del af -) | |
| EM87901580001S (lv) | Dzirdes aparāti kurlajiem (- daļa) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A00 | Application filed |
Free format text: ST27 STATUS EVENT CODE: A-0-1-A10-A00-A101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: APPLICATION RECEIVED - PCT Effective date: 20250128 |
|
| MFA | Maintenance fee for application paid |
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|
| W00 | Other event occurred |
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|
| W00 | Other event occurred |
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|
| A15 | Pct application entered into the national or regional phase |
Free format text: ST27 STATUS EVENT CODE: A-1-1-A10-A15-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: NATIONAL ENTRY REQUIREMENTS DETERMINED COMPLIANT Effective date: 20250506 |
|
| P18 | Priority claim added or amended |
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| P13 | Application amended |
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| MFA | Maintenance fee for application paid |
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| U00 | Fee paid |
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