CA3254727A1 - PSYCHOACTIVE MEDICINES AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC AND NEUROLOGICAL DISORDERS AND DISORDERS - Google Patents

PSYCHOACTIVE MEDICINES AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC AND NEUROLOGICAL DISORDERS AND DISORDERS

Info

Publication number
CA3254727A1
CA3254727A1 CA3254727A CA3254727A CA3254727A1 CA 3254727 A1 CA3254727 A1 CA 3254727A1 CA 3254727 A CA3254727 A CA 3254727A CA 3254727 A CA3254727 A CA 3254727A CA 3254727 A1 CA3254727 A1 CA 3254727A1
Authority
CA
Canada
Prior art keywords
disorder
methylone
disorders
anxiety
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3254727A
Other languages
English (en)
French (fr)
Inventor
Blake MANDELL
Martin Stogniew
Jennifer Louise SCHMIDT
Markus SEELIG
Original Assignee
Transcend Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2022/074369 external-priority patent/WO2023015154A1/en
Application filed by Transcend Therapeutics Inc filed Critical Transcend Therapeutics Inc
Publication of CA3254727A1 publication Critical patent/CA3254727A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA3254727A 2022-03-31 2023-02-02 PSYCHOACTIVE MEDICINES AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC AND NEUROLOGICAL DISORDERS AND DISORDERS Pending CA3254727A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202263325757P 2022-03-31 2022-03-31
US63/325,757 2022-03-31
US202263328343P 2022-04-07 2022-04-07
US63/328,343 2022-04-07
USPCT/US2022/074369 2022-08-01
PCT/US2022/074369 WO2023015154A1 (en) 2021-08-06 2022-08-01 Psychoactive medicines and their use for treating psychiatric and neurological conditions and disorders
US202363437000P 2023-01-04 2023-01-04
US63/437,000 2023-01-04
PCT/US2023/012196 WO2023191952A1 (en) 2022-03-31 2023-02-02 Psychoactive medicines and their use for treating psychiatric and neurological conditions and disorders

Publications (1)

Publication Number Publication Date
CA3254727A1 true CA3254727A1 (en) 2023-10-05

Family

ID=88203364

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3254727A Pending CA3254727A1 (en) 2022-03-31 2023-02-02 PSYCHOACTIVE MEDICINES AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC AND NEUROLOGICAL DISORDERS AND DISORDERS

Country Status (10)

Country Link
EP (1) EP4499066A4 (https=)
JP (1) JP2025510790A (https=)
KR (1) KR20240165982A (https=)
CN (1) CN119095593A (https=)
AU (1) AU2023241546A1 (https=)
CA (1) CA3254727A1 (https=)
IL (1) IL315832A (https=)
MX (1) MX2024012095A (https=)
TW (1) TW202345789A (https=)
WO (1) WO2023191952A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120379978A (zh) * 2022-10-20 2025-07-25 创见疗法股份有限公司 苯乙胺和卡西酮及其立体异构体与其前体的制备

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996039133A1 (en) * 1995-06-06 1996-12-12 Neurobiological Technologies, Inc. Novel n-substituted-2-amino-3',4'-methylene-dioxypropiophenones
US8575194B1 (en) * 2004-08-31 2013-11-05 Jack William Schultz Treatment methods of cognitive, emotional and mental ailments and disorders
EP2931291B1 (en) * 2012-12-11 2021-10-20 The McLean Hospital Corporation Xenon treatment as an adjunct to psychotherapy for psychiatric disorders
WO2017151980A1 (en) * 2016-03-03 2017-09-08 Segreti Louis M Cannabis-based bioactive formulations and methods for use thereof
WO2021257500A1 (en) * 2020-06-17 2021-12-23 Lobe Sciences Ltd. Methods and compositions for treating mild traumatic brain injury, post-traumatic stress disorder and mild traumatic brain injury with post traumatic stress disorder
JP2024512796A (ja) * 2021-04-01 2024-03-19 テラン バイオサイエンシーズ インク. サイケデリック薬およびセロトニン受容体調節因子に関する方法と組成物
MX2024001654A (es) * 2021-08-06 2024-06-28 Transcend Therapeutics Inc Medicamentos psicoactivos y su uso para el tratamiento de enfermedades y trastornos psiquiatricos y neurologicos.
AU2022330718B2 (en) * 2021-08-20 2026-02-19 Pharmala Biotech Inc. Compositions comprising non-racemic mixtures of (r)- and (s)-3,4-methylenedioxymethamphetamine or (r) and (s) n-methyl-1,3-benzodioxolylbutanamine and uses thereof
WO2023081899A1 (en) * 2021-11-05 2023-05-11 Terran Biosciences, Inc. Isotopically enriched n-methyl-1,3-benzodioxolylbutanamine (mbdb) and stereoisomers thereof
EP4426685A4 (en) * 2021-11-05 2026-01-07 Terran Biosciences Inc Isotopic salts, crystalline forms, stereoisomers of methylone and ethylone and their methods of use
CA3239514A1 (en) * 2021-12-09 2023-06-15 Matthew J. Baggott Specialized combinations for mental disorders or mental enhancement

Also Published As

Publication number Publication date
MX2024012095A (es) 2025-01-09
KR20240165982A (ko) 2024-11-25
IL315832A (en) 2024-11-01
CN119095593A (zh) 2024-12-06
WO2023191952A1 (en) 2023-10-05
JP2025510790A (ja) 2025-04-15
TW202345789A (zh) 2023-12-01
EP4499066A4 (en) 2026-02-18
AU2023241546A1 (en) 2024-10-17
EP4499066A1 (en) 2025-02-05

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