CA3244873A1 - Preventive treatment for migraines - Google Patents

Preventive treatment for migraines

Info

Publication number
CA3244873A1
CA3244873A1 CA3244873A CA3244873A CA3244873A1 CA 3244873 A1 CA3244873 A1 CA 3244873A1 CA 3244873 A CA3244873 A CA 3244873A CA 3244873 A CA3244873 A CA 3244873A CA 3244873 A1 CA3244873 A1 CA 3244873A1
Authority
CA
Canada
Prior art keywords
atogepant
treatment
migraine
baseline
days
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3244873A
Other languages
English (en)
French (fr)
Inventor
Joel Trugman
Michelle Finnegan
Original Assignee
Allergan Pharmaceuticals International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Pharmaceuticals International Ltd filed Critical Allergan Pharmaceuticals International Ltd
Publication of CA3244873A1 publication Critical patent/CA3244873A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA3244873A 2022-03-09 2023-03-09 Preventive treatment for migraines Pending CA3244873A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202263269105P 2022-03-09 2022-03-09
US63/269,105 2022-03-09
US202263347265P 2022-05-31 2022-05-31
US63/347,265 2022-05-31
US202263404352P 2022-09-07 2022-09-07
US63/404,352 2022-09-07
US202363480365P 2023-01-18 2023-01-18
US63/480,365 2023-01-18
PCT/US2023/064027 WO2023173005A2 (en) 2022-03-09 2023-03-09 Preventive treatment of migraine

Publications (1)

Publication Number Publication Date
CA3244873A1 true CA3244873A1 (en) 2023-09-14

Family

ID=87936018

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3244873A Pending CA3244873A1 (en) 2022-03-09 2023-03-09 Preventive treatment for migraines

Country Status (8)

Country Link
US (1) US20230321055A1 (https=)
EP (1) EP4489856A4 (https=)
JP (1) JP2025508004A (https=)
CN (1) CN119421710A (https=)
AU (1) AU2023231645A1 (https=)
CA (1) CA3244873A1 (https=)
MX (1) MX2024010878A (https=)
WO (1) WO2023173005A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12168004B2 (en) 2014-02-05 2024-12-17 Merck Sharp & Dohme Llc Treatment of migraine
US12383545B1 (en) 2018-06-08 2025-08-12 Allergan Pharmaceuticals International Limited Treatment of migraine
CN116390712A (zh) 2020-07-29 2023-07-04 阿勒根制药国际有限公司 治疗偏头痛
CA3206184A1 (en) 2020-12-22 2022-06-30 Allergan Pharmaceuticals International Limited Treatment of migraine
EP4408418A1 (en) 2021-09-27 2024-08-07 Allergan Pharmaceuticals International Limited Combination comprising atogepant for treating migraine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190374520A1 (en) * 2018-06-08 2019-12-12 Allergan Pharmaceuticals International Limited Treatment of migraine
US20210121541A1 (en) * 2019-07-05 2021-04-29 Allergan Pharmaceuticals International Limited CGRP Antagonists and Clostridial Derivatives for the Treatment of Neuropsychiatric and Neurological Disorders
CN116390712A (zh) * 2020-07-29 2023-07-04 阿勒根制药国际有限公司 治疗偏头痛

Also Published As

Publication number Publication date
US20230321055A1 (en) 2023-10-12
JP2025508004A (ja) 2025-03-21
CN119421710A (zh) 2025-02-11
WO2023173005A2 (en) 2023-09-14
MX2024010878A (es) 2024-09-17
WO2023173005A3 (en) 2023-11-23
EP4489856A4 (en) 2026-04-15
AU2023231645A1 (en) 2024-09-12
EP4489856A2 (en) 2025-01-15

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