CA3240896A1 - Uses of bicyclic compounds for the treatment of diseases - Google Patents

Uses of bicyclic compounds for the treatment of diseases

Info

Publication number
CA3240896A1
CA3240896A1 CA3240896A CA3240896A CA3240896A1 CA 3240896 A1 CA3240896 A1 CA 3240896A1 CA 3240896 A CA3240896 A CA 3240896A CA 3240896 A CA3240896 A CA 3240896A CA 3240896 A1 CA3240896 A1 CA 3240896A1
Authority
CA
Canada
Prior art keywords
compound
alkyl
mmol
halo
membered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3240896A
Other languages
English (en)
French (fr)
Inventor
Leen Kawas
Kevin Church
Robert Taylor
Jewel JOHNSTON
Douglas Boatman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Athira Pharma Inc
Original Assignee
Athira Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Athira Pharma Inc filed Critical Athira Pharma Inc
Publication of CA3240896A1 publication Critical patent/CA3240896A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA3240896A 2021-12-17 2022-12-16 Uses of bicyclic compounds for the treatment of diseases Pending CA3240896A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163290783P 2021-12-17 2021-12-17
US63/290,783 2021-12-17
US202263312696P 2022-02-22 2022-02-22
US63/312,696 2022-02-22
PCT/US2022/053113 WO2023114456A1 (en) 2021-12-17 2022-12-16 Uses of bicyclic compounds for the treatment of diseases

Publications (1)

Publication Number Publication Date
CA3240896A1 true CA3240896A1 (en) 2023-06-22

Family

ID=86773494

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3240896A Pending CA3240896A1 (en) 2021-12-17 2022-12-16 Uses of bicyclic compounds for the treatment of diseases

Country Status (11)

Country Link
US (1) US20250041307A1 (https=)
EP (1) EP4448100A4 (https=)
JP (1) JP2024546600A (https=)
KR (1) KR20240121239A (https=)
AU (1) AU2022410646A1 (https=)
CA (1) CA3240896A1 (https=)
CL (1) CL2024001748A1 (https=)
IL (1) IL313039A (https=)
MX (1) MX2024005884A (https=)
TW (1) TW202339756A (https=)
WO (1) WO2023114456A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025515045A (ja) * 2022-05-04 2025-05-13 アティラ・ファーマ・インコーポレイテッド 神経炎症病態を治療する方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6184223B1 (en) * 1995-10-27 2001-02-06 Molecumetics Ltd. Reverse-turn mimetics and methods relating thereto
AU2003284120A1 (en) * 2002-10-17 2004-05-04 Myriad Genetics, Inc. Reverse-turn mimetics and composition and methods relating thereto
EP2155226A4 (en) * 2007-06-14 2010-07-28 Univ California COMPOUNDS FOR INHIBITING THE PROTEIN AGGREGATION AND METHOD FOR THE PRODUCTION AND USE THEREOF
KR20130139895A (ko) * 2010-09-02 2013-12-23 다케다 야쿠힌 고교 가부시키가이샤 경도인지 장애의 치료 또는 예방용 융합 트리아졸
CA2817975C (en) * 2010-11-16 2020-03-31 Michael Kahn Cbp/catenin antagonists for enhancing asymmetric division of somatic stem cells
AP2014007606A0 (en) * 2011-10-07 2014-05-31 Takeda Pharmaceutical 1-Arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases
CN119684295A (zh) * 2020-11-02 2025-03-25 雅斯娜制药公司 用于治疗疾病的双环化合物及其用途

Also Published As

Publication number Publication date
CL2024001748A1 (es) 2024-11-22
WO2023114456A1 (en) 2023-06-22
TW202339756A (zh) 2023-10-16
KR20240121239A (ko) 2024-08-08
EP4448100A4 (en) 2025-10-22
US20250041307A1 (en) 2025-02-06
IL313039A (en) 2024-07-01
MX2024005884A (es) 2024-05-29
AU2022410646A1 (en) 2024-05-30
JP2024546600A (ja) 2024-12-26
EP4448100A1 (en) 2024-10-23

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