CA3234642A1 - Transposases et leurs utilisations - Google Patents
Transposases et leurs utilisations Download PDFInfo
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- CA3234642A1 CA3234642A1 CA3234642A CA3234642A CA3234642A1 CA 3234642 A1 CA3234642 A1 CA 3234642A1 CA 3234642 A CA3234642 A CA 3234642A CA 3234642 A CA3234642 A CA 3234642A CA 3234642 A1 CA3234642 A1 CA 3234642A1
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- transposase
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- fusion protein
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
- C07K2319/81—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/90—Vectors containing a transposable element
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
La présente divulgation concerne d'une manière générale des domaines de transposases, en particulier des domaines de transposases comprenant des délétions amino-terminales, ainsi que des domaines de transposases formant des hétérodimères obligatoires et des domaines de transposases comprenant des domaines de ciblage d'ADN.
Applications Claiming Priority (7)
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US202163252028P | 2021-10-04 | 2021-10-04 | |
US63/252,028 | 2021-10-04 | ||
US202263312928P | 2022-02-23 | 2022-02-23 | |
US63/312,928 | 2022-02-23 | ||
US202263369863P | 2022-07-29 | 2022-07-29 | |
US63/369,863 | 2022-07-29 | ||
PCT/US2022/077549 WO2023060089A2 (fr) | 2021-10-04 | 2022-10-04 | Transposases et leurs utilisations |
Publications (1)
Publication Number | Publication Date |
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CA3234642A1 true CA3234642A1 (fr) | 2023-04-13 |
Family
ID=84045028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3234642A Pending CA3234642A1 (fr) | 2021-10-04 | 2022-10-04 | Transposases et leurs utilisations |
Country Status (7)
Country | Link |
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EP (1) | EP4413124A2 (fr) |
JP (1) | JP2024536307A (fr) |
KR (1) | KR20240099249A (fr) |
AU (1) | AU2022358729A1 (fr) |
CA (1) | CA3234642A1 (fr) |
IL (1) | IL311782A (fr) |
WO (1) | WO2023060089A2 (fr) |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
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US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
US4656134A (en) | 1982-01-11 | 1987-04-07 | Board Of Trustees Of Leland Stanford Jr. University | Gene amplification in eukaryotic cells |
US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
US4766067A (en) | 1985-05-31 | 1988-08-23 | President And Fellows Of Harvard College | Gene amplification |
GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
US4889818A (en) | 1986-08-22 | 1989-12-26 | Cetus Corporation | Purified thermostable enzyme |
US4921794A (en) | 1987-01-14 | 1990-05-01 | President And Fellows Of Harvard College | T7 DNA polymerase |
US4795699A (en) | 1987-01-14 | 1989-01-03 | President And Fellows Of Harvard College | T7 DNA polymerase |
US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
US5091310A (en) | 1988-09-23 | 1992-02-25 | Cetus Corporation | Structure-independent dna amplification by the polymerase chain reaction |
US5066584A (en) | 1988-09-23 | 1991-11-19 | Cetus Corporation | Methods for generating single stranded dna by the polymerase chain reaction |
US5142033A (en) | 1988-09-23 | 1992-08-25 | Hoffmann-La Roche Inc. | Structure-independent DNA amplification by the polymerase chain reaction |
US4994370A (en) | 1989-01-03 | 1991-02-19 | The United States Of America As Represented By The Department Of Health And Human Services | DNA amplification technique |
US5266491A (en) | 1989-03-14 | 1993-11-30 | Mochida Pharmaceutical Co., Ltd. | DNA fragment and expression plasmid containing the DNA fragment |
US5580575A (en) | 1989-12-22 | 1996-12-03 | Imarx Pharmaceutical Corp. | Therapeutic drug delivery systems |
US5580734A (en) | 1990-07-13 | 1996-12-03 | Transkaryotic Therapies, Inc. | Method of producing a physical map contigous DNA sequences |
US5641670A (en) | 1991-11-05 | 1997-06-24 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
US5968502A (en) | 1991-11-05 | 1999-10-19 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
US5643252A (en) | 1992-10-28 | 1997-07-01 | Venisect, Inc. | Laser perforator |
US5730723A (en) | 1995-10-10 | 1998-03-24 | Visionary Medical Products Corporation, Inc. | Gas pressured needle-less injection device and method |
US6218185B1 (en) | 1996-04-19 | 2001-04-17 | The United States Of America As Represented By The Secretary Of Agriculture | Piggybac transposon-based genetic transformation system for insects |
US5827729A (en) | 1996-04-23 | 1998-10-27 | Advanced Tissue Sciences | Diffusion gradient bioreactor and extracorporeal liver device using a three-dimensional liver tissue |
US6962810B2 (en) | 2000-10-31 | 2005-11-08 | University Of Notre Dame Du Lac | Methods and compositions for transposition using minimal segments of the eukaryotic transformation vector piggyBac |
EP4442820A2 (fr) | 2009-02-26 | 2024-10-09 | Poseida Therapeutics, Inc. | Transposases piggybac hyperactives |
SG10201607943RA (en) * | 2012-03-23 | 2016-11-29 | Cellectis | Method to overcome dna chemical modifications sensitivity of engineered tale dna binding domains |
US10927384B2 (en) | 2014-04-09 | 2021-02-23 | Dna Twopointo Inc. | DNA vectors, transposons and transposases for eukaryotic genome modification |
WO2019049816A1 (fr) | 2017-09-05 | 2019-03-14 | 東レ株式会社 | Moulages de résine thermoplastique renforcée par des fibres |
WO2019173636A1 (fr) | 2018-03-07 | 2019-09-12 | Poseida Therapeutics, Inc. | Compositions de cartyrin et méthodes d'utilisation |
BR112021020143A2 (pt) * | 2019-04-08 | 2021-12-14 | Dna Twopointo Inc | Integração de construções de ácidos nucleicos com células eucarióticas com uma transposase de oryzias |
JP2022540318A (ja) * | 2019-06-11 | 2022-09-15 | ウニベルシタット ポンペウ ファブラ | 標的遺伝子編集構築物およびそれを使用する方法 |
-
2022
- 2022-10-04 JP JP2024519988A patent/JP2024536307A/ja active Pending
- 2022-10-04 KR KR1020247014862A patent/KR20240099249A/ko unknown
- 2022-10-04 AU AU2022358729A patent/AU2022358729A1/en active Pending
- 2022-10-04 CA CA3234642A patent/CA3234642A1/fr active Pending
- 2022-10-04 IL IL311782A patent/IL311782A/en unknown
- 2022-10-04 EP EP22798022.4A patent/EP4413124A2/fr active Pending
- 2022-10-04 WO PCT/US2022/077549 patent/WO2023060089A2/fr active Application Filing
Also Published As
Publication number | Publication date |
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WO2023060089A3 (fr) | 2023-05-25 |
KR20240099249A (ko) | 2024-06-28 |
IL311782A (en) | 2024-05-01 |
EP4413124A2 (fr) | 2024-08-14 |
WO2023060089A2 (fr) | 2023-04-13 |
JP2024536307A (ja) | 2024-10-04 |
AU2022358729A1 (en) | 2024-04-11 |
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