CA3229395A1 - Nucleotide complexes capable of an improved dna synthesis yield - Google Patents

Nucleotide complexes capable of an improved dna synthesis yield Download PDF

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Publication number
CA3229395A1
CA3229395A1 CA3229395A CA3229395A CA3229395A1 CA 3229395 A1 CA3229395 A1 CA 3229395A1 CA 3229395 A CA3229395 A CA 3229395A CA 3229395 A CA3229395 A CA 3229395A CA 3229395 A1 CA3229395 A1 CA 3229395A1
Authority
CA
Canada
Prior art keywords
nucleotide
dna
complex
complexes
polyatomic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3229395A
Other languages
English (en)
French (fr)
Inventor
Daniel KYSH
Paul ROTHWELL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Touchlight IP Ltd
Original Assignee
Touchlight IP Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Touchlight IP Ltd filed Critical Touchlight IP Ltd
Publication of CA3229395A1 publication Critical patent/CA3229395A1/en
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA3229395A 2021-08-16 2022-08-16 Nucleotide complexes capable of an improved dna synthesis yield Pending CA3229395A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2111742.9 2021-08-16
GBGB2111742.9A GB202111742D0 (en) 2021-08-16 2021-08-16 Improved process
PCT/GB2022/052132 WO2023021286A2 (en) 2021-08-16 2022-08-16 Novel nucleotide complexes capable of an improved dna yield

Publications (1)

Publication Number Publication Date
CA3229395A1 true CA3229395A1 (en) 2023-02-23

Family

ID=77860040

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3229395A Pending CA3229395A1 (en) 2021-08-16 2022-08-16 Nucleotide complexes capable of an improved dna synthesis yield

Country Status (9)

Country Link
US (1) US20250136636A1 (https=)
EP (1) EP4388117A2 (https=)
JP (1) JP2024532148A (https=)
KR (1) KR20240047441A (https=)
CN (1) CN118103520A (https=)
AU (1) AU2022331143A1 (https=)
CA (1) CA3229395A1 (https=)
GB (1) GB202111742D0 (https=)
WO (1) WO2023021286A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202319998D0 (en) 2023-12-22 2024-02-07 Touchlight Ip Ltd duplexing method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201415789D0 (en) * 2014-09-05 2014-10-22 Touchlight Genetics Ltd Synthesis of DNA
GB201813429D0 (en) * 2018-08-17 2018-10-03 Touchlight Ip Ltd Synthesis of DNA with improved yield
GB202002068D0 (en) * 2020-02-14 2020-04-01 Touchlight Ip Ltd DNA synthesis yield improvements

Also Published As

Publication number Publication date
WO2023021286A2 (en) 2023-02-23
GB202111742D0 (en) 2021-09-29
US20250136636A1 (en) 2025-05-01
CN118103520A (zh) 2024-05-28
AU2022331143A1 (en) 2024-02-29
EP4388117A2 (en) 2024-06-26
WO2023021286A3 (en) 2023-06-01
JP2024532148A (ja) 2024-09-05
KR20240047441A (ko) 2024-04-12

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