CA3229059A1 - Traitement de la cephalee vasculaire de horton a l'aide d'anticorps anti-cgrp - Google Patents
Traitement de la cephalee vasculaire de horton a l'aide d'anticorps anti-cgrp Download PDFInfo
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- CA3229059A1 CA3229059A1 CA3229059A CA3229059A CA3229059A1 CA 3229059 A1 CA3229059 A1 CA 3229059A1 CA 3229059 A CA3229059 A CA 3229059A CA 3229059 A CA3229059 A CA 3229059A CA 3229059 A1 CA3229059 A1 CA 3229059A1
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Neurosurgery (AREA)
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- Biophysics (AREA)
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- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne des méthodes de traitement de la céphalée vasculaire de Horton comprenant l'administration d'un anticorps antagoniste anti-CGRP à un patient nécessitant un tel traitement.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202163237639P | 2021-08-27 | 2021-08-27 | |
US63/237,639 | 2021-08-27 | ||
PCT/IB2022/058002 WO2023026245A1 (fr) | 2021-08-27 | 2022-08-26 | Traitement de la céphalée vasculaire de horton à l'aide d'anticorps anti-cgrp |
Publications (1)
Publication Number | Publication Date |
---|---|
CA3229059A1 true CA3229059A1 (fr) | 2023-03-02 |
Family
ID=83188745
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CA3229059A Pending CA3229059A1 (fr) | 2021-08-27 | 2022-08-26 | Traitement de la cephalee vasculaire de horton a l'aide d'anticorps anti-cgrp |
Country Status (6)
Country | Link |
---|---|
KR (1) | KR20240049275A (fr) |
CN (1) | CN117813325A (fr) |
AU (1) | AU2022333323A1 (fr) |
CA (1) | CA3229059A1 (fr) |
IL (1) | IL310885A (fr) |
WO (1) | WO2023026245A1 (fr) |
Family Cites Families (40)
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US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
US6548640B1 (en) | 1986-03-27 | 2003-04-15 | Btg International Limited | Altered antibodies |
AU600575B2 (en) | 1987-03-18 | 1990-08-16 | Sb2, Inc. | Altered antibodies |
GB8725529D0 (en) | 1987-10-30 | 1987-12-02 | Delta Biotechnology Ltd | Polypeptides |
ATE135370T1 (de) | 1988-12-22 | 1996-03-15 | Kirin Amgen Inc | Chemisch modifizierte granulocytenkolonie erregender faktor |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US5766883A (en) | 1989-04-29 | 1998-06-16 | Delta Biotechnology Limited | Polypeptides |
FR2650598B1 (fr) | 1989-08-03 | 1994-06-03 | Rhone Poulenc Sante | Derives de l'albumine a fonction therapeutique |
US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
FR2669336B1 (fr) | 1990-11-20 | 1993-01-22 | Adir | Nouveaux derives d'oxazolo pyridines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
US6407213B1 (en) | 1991-06-14 | 2002-06-18 | Genentech, Inc. | Method for making humanized antibodies |
WO1994004679A1 (fr) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Procede pour fabriquer des anticorps humanises |
FR2686899B1 (fr) | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
US5604260A (en) | 1992-12-11 | 1997-02-18 | Merck Frosst Canada Inc. | 5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2 |
US5409944A (en) | 1993-03-12 | 1995-04-25 | Merck Frosst Canada, Inc. | Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase |
AU6445894A (en) | 1993-03-19 | 1994-10-11 | Duke University | Method of treatment of tumors with an antibody binding to tenascin |
US5474995A (en) | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
US5436265A (en) | 1993-11-12 | 1995-07-25 | Merck Frosst Canada, Inc. | 1-aroyl-3-indolyl alkanoic acids and derivatives thereof useful as anti-inflammatory agents |
US5643575A (en) | 1993-10-27 | 1997-07-01 | Enzon, Inc. | Non-antigenic branched polymer conjugates |
US5475995A (en) | 1994-05-16 | 1995-12-19 | Livingston; George G. | Truck spare tire locking rod |
US5616601A (en) | 1994-07-28 | 1997-04-01 | Gd Searle & Co | 1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation |
CA2195557C (fr) | 1994-08-12 | 2006-10-17 | Shui-On Leung | Immunoconjugues et anticorps de type humain specifiques contre des lymphomes malins a cellules b et des cellules leucemiques |
US5521213A (en) | 1994-08-29 | 1996-05-28 | Merck Frosst Canada, Inc. | Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2 |
US5593994A (en) | 1994-09-29 | 1997-01-14 | The Dupont Merck Pharmaceutical Company | Prostaglandin synthase inhibitors |
US5552422A (en) | 1995-01-11 | 1996-09-03 | Merck Frosst Canada, Inc. | Aryl substituted 5,5 fused aromatic nitrogen compounds as anti-inflammatory agents |
US5604253A (en) | 1995-05-22 | 1997-02-18 | Merck Frosst Canada, Inc. | N-benzylindol-3-yl propanoic acid derivatives as cyclooxygenase inhibitors |
US5639780A (en) | 1995-05-22 | 1997-06-17 | Merck Frosst Canada, Inc. | N-benzyl indol-3-yl butanoic acid derivatives as cyclooxygenase inhibitors |
US5510368A (en) | 1995-05-22 | 1996-04-23 | Merck Frosst Canada, Inc. | N-benzyl-3-indoleacetic acids as antiinflammatory drugs |
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NZ597767A (en) | 2007-05-21 | 2013-06-28 | Bristol Myers Squibb Co | Antibodies to IL-6 and use thereof |
TW201531484A (zh) | 2007-05-21 | 2015-08-16 | Alder Biopharmaceuticals Inc | 抗TNF-α之抗體及其用途 |
BR112013029959A8 (pt) * | 2011-05-20 | 2021-09-08 | Alderbio Holdings Llc | Anticorpos anti-cgrp e anti-cgrpr e seu uso para prevenir ou inibir fotofobia ou aversão à luz, composição farmacêutica compreendendo os referidos anticorpos, bem como sequência de ácido nucleico e célula recombinante |
HUE044062T2 (hu) | 2011-05-20 | 2019-09-30 | Alderbio Holdings Llc | Anti-CGRP készítmények és alkalmazásuk |
AU2012258976B8 (en) | 2011-05-20 | 2017-07-20 | H. Lundbeck A/S | Use of anti-CGRP or anti-CGRP-R antibodies or antibody fragments to treat or prevent chronic and acute forms of diarrhea |
TWI712419B (zh) | 2013-07-03 | 2020-12-11 | 美商艾爾德生物製藥股份有限公司 | 使用抗cgrp抗體之葡萄糖代謝的調節 |
SG11202106878XA (en) * | 2019-01-08 | 2021-07-29 | H Lundbeck As | Treatment of medication overuse headache using anti-cgrp or anti-cgrp-r antibodies |
SG11202110637RA (en) * | 2019-05-02 | 2021-10-28 | H Lundbeck As | Treatment of headache using anti-cgrp antibodies |
AU2020355233A1 (en) * | 2019-09-25 | 2022-05-19 | Allergan Pharmaceuticals International Limited | Combination therapy with CGRP antagonists |
-
2022
- 2022-08-26 CA CA3229059A patent/CA3229059A1/fr active Pending
- 2022-08-26 CN CN202280056361.0A patent/CN117813325A/zh active Pending
- 2022-08-26 AU AU2022333323A patent/AU2022333323A1/en active Pending
- 2022-08-26 IL IL310885A patent/IL310885A/en unknown
- 2022-08-26 KR KR1020247005340A patent/KR20240049275A/ko unknown
- 2022-08-26 WO PCT/IB2022/058002 patent/WO2023026245A1/fr active Application Filing
Also Published As
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AU2022333323A1 (en) | 2024-02-29 |
IL310885A (en) | 2024-04-01 |
CN117813325A (zh) | 2024-04-02 |
WO2023026245A1 (fr) | 2023-03-02 |
KR20240049275A (ko) | 2024-04-16 |
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