CA3227486A1 - Domaines et echafaudages vnar desimmunises - Google Patents
Domaines et echafaudages vnar desimmunises Download PDFInfo
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- CA3227486A1 CA3227486A1 CA3227486A CA3227486A CA3227486A1 CA 3227486 A1 CA3227486 A1 CA 3227486A1 CA 3227486 A CA3227486 A CA 3227486A CA 3227486 A CA3227486 A CA 3227486A CA 3227486 A1 CA3227486 A1 CA 3227486A1
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Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La présente invention concerne des échafaudages VNAR désimmunisés, des procédés de fabrication des échafaudages et leur utilisation en tant que structures, et des domaines VNAR comprenant ces échafaudages, en particulier des domaines VNAR thérapeutiques à un antigène cible d'intérêt, comprenant, par exemple, des domaines VNAR à haute affinité qui présentent une réaction croisée avec les récepteurs de la transferrine (TfR) de primate ainsi que d'autres domaines VNAR susceptibles de transporter une charge thérapeutique ou diagnostique à travers la barrière hémato-encéphalique.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202163234210P | 2021-08-17 | 2021-08-17 | |
US63/234,210 | 2021-08-17 | ||
US202163277590P | 2021-11-09 | 2021-11-09 | |
US63/277,590 | 2021-11-09 | ||
PCT/US2022/040616 WO2023023166A1 (fr) | 2021-08-17 | 2022-08-17 | Domaines et échafaudages vnar désimmunisés |
Publications (1)
Publication Number | Publication Date |
---|---|
CA3227486A1 true CA3227486A1 (fr) | 2023-02-23 |
Family
ID=89722117
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3227486A Pending CA3227486A1 (fr) | 2021-08-17 | 2022-08-17 | Domaines et echafaudages vnar desimmunises |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA3227486A1 (fr) |
-
2022
- 2022-08-17 CA CA3227486A patent/CA3227486A1/fr active Pending
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