CA3213904A1 - Composition for preventing or treating neurodegenerative disease comprising compounds that induces the expression of anti-aging gene klotho - Google Patents
Composition for preventing or treating neurodegenerative disease comprising compounds that induces the expression of anti-aging gene klotho Download PDFInfo
- Publication number
- CA3213904A1 CA3213904A1 CA3213904A CA3213904A CA3213904A1 CA 3213904 A1 CA3213904 A1 CA 3213904A1 CA 3213904 A CA3213904 A CA 3213904A CA 3213904 A CA3213904 A CA 3213904A CA 3213904 A1 CA3213904 A1 CA 3213904A1
- Authority
- CA
- Canada
- Prior art keywords
- chemical formula
- straight
- branched alkyl
- arylamide
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2021-0042958 | 2021-04-01 | ||
| KR20210042958 | 2021-04-01 | ||
| KR10-2021-0130307 | 2021-09-30 | ||
| KR1020210130307A KR102375097B1 (ko) | 2021-04-01 | 2021-09-30 | 항노화 유전자 klotho의 발현을 유도하는 화합물을 포함하는 퇴행성 신경질환의 예방 또는 치료용 조성물 |
| PCT/KR2022/004341 WO2022211420A1 (ko) | 2021-04-01 | 2022-03-28 | 항노화 유전자 klotho의 발현을 유도하는 화합물을 포함하는 퇴행성 신경질환의 예방 또는 치료용 조성물 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3213904A1 true CA3213904A1 (en) | 2022-10-06 |
Family
ID=80936324
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3213904A Pending CA3213904A1 (en) | 2021-04-01 | 2022-03-28 | Composition for preventing or treating neurodegenerative disease comprising compounds that induces the expression of anti-aging gene klotho |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240358683A1 (https=) |
| EP (1) | EP4316487A4 (https=) |
| JP (1) | JP7728031B2 (https=) |
| KR (1) | KR102375097B1 (https=) |
| CN (1) | CN117136055A (https=) |
| AU (1) | AU2022251900B2 (https=) |
| BR (1) | BR112023019984A2 (https=) |
| CA (1) | CA3213904A1 (https=) |
| WO (1) | WO2022211420A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102375097B1 (ko) * | 2021-04-01 | 2022-03-17 | 주식회사 클로소사이언스 | 항노화 유전자 klotho의 발현을 유도하는 화합물을 포함하는 퇴행성 신경질환의 예방 또는 치료용 조성물 |
| JP7728030B2 (ja) * | 2021-04-01 | 2025-08-22 | クロトー サイエンシーズ カンパニー リミテッド | 抗老化遺伝子ｋｌｏｔｈｏの発現を誘導する化合物を含む慢性腎疾患の予防または治療用組成物 |
| EP4434534A1 (en) | 2023-03-22 | 2024-09-25 | ADvantage Therapeutics, Inc. | Klotho mrna |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4088770A (en) * | 1971-05-04 | 1978-05-09 | Eli Lilly And Company | Substituted 2-anilinobenzoxazoles used as immunosuppressive agents |
| US6713474B2 (en) * | 1998-09-18 | 2004-03-30 | Abbott Gmbh & Co. Kg | Pyrrolopyrimidines as therapeutic agents |
| EP1388341A1 (en) * | 2002-08-07 | 2004-02-11 | Aventis Pharma Deutschland GmbH | Acylamino-substituted heteroaromatic compounds and their use as pharmaceuticals |
| US20070066577A1 (en) * | 2003-04-03 | 2007-03-22 | Hea Young Park Choo | Benzoxazole derivative or analogue thereof for inhibiting 5-lipoxygenase and pharmaceutical composition containing same |
| JP2008506686A (ja) | 2004-07-16 | 2008-03-06 | ザ トラスティーズ オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク | ベータ−アミロイドペプチドの形成を阻害することによるアルツハイマー病治療用化合物及び製造 |
| EP1910385B1 (en) * | 2005-08-04 | 2013-07-24 | Sirtris Pharmaceuticals, Inc. | Benzothiazoles and thiazolopyridines as sirtuin modulators |
| WO2010039186A2 (en) * | 2008-09-23 | 2010-04-08 | Renovis, Inc. | Compounds useful as faah modulators and uses thereof |
| WO2010129954A1 (en) * | 2009-05-08 | 2010-11-11 | Apogee Biotechnology Corporation | Treatment of ischemia-reperfusion injury |
| KR101372721B1 (ko) * | 2010-06-18 | 2014-03-14 | 이화여자대학교 산학협력단 | Ｉｎｔｅｒｌｅｕｋｉｎ―６ 억제 작용을 갖는 신규한 벤즈옥사졸 유도체, 이의 제조 방법 및 이를 포함하는 약학적 조성물 |
| KR101446301B1 (ko) * | 2013-04-11 | 2014-10-06 | 서울대학교산학협력단 | Cxcr3/cxcl10 길항제 화합물, 이의 제조방법 및 이를 포함하는 골 전이의 예방 및 치료용 약학 조성물 |
| KR20160069736A (ko) * | 2014-12-09 | 2016-06-17 | (주)아모레퍼시픽 | 메틸화된 카테킨을 유효성분으로 함유하는 Klotho 유전자 활성화용 조성물 |
| US10647689B2 (en) | 2015-04-28 | 2020-05-12 | Sanford Burnham Prebys Medical Discovery Institute | Apelin receptor agonists and methods of use thereof |
| KR101770310B1 (ko) * | 2015-08-24 | 2017-08-24 | 이화여자대학교 산학협력단 | 2-(페닐아미노)벤조[d]옥사졸-5-올 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 염증성 질환의 예방 또는 치료용 약학적 조성물 |
| KR102064611B1 (ko) * | 2017-10-13 | 2020-01-09 | 이화여자대학교 산학협력단 | 벤즈옥사졸 유도체, 이의 제조 방법 및 이를 포함하는 약학적 조성물 |
| KR102522955B1 (ko) | 2018-09-26 | 2023-04-19 | 미쓰비시 덴키 빌딩 솔루션즈 가부시키가이샤 | 엘리베이터 시스템 및 휴대 단말 |
| JP7412546B2 (ja) | 2019-10-02 | 2024-01-12 | 克洛索科学公司 | 抗老化遺伝子ｋｌｏｔｈｏの発現を誘導する化合物およびその用途 |
| KR102749973B1 (ko) | 2020-04-21 | 2025-01-06 | 엘지마그나 이파워트레인 주식회사 | 전기모터 및 이를 구비한 전기차량 |
| KR102375097B1 (ko) * | 2021-04-01 | 2022-03-17 | 주식회사 클로소사이언스 | 항노화 유전자 klotho의 발현을 유도하는 화합물을 포함하는 퇴행성 신경질환의 예방 또는 치료용 조성물 |
-
2021
- 2021-09-30 KR KR1020210130307A patent/KR102375097B1/ko active Active
-
2022
- 2022-03-28 CN CN202280026649.3A patent/CN117136055A/zh active Pending
- 2022-03-28 EP EP22781539.6A patent/EP4316487A4/en active Pending
- 2022-03-28 JP JP2023561185A patent/JP7728031B2/ja active Active
- 2022-03-28 WO PCT/KR2022/004341 patent/WO2022211420A1/ko not_active Ceased
- 2022-03-28 BR BR112023019984A patent/BR112023019984A2/pt unknown
- 2022-03-28 CA CA3213904A patent/CA3213904A1/en active Pending
- 2022-03-28 AU AU2022251900A patent/AU2022251900B2/en active Active
- 2022-03-28 US US18/553,414 patent/US20240358683A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4316487A1 (en) | 2024-02-07 |
| CN117136055A (zh) | 2023-11-28 |
| JP7728031B2 (ja) | 2025-08-22 |
| AU2022251900B2 (en) | 2025-09-18 |
| US20240358683A1 (en) | 2024-10-31 |
| EP4316487A4 (en) | 2025-04-09 |
| JP2024512818A (ja) | 2024-03-19 |
| AU2022251900A9 (en) | 2023-11-09 |
| AU2022251900A1 (en) | 2023-10-26 |
| WO2022211420A1 (ko) | 2022-10-06 |
| BR112023019984A2 (pt) | 2024-04-02 |
| KR102375097B1 (ko) | 2022-03-17 |
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