CA3212248A1 - Improved methods of treating diseases resulting from a maladapted stress response - Google Patents

Improved methods of treating diseases resulting from a maladapted stress response Download PDF

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Publication number
CA3212248A1
CA3212248A1 CA3212248A CA3212248A CA3212248A1 CA 3212248 A1 CA3212248 A1 CA 3212248A1 CA 3212248 A CA3212248 A CA 3212248A CA 3212248 A CA3212248 A CA 3212248A CA 3212248 A1 CA3212248 A1 CA 3212248A1
Authority
CA
Canada
Prior art keywords
crfr2
agonist
maladaptation
ct38s
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3212248A
Other languages
English (en)
French (fr)
Inventor
Gerard PEREIRA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cortene Inc
Original Assignee
Cortene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cortene Inc filed Critical Cortene Inc
Publication of CA3212248A1 publication Critical patent/CA3212248A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2228Corticotropin releasing factor [CRF] (Urotensin)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
CA3212248A 2021-03-17 2022-03-17 Improved methods of treating diseases resulting from a maladapted stress response Pending CA3212248A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163200609P 2021-03-17 2021-03-17
US63/200,609 2021-03-17
PCT/US2022/071209 WO2022198230A1 (en) 2021-03-17 2022-03-17 Improved methods of treating diseases resulting from a maladapted stress response

Publications (1)

Publication Number Publication Date
CA3212248A1 true CA3212248A1 (en) 2022-09-22

Family

ID=83320930

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3212248A Pending CA3212248A1 (en) 2021-03-17 2022-03-17 Improved methods of treating diseases resulting from a maladapted stress response

Country Status (6)

Country Link
US (1) US20250319161A1 (https=)
EP (1) EP4308150A4 (https=)
JP (1) JP2024511066A (https=)
AU (1) AU2022238570A1 (https=)
CA (1) CA3212248A1 (https=)
WO (1) WO2022198230A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117618528B (zh) * 2023-12-01 2024-10-01 广东医科大学 一种方格星虫多肽srp及其在制备治疗急性肾损伤药物中的应用
TW202544027A (zh) * 2024-04-19 2025-11-16 美商紐羅克里生物科學有限公司 促皮質素釋放因子受體2(crfr2)促效劑

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110105397A1 (en) * 2009-11-04 2011-05-05 Gengo Peter J Method for treating heart failure with stresscopin-like peptides
KR20190084055A (ko) * 2016-10-20 2019-07-15 코르텐 인코포레이티드 부적응 스트레스 반응에서 기인한 질환의 치료 방법

Also Published As

Publication number Publication date
AU2022238570A1 (en) 2023-09-28
EP4308150A4 (en) 2025-02-19
US20250319161A1 (en) 2025-10-16
JP2024511066A (ja) 2024-03-12
WO2022198230A1 (en) 2022-09-22
EP4308150A1 (en) 2024-01-24

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