CA3208771A1 - Systems, devices, and methods for harmonization of imaging datasets including biomarkers - Google Patents

Systems, devices, and methods for harmonization of imaging datasets including biomarkers Download PDF

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Publication number
CA3208771A1
CA3208771A1 CA3208771A CA3208771A CA3208771A1 CA 3208771 A1 CA3208771 A1 CA 3208771A1 CA 3208771 A CA3208771 A CA 3208771A CA 3208771 A CA3208771 A CA 3208771A CA 3208771 A1 CA3208771 A1 CA 3208771A1
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Prior art keywords
neuromelanin
data
mri
dataset
coefficients
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Pending
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CA3208771A
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English (en)
French (fr)
Inventor
Samuel CLARK
Kenneth WENGLER
Guillermo HORGA HERNANDEZ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University in the City of New York
Research Foundation for Mental Hygiene Inc
Terran Biosciences Inc
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Columbia University in the City of New York
Research Foundation for Mental Hygiene Inc
Terran Biosciences Inc
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Application filed by Columbia University in the City of New York, Research Foundation for Mental Hygiene Inc, Terran Biosciences Inc filed Critical Columbia University in the City of New York
Publication of CA3208771A1 publication Critical patent/CA3208771A1/en
Pending legal-status Critical Current

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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5608—Data processing and visualization specially adapted for MR, e.g. for feature analysis and pattern recognition on the basis of measured MR data, segmentation of measured MR data, edge contour detection on the basis of measured MR data, for enhancing measured MR data in terms of signal-to-noise ratio by means of noise filtering or apodization, for enhancing measured MR data in terms of resolution by means for deblurring, windowing, zero filling, or generation of gray-scaled images, colour-coded images or images displaying vectors instead of pixels
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00—Image enhancement or restoration
    • G06T5/50—Image enhancement or restoration using two or more images, e.g. averaging or subtraction
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00—Image enhancement or restoration
    • G06T5/90—Dynamic range modification of images or parts thereof
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G06T7/0014—Biomedical image inspection using an image reference approach
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H15/00—ICT specially adapted for medical reports, e.g. generation or transmission thereof
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/70—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mental therapies, e.g. psychological therapy or autogenous training
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H70/00—ICT specially adapted for the handling or processing of medical references
    • G16H70/20—ICT specially adapted for the handling or processing of medical references relating to practices or guidelines
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10072—Tomographic images
    • G06T2207/10088—Magnetic resonance imaging [MRI]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/20—Special algorithmic details
    • G06T2207/20081—Training; Learning
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30016—Brain

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Theoretical Computer Science (AREA)
  • Data Mining & Analysis (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Databases & Information Systems (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Quality & Reliability (AREA)
  • Artificial Intelligence (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Signal Processing (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychology (AREA)
  • Social Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Developmental Disabilities (AREA)
  • Bioethics (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Image Analysis (AREA)
CA3208771A 2021-03-11 2022-03-11 Systems, devices, and methods for harmonization of imaging datasets including biomarkers Pending CA3208771A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163159915P 2021-03-11 2021-03-11
US63/159,915 2021-03-11
PCT/US2022/020036 WO2022192728A2 (en) 2021-03-11 2022-03-11 Systems, devices, and methods for harmonization of imaging datasets including biomarkers

Publications (1)

Publication Number Publication Date
CA3208771A1 true CA3208771A1 (en) 2022-09-15

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CA3208771A Pending CA3208771A1 (en) 2021-03-11 2022-03-11 Systems, devices, and methods for harmonization of imaging datasets including biomarkers

Country Status (10)

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US (1) US12079960B2 (https=)
EP (1) EP4304470A4 (https=)
JP (1) JP2024510080A (https=)
KR (1) KR20230156903A (https=)
CN (1) CN117098496A (https=)
AU (1) AU2022232517A1 (https=)
CA (1) CA3208771A1 (https=)
IL (1) IL305267A (https=)
MX (1) MX2023009703A (https=)
WO (1) WO2022192728A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117098496A (zh) 2021-03-11 2023-11-21 人类生物科学股份有限公司 用于协调包括生物标志物的成像数据集的系统、装置和方法
US12450792B2 (en) * 2022-03-28 2025-10-21 Shanghai United Imaging Healthcare Co., Ltd. Systems and methods for MRI data processing
WO2025051988A1 (en) 2023-09-08 2025-03-13 Quibim S.L. Computer implemented method and computer programs for harmonization of magnetic resonance images
CN118070985B (zh) * 2024-04-24 2024-07-16 国网江西省电力有限公司南昌供电分公司 一种预测配电自动化终端验收时间的方法

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JP2002510537A (ja) 1998-04-08 2002-04-09 ザ ジェネラル ホスピタル コーポレーション 薬理検査用ｍｒｉ（ｐｈｍｒｉ）
JP4228048B2 (ja) 2000-10-09 2009-02-25 ピーオーダブリューエムアールアイ リミテッド 神経変性障害の検出方法
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US20070275944A1 (en) 2006-04-05 2007-11-29 The Board Of Trustees Operating Michigan State University Antioxidants and methods of their use
EP3251670A1 (en) 2007-08-06 2017-12-06 Biotie Therapies, Inc. Methods for treating dependence
WO2014071359A1 (en) 2012-11-05 2014-05-08 Msdx, Inc. Detection of neurological diseases via measurement of neuromelanin in recirculating phagocytes
EP2470250A4 (en) 2009-08-25 2013-07-17 Univ California OPTIMIZED PLACEMENT OF CANNULAS FOR THE ADMINISTRATION OF THERAPY AGENTS IN THE BRAIN
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US20150023877A1 (en) 2013-07-18 2015-01-22 The Board Of Trustees Of The Leland Stanford Junior University Methods of parkinsons disease diagnosis and monitoring treatment
KR102245189B1 (ko) 2014-03-06 2021-04-28 삼성메디슨 주식회사 의료 영상 처리 장치 및 그에 따른 의료 영상 처리 방법
US10194829B2 (en) 2015-07-07 2019-02-05 Q Bio, Inc. Fast scanning based on magnetic resonance history
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WO2017192952A1 (en) 2016-05-05 2017-11-09 The Medical College Of Wisconsin, Inc. Voxelwise spectral profile modeling for use in multispectral magnetic resonance imaging
US12471153B2 (en) * 2016-06-19 2025-11-11 Platform Science, Inc. Method and system for synchronizing events within a secure wireless network
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JP2022508684A (ja) 2018-10-10 2022-01-19 ザ トラスティーズ オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク ヒトの脳におけるドーパミン機能の非侵襲的代理測定としての神経メラニン感受性磁気共鳴画像法のためのシステム、方法及びコンピュータアクセス可能媒体
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CN117098496A (zh) 2021-03-11 2023-11-21 人类生物科学股份有限公司 用于协调包括生物标志物的成像数据集的系统、装置和方法

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AU2022232517A9 (en) 2024-05-16
US20220292657A1 (en) 2022-09-15
KR20230156903A (ko) 2023-11-15
JP2024510080A (ja) 2024-03-06
WO2022192728A2 (en) 2022-09-15
MX2023009703A (es) 2023-08-29
IL305267A (en) 2023-10-01
US12079960B2 (en) 2024-09-03
EP4304470A4 (en) 2025-01-15
EP4304470A2 (en) 2024-01-17
AU2022232517A1 (en) 2023-08-17
WO2022192728A3 (en) 2022-10-27
CN117098496A (zh) 2023-11-21

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