CA3208189A1 - Methods for treating familial chylomicronemia syndrome - Google Patents
Methods for treating familial chylomicronemia syndrome Download PDFInfo
- Publication number
- CA3208189A1 CA3208189A1 CA3208189A CA3208189A CA3208189A1 CA 3208189 A1 CA3208189 A1 CA 3208189A1 CA 3208189 A CA3208189 A CA 3208189A CA 3208189 A CA3208189 A CA 3208189A CA 3208189 A1 CA3208189 A1 CA 3208189A1
- Authority
- CA
- Canada
- Prior art keywords
- patient
- lomitapide
- dosing period
- dose
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163155960P | 2021-03-03 | 2021-03-03 | |
| US63/155,960 | 2021-03-03 | ||
| US202163165457P | 2021-03-24 | 2021-03-24 | |
| US63/165,457 | 2021-03-24 | ||
| PCT/US2022/018672 WO2022187463A1 (en) | 2021-03-03 | 2022-03-03 | Methods for treating familial chylomicronemia syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3208189A1 true CA3208189A1 (en) | 2022-09-09 |
Family
ID=80819670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3208189A Pending CA3208189A1 (en) | 2021-03-03 | 2022-03-03 | Methods for treating familial chylomicronemia syndrome |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240165093A1 (https=) |
| EP (1) | EP4301361A1 (https=) |
| JP (1) | JP2024508334A (https=) |
| KR (1) | KR20230153375A (https=) |
| AU (1) | AU2022231007A1 (https=) |
| BR (1) | BR112023016943A2 (https=) |
| CA (1) | CA3208189A1 (https=) |
| IL (1) | IL305191A (https=) |
| MX (1) | MX2023010297A (https=) |
| WO (1) | WO2022187463A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3186856A1 (en) | 2020-07-29 | 2022-02-03 | Ruth NALLEN | Lomitapide for use in methods of treating hyperlipidemia and hypercholesterolemia in pediatric patients |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5595872A (en) | 1992-03-06 | 1997-01-21 | Bristol-Myers Squibb Company | Nucleic acids encoding microsomal trigyceride transfer protein |
| US5883109A (en) | 1996-07-24 | 1999-03-16 | Bristol-Myers Squibb Company | Method for lowering serum lipid levels employing an MTP inhibitor in combination with another cholesterol lowering drug |
| US6066653A (en) | 1997-01-17 | 2000-05-23 | Bristol-Myers Squibb Co. | Method of treating acid lipase deficiency diseases with an MTP inhibitor and cholesterol lowering drugs |
| KR101494067B1 (ko) | 2004-03-05 | 2015-02-16 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 부작용을 최소화하면서 과지질혈증 및 과콜레스테롤혈증과 연관된 질환 또는 질병의 치료 방법 |
| BR102015025502B1 (pt) | 2015-04-30 | 2022-06-21 | Aegerion Pharmaceuticals, Inc | Composição de lomitapida, tablete, produto de lomitapida, métodos para analisar uma composição de amostra de lomitapida e para determinar uma quantidade de uma impureza em uma amostra da composição |
-
2022
- 2022-03-03 CA CA3208189A patent/CA3208189A1/en active Pending
- 2022-03-03 AU AU2022231007A patent/AU2022231007A1/en active Pending
- 2022-03-03 MX MX2023010297A patent/MX2023010297A/es unknown
- 2022-03-03 BR BR112023016943A patent/BR112023016943A2/pt unknown
- 2022-03-03 JP JP2023553354A patent/JP2024508334A/ja active Pending
- 2022-03-03 IL IL305191A patent/IL305191A/en unknown
- 2022-03-03 EP EP22711788.4A patent/EP4301361A1/en active Pending
- 2022-03-03 US US18/548,798 patent/US20240165093A1/en active Pending
- 2022-03-03 WO PCT/US2022/018672 patent/WO2022187463A1/en not_active Ceased
- 2022-03-03 KR KR1020237028890A patent/KR20230153375A/ko active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL305191A (en) | 2023-10-01 |
| BR112023016943A2 (pt) | 2023-10-31 |
| US20240165093A1 (en) | 2024-05-23 |
| AU2022231007A9 (en) | 2024-09-19 |
| AU2022231007A1 (en) | 2023-08-17 |
| KR20230153375A (ko) | 2023-11-06 |
| MX2023010297A (es) | 2023-09-12 |
| JP2024508334A (ja) | 2024-02-26 |
| EP4301361A1 (en) | 2024-01-10 |
| WO2022187463A1 (en) | 2022-09-09 |
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