CA3206400A1 - .gamma..delta. t cells derived from induced pluripotent stem cells, and production method therefor - Google Patents

.gamma..delta. t cells derived from induced pluripotent stem cells, and production method therefor Download PDF

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Publication number
CA3206400A1
CA3206400A1 CA3206400A CA3206400A CA3206400A1 CA 3206400 A1 CA3206400 A1 CA 3206400A1 CA 3206400 A CA3206400 A CA 3206400A CA 3206400 A CA3206400 A CA 3206400A CA 3206400 A1 CA3206400 A1 CA 3206400A1
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cells
cell
derived
ips
differentiation induction
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English (en)
French (fr)
Inventor
Takashi Aoi
Nobuyuki Murai
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Kobe University NUC
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Kobe University NUC
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/421—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32—T-cell receptors [TCR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00—Antineoplastic agents
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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CA3206400A 2021-02-05 2022-02-04 .gamma..delta. t cells derived from induced pluripotent stem cells, and production method therefor Pending CA3206400A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021-017831 2021-02-05
JP2021017831 2021-02-05
PCT/JP2022/004542 WO2022168959A1 (ja) 2021-02-05 2022-02-04 人工多能性幹細胞由来γδＴ細胞及びその作製方法

Publications (1)

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CA3206400A1 true CA3206400A1 (en) 2022-08-11

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CA3206400A Pending CA3206400A1 (en) 2021-02-05 2022-02-04 .gamma..delta. t cells derived from induced pluripotent stem cells, and production method therefor

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US (2) US20240100093A1 (https=)
EP (1) EP4289940A4 (https=)
JP (2) JP7793209B2 (https=)
KR (1) KR20230128324A (https=)
CN (1) CN116964194A (https=)
CA (1) CA3206400A1 (https=)
WO (1) WO2022168959A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025111392A (ja) * 2023-12-28 2025-07-30 財團法人工業技術研究院 幹細胞から分化する免疫細胞を作製するための方法およびキット
CN118421559B (zh) * 2024-07-04 2024-09-27 成都赛济元生物医药有限公司 定向分化淋巴造血前体细胞的小分子组合、试剂盒及方法

Family Cites Families (14)

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Publication number Priority date Publication date Assignee Title
GB191404423A (en) 1914-02-20 1914-07-02 Gustav Albert Schulz Improved Bottle-stopper.
FR2215700B1 (https=) 1973-01-26 1976-05-14 Thomson Csf
JPS5412679A (en) 1977-06-30 1979-01-30 Nec Home Electronics Ltd Manufacture of semiconductor device
JPS5479790A (en) 1977-12-06 1979-06-26 Hirohisa Nagashima Method of attaching pouring beak to container and container with pouring beak
JPWO2011096482A1 (ja) 2010-02-03 2013-06-13 国立大学法人 東京大学 多能性幹細胞を用いた免疫機能再建法
WO2014165707A2 (en) 2013-04-03 2014-10-09 Memorial Sloan-Kettering Cancer Center Effective generation of tumor-targeted t-cells derived from pluripotent stem cells
AU2015290561A1 (en) 2014-07-18 2017-03-09 Hiroshi Kawamoto Method for generating pluripotent stem cells bearing antigen specific T cell receptor genes
JPWO2016010153A1 (ja) 2014-07-18 2017-04-27 宏 河本 免疫細胞療法用ｔ細胞の誘導方法
JP7224021B2 (ja) * 2017-02-03 2023-02-17 国立大学法人神戸大学 人工多能性幹細胞の作製方法
EP3580332B1 (en) * 2017-02-07 2026-04-15 Agency for Science, Technology And Research Methods and kits for generating mimetic innate immune cells from pluripotent stem cells
CA3091158A1 (en) * 2018-02-14 2019-08-22 Sunnybrook Research Institute Method for generating cells of the t cell lineage
TW202020145A (zh) * 2018-07-13 2020-06-01 國立大學法人京都大學 γδＴ細胞的製造方法
JP7265948B2 (ja) 2019-07-18 2023-04-27 株式会社小松製作所 予測装置、予測方法および作業車両
BR112023018844A2 (pt) * 2021-04-07 2023-10-10 Century Therapeutics Inc Composições e métodos para geração de células t gama-delta de células-tronco pluripotentes induzidas

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Publication number Publication date
US20250213693A1 (en) 2025-07-03
EP4289940A4 (en) 2025-02-26
US12576149B2 (en) 2026-03-17
JP7793209B2 (ja) 2026-01-05
CN116964194A (zh) 2023-10-27
EP4289940A1 (en) 2023-12-13
KR20230128324A (ko) 2023-09-04
JP2025163076A (ja) 2025-10-28
JPWO2022168959A1 (https=) 2022-08-11
US20240100093A1 (en) 2024-03-28
WO2022168959A1 (ja) 2022-08-11

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