CA3206312A1 - Chimeric receptor binding proteins resistant to proteolytic degradation - Google Patents

Chimeric receptor binding proteins resistant to proteolytic degradation

Info

Publication number
CA3206312A1
CA3206312A1 CA3206312A CA3206312A CA3206312A1 CA 3206312 A1 CA3206312 A1 CA 3206312A1 CA 3206312 A CA3206312 A CA 3206312A CA 3206312 A CA3206312 A CA 3206312A CA 3206312 A1 CA3206312 A1 CA 3206312A1
Authority
CA
Canada
Prior art keywords
virus
protein
chimeric
rbp
syn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3206312A
Other languages
English (en)
French (fr)
Inventor
Jesus Fernandez Rodriguez
Xavier DUPORTET
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eligo Bioscience
Original Assignee
Eligo Bioscience
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2020/088043 external-priority patent/WO2021136812A1/en
Application filed by Eligo Bioscience filed Critical Eligo Bioscience
Priority claimed from PCT/EP2021/087775 external-priority patent/WO2022144382A1/en
Publication of CA3206312A1 publication Critical patent/CA3206312A1/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/73Expression systems using phage (lambda) regulatory sequences
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10111Myoviridae
    • C12N2795/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10111Myoviridae
    • C12N2795/10151Methods of production or purification of viral material
    • C12N2795/10152Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10311Siphoviridae
    • C12N2795/10341Use of virus, viral particle or viral elements as a vector
    • C12N2795/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
CA3206312A 2020-12-30 2021-12-29 Chimeric receptor binding proteins resistant to proteolytic degradation Pending CA3206312A1 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US202063132190P 2020-12-30 2020-12-30
US202063132090P 2020-12-30 2020-12-30
US63/132,190 2020-12-30
US17/138,084 2020-12-30
PCT/EP2020/088043 WO2021136812A1 (en) 2019-12-30 2020-12-30 Bacterial delivery vehicles for in vivo delivery of a dna payload
US17/138,084 US20210196828A1 (en) 2019-12-30 2020-12-30 Bacterial delivery vehicles for in vivo delivery of a dna payload
US63/132,090 2020-12-30
EPPCT/EP2020/088043 2020-12-30
US202163137989P 2021-01-15 2021-01-15
US63/137,989 2021-01-15
PCT/EP2021/087775 WO2022144382A1 (en) 2020-12-30 2021-12-29 Chimeric receptor binding proteins resistant to proteolytic degradation

Publications (1)

Publication Number Publication Date
CA3206312A1 true CA3206312A1 (en) 2022-07-07

Family

ID=87424019

Family Applications (2)

Application Number Title Priority Date Filing Date
CA3206312A Pending CA3206312A1 (en) 2020-12-30 2021-12-29 Chimeric receptor binding proteins resistant to proteolytic degradation
CA3205876A Pending CA3205876A1 (en) 2020-12-30 2021-12-29 Microbiome modulation of a host by delivery of dna payloads with minimized spread

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA3205876A Pending CA3205876A1 (en) 2020-12-30 2021-12-29 Microbiome modulation of a host by delivery of dna payloads with minimized spread

Country Status (5)

Country Link
EP (2) EP4271809A1 (ja)
JP (2) JP2024501870A (ja)
KR (2) KR20230128506A (ja)
CA (2) CA3206312A1 (ja)
IL (2) IL304050A (ja)

Also Published As

Publication number Publication date
JP2024501870A (ja) 2024-01-16
KR20230128506A (ko) 2023-09-05
EP4271808A1 (en) 2023-11-08
IL304020A (en) 2023-08-01
EP4271809A1 (en) 2023-11-08
IL304050A (en) 2023-08-01
CA3205876A1 (en) 2022-07-07
JP2024501871A (ja) 2024-01-16
KR20230127265A (ko) 2023-08-31

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