CA3206312A1 - Chimeric receptor binding proteins resistant to proteolytic degradation - Google Patents
Chimeric receptor binding proteins resistant to proteolytic degradationInfo
- Publication number
- CA3206312A1 CA3206312A1 CA3206312A CA3206312A CA3206312A1 CA 3206312 A1 CA3206312 A1 CA 3206312A1 CA 3206312 A CA3206312 A CA 3206312A CA 3206312 A CA3206312 A CA 3206312A CA 3206312 A1 CA3206312 A1 CA 3206312A1
- Authority
- CA
- Canada
- Prior art keywords
- virus
- protein
- chimeric
- rbp
- syn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/73—Expression systems using phage (lambda) regulatory sequences
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10111—Myoviridae
- C12N2795/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10111—Myoviridae
- C12N2795/10151—Methods of production or purification of viral material
- C12N2795/10152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10311—Siphoviridae
- C12N2795/10341—Use of virus, viral particle or viral elements as a vector
- C12N2795/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
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- Microbiology (AREA)
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- Physics & Mathematics (AREA)
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- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063132190P | 2020-12-30 | 2020-12-30 | |
US202063132090P | 2020-12-30 | 2020-12-30 | |
US63/132,190 | 2020-12-30 | ||
US17/138,084 | 2020-12-30 | ||
PCT/EP2020/088043 WO2021136812A1 (en) | 2019-12-30 | 2020-12-30 | Bacterial delivery vehicles for in vivo delivery of a dna payload |
US17/138,084 US20210196828A1 (en) | 2019-12-30 | 2020-12-30 | Bacterial delivery vehicles for in vivo delivery of a dna payload |
US63/132,090 | 2020-12-30 | ||
EPPCT/EP2020/088043 | 2020-12-30 | ||
US202163137989P | 2021-01-15 | 2021-01-15 | |
US63/137,989 | 2021-01-15 | ||
PCT/EP2021/087775 WO2022144382A1 (en) | 2020-12-30 | 2021-12-29 | Chimeric receptor binding proteins resistant to proteolytic degradation |
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CA3206312A1 true CA3206312A1 (en) | 2022-07-07 |
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CA3205876A Pending CA3205876A1 (en) | 2020-12-30 | 2021-12-29 | Microbiome modulation of a host by delivery of dna payloads with minimized spread |
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CA3205876A Pending CA3205876A1 (en) | 2020-12-30 | 2021-12-29 | Microbiome modulation of a host by delivery of dna payloads with minimized spread |
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EP (2) | EP4271809A1 (ja) |
JP (2) | JP2024501870A (ja) |
KR (2) | KR20230128506A (ja) |
CA (2) | CA3206312A1 (ja) |
IL (2) | IL304050A (ja) |
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JP2024501870A (ja) | 2024-01-16 |
KR20230128506A (ko) | 2023-09-05 |
EP4271808A1 (en) | 2023-11-08 |
IL304020A (en) | 2023-08-01 |
EP4271809A1 (en) | 2023-11-08 |
IL304050A (en) | 2023-08-01 |
CA3205876A1 (en) | 2022-07-07 |
JP2024501871A (ja) | 2024-01-16 |
KR20230127265A (ko) | 2023-08-31 |
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