CA3194798A1 - Inhibiteurs d'osteoclastes contre la douleur - Google Patents

Inhibiteurs d'osteoclastes contre la douleur

Info

Publication number
CA3194798A1
CA3194798A1 CA3194798A CA3194798A CA3194798A1 CA 3194798 A1 CA3194798 A1 CA 3194798A1 CA 3194798 A CA3194798 A CA 3194798A CA 3194798 A CA3194798 A CA 3194798A CA 3194798 A1 CA3194798 A1 CA 3194798A1
Authority
CA
Canada
Prior art keywords
zoledronic acid
pain
compound
administered
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3194798A
Other languages
English (en)
Inventor
Herriot TABUTEAU
Eric K. M. Dinkla
Graeme Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antecip Bioventures II LLC
Original Assignee
Antecip Bioventures II LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/288,720 external-priority patent/US8865757B1/en
Priority claimed from US14/288,716 external-priority patent/US8835650B1/en
Priority claimed from US14/310,811 external-priority patent/US8822436B1/en
Priority claimed from PCT/US2014/050427 external-priority patent/WO2015060924A1/fr
Priority claimed from US14/457,659 external-priority patent/US20140349974A1/en
Priority claimed from US14/495,732 external-priority patent/US9127069B1/en
Priority claimed from US14/530,556 external-priority patent/US20150051175A1/en
Priority claimed from US14/536,526 external-priority patent/US20150057250A1/en
Priority claimed from US14/604,524 external-priority patent/US9211257B2/en
Priority claimed from US14/608,855 external-priority patent/US9079927B1/en
Priority claimed from US14/625,457 external-priority patent/US9427403B2/en
Priority claimed from US14/639,013 external-priority patent/US9289441B2/en
Application filed by Antecip Bioventures II LLC filed Critical Antecip Bioventures II LLC
Publication of CA3194798A1 publication Critical patent/CA3194798A1/fr
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA3194798A 2014-05-27 2015-05-27 Inhibiteurs d'osteoclastes contre la douleur Pending CA3194798A1 (fr)

Applications Claiming Priority (55)

Application Number Priority Date Filing Date Title
US201414228241A 2014-05-27 2014-05-27
US14/228,241 2014-05-27
US14/288,720 2014-05-28
US14/288,713 2014-05-28
US14/288,720 US8865757B1 (en) 2014-05-28 2014-05-28 Therapeutic compositions comprising imidazole and imidazolium compounds
US14/288,716 US8835650B1 (en) 2014-01-30 2014-05-28 Substituted imidazolium compounds for treating disease
US14/288,713 US8901162B1 (en) 2014-01-30 2014-05-28 Substituted imidazolium compounds for treating disease
US14/288,716 2014-05-28
US201462012112P 2014-06-13 2014-06-13
US62/012,112 2014-06-13
US14/310,811 US8822436B1 (en) 2012-05-14 2014-06-20 Compositions for oral administration of zoledronic acid or related compounds for treating disease
US14/310,811 2014-06-20
US14/336,642 US20140329773A1 (en) 2012-05-14 2014-07-21 Compositions for Oral Administration of Zoledronic Acid or Related Compounds for Treating Disease
US14/336,642 2014-07-21
US14/446,184 2014-07-29
US14/446,184 US9006279B1 (en) 2014-01-30 2014-07-29 Substituted imidazolium compounds for treating disease
PCT/US2014/050427 WO2015060924A1 (fr) 2013-10-25 2014-08-08 Compositions pour administration orale d'acide zolédronique ou de composés associés pour le traitement de maladies
USPCT/US2014/050427 2014-08-08
US14/457,659 2014-08-12
US14/457,659 US20140349974A1 (en) 2014-08-12 2014-08-12 Zoledronic acid dosage forms for the treatment of pain
US14/481,097 US8962599B1 (en) 2014-05-27 2014-09-09 Therapeutic compositions comprising imidazole and imidazolium compounds
US14/481,097 2014-09-09
US201462053619P 2014-09-22 2014-09-22
US62/053,619 2014-09-22
US14/495,732 2014-09-24
US14/495,732 US9127069B1 (en) 2014-06-11 2014-09-24 Compositions comprising rank/rankl antagonists and related compounds for treating pain
US14/530,556 2014-10-31
US14/530,556 US20150051175A1 (en) 2012-05-14 2014-10-31 Co-Administration of Steroids and Zoledronic Acid to Prevent and Treat Pain
US14/536,526 US20150057250A1 (en) 2012-05-14 2014-11-07 Inhibitors of osteoclast activity for treating arthritis
US14/536,526 2014-11-07
US14/538,709 US9290575B2 (en) 2014-06-11 2014-11-11 Compositions comprising RANK/RANKL antagonists and related compounds for treating pain
US14/538,709 2014-11-11
US14/540,333 2014-11-13
US14/540,333 US9216168B1 (en) 2014-05-27 2014-11-13 Therapeutic compositions comprising imidazole and imidazolium compounds
US14/604,524 2015-01-23
US14/604,524 US9211257B2 (en) 2012-05-14 2015-01-23 Osteoclast inhibitors for knee conditions
US14/605,822 2015-01-26
US14/605,822 US9216153B2 (en) 2012-05-14 2015-01-26 Osteoclast inhibitors for knee conditions
US14/607,947 2015-01-28
US14/607,985 2015-01-28
US14/607,947 US9289384B2 (en) 2012-05-14 2015-01-28 Osteoclast inhibitors for knee conditions
US14/607,985 US9289385B2 (en) 2012-05-14 2015-01-28 Osteoclast inhibitors for knee conditions
US14/608,855 2015-01-29
US14/608,855 US9079927B1 (en) 2014-05-27 2015-01-29 Substituted imidazolium compounds for treating disease
US14/625,457 2015-02-18
US14/625,457 US9427403B2 (en) 2012-05-14 2015-02-18 Methods for the safe administration of imidazole or imidazolium compounds
US201562127214P 2015-03-02 2015-03-02
US14/635,857 2015-03-02
US14/635,857 US9283239B2 (en) 2012-05-14 2015-03-02 Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US62/127,214 2015-03-02
US14/639,013 US9289441B2 (en) 2014-08-08 2015-03-04 Osteoclast inhibitors such as zoledronic acid for low back pain treatment
US14/639,013 2015-03-04
US14/686,551 2015-04-14
US14/686,551 US9408860B2 (en) 2012-05-14 2015-04-14 Compositions for oral administration of zoledronic acid or related compounds for treating low back pain
CA3114271A CA3114271C (fr) 2014-05-27 2015-05-27 Inhibiteurs d'osteoclastes contre la douleur

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA3114271A Division CA3114271C (fr) 2014-05-27 2015-05-27 Inhibiteurs d'osteoclastes contre la douleur

Publications (1)

Publication Number Publication Date
CA3194798A1 true CA3194798A1 (fr) 2015-12-03

Family

ID=57483086

Family Applications (3)

Application Number Title Priority Date Filing Date
CA3194798A Pending CA3194798A1 (fr) 2014-05-27 2015-05-27 Inhibiteurs d'osteoclastes contre la douleur
CA2950443A Abandoned CA2950443A1 (fr) 2014-05-27 2015-05-27 Inhibiteurs d'osteoclastes contre la douleur
CA3114271A Active CA3114271C (fr) 2014-05-27 2015-05-27 Inhibiteurs d'osteoclastes contre la douleur

Family Applications After (2)

Application Number Title Priority Date Filing Date
CA2950443A Abandoned CA2950443A1 (fr) 2014-05-27 2015-05-27 Inhibiteurs d'osteoclastes contre la douleur
CA3114271A Active CA3114271C (fr) 2014-05-27 2015-05-27 Inhibiteurs d'osteoclastes contre la douleur

Country Status (3)

Country Link
AU (3) AU2017213506B2 (fr)
CA (3) CA3194798A1 (fr)
MY (1) MY185481A (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2849758T1 (en) * 2012-05-14 2018-07-31 Anatecip Bioventures Ii Llc COMPOSITION CONTAINING ZOLEDORNIH ALI OR RELATED COMPOUNDS FOR THE PREPARATION OF INHALANE PATIENTS AND RELATED STATIONS

Also Published As

Publication number Publication date
CA3114271C (fr) 2023-06-06
AU2017213506B2 (en) 2017-09-07
AU2019204559A1 (en) 2019-07-18
AU2017272199A1 (en) 2017-12-21
CA3114271A1 (fr) 2015-12-03
AU2019204559B2 (en) 2020-04-16
AU2017213506A1 (en) 2017-08-31
AU2017272199B2 (en) 2019-03-28
MY185481A (en) 2021-05-19
CA2950443A1 (fr) 2015-12-03

Similar Documents

Publication Publication Date Title
US9694023B2 (en) Methods for the safe administration of imidazole or imidazolium compounds
US9895383B2 (en) Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9707245B2 (en) Neridronic acid for treating complex regional pain syndrome
US9770457B2 (en) Neridronic acid for treating bone marrow lesion
US9675626B2 (en) Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9700570B2 (en) Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9795622B2 (en) Neridronic acid for treating pain associated with a joint
US9662343B2 (en) Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9669040B2 (en) Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US20170079995A1 (en) Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
US20160331768A1 (en) Compositions for oral administration of zoledronic acid or related compounds for treating low back pain
US20170065625A1 (en) Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
US20170079996A1 (en) Osteoclast Inhibitors for Knee Conditions
US20170056427A1 (en) Dosage forms for oral administration of zoledronic acid or related compounds for treating disease
US20170065622A1 (en) Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US20170071960A1 (en) Osteoclast inhibitors for knee conditions
US20170049791A1 (en) Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain syndrome
US9623036B2 (en) Osteoclast inhibitors such as zoledronic acid for low back pain treatment
US9511081B2 (en) Osteoclast inhibitors for knee conditions
WO2015184003A1 (fr) Inhibiteurs d'ostéoclastes contre la douleur
AU2019204559B2 (en) Osteoclast inhibitors for pain
AU2015267046C1 (en) Osteoclast inhibitors for pain

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20230331

EEER Examination request

Effective date: 20230331

EEER Examination request

Effective date: 20230331

EEER Examination request

Effective date: 20230331