CA3193398A1 - Compositions et methodes de prevention et de traitement de lesion cutanee radique - Google Patents

Compositions et methodes de prevention et de traitement de lesion cutanee radique

Info

Publication number
CA3193398A1
CA3193398A1 CA3193398A CA3193398A CA3193398A1 CA 3193398 A1 CA3193398 A1 CA 3193398A1 CA 3193398 A CA3193398 A CA 3193398A CA 3193398 A CA3193398 A CA 3193398A CA 3193398 A1 CA3193398 A1 CA 3193398A1
Authority
CA
Canada
Prior art keywords
composition
fiasma
radiation
cri
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3193398A
Other languages
English (en)
Inventor
Reginald L. Hardy
Mitchell Brigell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rythera Therapeutics Inc
Original Assignee
Rythera Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rythera Therapeutics Inc filed Critical Rythera Therapeutics Inc
Publication of CA3193398A1 publication Critical patent/CA3193398A1/fr
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des compositions et des méthodes de traitement de lésion cutanée radique (CRI), notamment une dermatite radique et une proctopathie radique, à l'aide d'un ou de plusieurs inhibiteurs fonctionnels de la sphingomyélinase acide (FIASMA).
CA3193398A 2020-09-22 2021-09-22 Compositions et methodes de prevention et de traitement de lesion cutanee radique Pending CA3193398A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063081718P 2020-09-22 2020-09-22
US202063081547P 2020-09-22 2020-09-22
US63/081,718 2020-09-22
US63/081,547 2020-09-22
PCT/US2021/051583 WO2022066791A1 (fr) 2020-09-22 2021-09-22 Compositions et méthodes de prévention et de traitement de lésion cutanée radique

Publications (1)

Publication Number Publication Date
CA3193398A1 true CA3193398A1 (fr) 2022-03-31

Family

ID=80857195

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3193398A Pending CA3193398A1 (fr) 2020-09-22 2021-09-22 Compositions et methodes de prevention et de traitement de lesion cutanee radique

Country Status (7)

Country Link
EP (1) EP4217001A4 (fr)
JP (1) JP2023544448A (fr)
AU (1) AU2021349237A1 (fr)
CA (1) CA3193398A1 (fr)
IL (1) IL301530A (fr)
MX (1) MX2023003357A (fr)
WO (1) WO2022066791A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024064898A2 (fr) * 2022-09-22 2024-03-28 Rythera Therapeutics Inc. Compositions et méthodes de prévention et de traitement de lésion cutanée radique

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19621038A1 (de) * 1996-05-24 1997-11-27 Boehringer Ingelheim Kg Aminoguanidine, Verfahren zu ihrer Herstellung und Arzneimittel, die diese Verbindungen enthalten
US7250445B1 (en) * 2005-01-14 2007-07-31 Ehrenpreis Eli D Anti-oxidant suppository for treating radiation proctopathy and other anorectal disorders
CN101605763B (zh) * 2006-12-21 2016-03-09 彼得·麦卡勒姆癌症研究所 防辐射化合物及相关方法
WO2009051628A2 (fr) * 2007-09-06 2009-04-23 Arezou Petrie Dispositif de traitement transdermique et procédé
US9616006B2 (en) * 2007-10-10 2017-04-11 DermaMedics, LLC Methods and compositions for treating dermatological diseases and conditions
WO2013181338A1 (fr) * 2012-05-31 2013-12-05 Bloodcenter Research Foundation Procédés permettant de traiter et d'empêcher une lésion produite par rayonnement à l'aide des polypeptides de la protéine c activée
US20180050019A1 (en) * 2015-03-06 2018-02-22 Repoceuticals Aps Melatonin for Preventing and Treating Radiation Vaginitis and Proctitis

Also Published As

Publication number Publication date
MX2023003357A (es) 2023-06-30
AU2021349237A1 (en) 2023-06-08
JP2023544448A (ja) 2023-10-23
EP4217001A1 (fr) 2023-08-02
WO2022066791A1 (fr) 2022-03-31
IL301530A (en) 2023-05-01
EP4217001A4 (fr) 2024-04-24

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20230321

EEER Examination request

Effective date: 20230321

EEER Examination request

Effective date: 20230321

EEER Examination request

Effective date: 20230321