CA3180857A1 - Nitric oxide or nitric oxide releasing compositions for use in treating sars-cov and sars-cov-2 - Google Patents

Nitric oxide or nitric oxide releasing compositions for use in treating sars-cov and sars-cov-2

Info

Publication number
CA3180857A1
CA3180857A1 CA3180857A CA3180857A CA3180857A1 CA 3180857 A1 CA3180857 A1 CA 3180857A1 CA 3180857 A CA3180857 A CA 3180857A CA 3180857 A CA3180857 A CA 3180857A CA 3180857 A1 CA3180857 A1 CA 3180857A1
Authority
CA
Canada
Prior art keywords
acid
nitric oxide
nitrite
organic
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3180857A
Other languages
English (en)
French (fr)
Inventor
Hugh Semple Munro
Christopher Barry Wood
Nicholas David Boote
Chris Poll
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thirty Respiratory Ltd
Original Assignee
Thirty Respiratory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB2005987.9A external-priority patent/GB202005987D0/en
Priority claimed from GBGB2008288.9A external-priority patent/GB202008288D0/en
Application filed by Thirty Respiratory Ltd filed Critical Thirty Respiratory Ltd
Publication of CA3180857A1 publication Critical patent/CA3180857A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CA3180857A 2020-04-23 2021-04-19 Nitric oxide or nitric oxide releasing compositions for use in treating sars-cov and sars-cov-2 Pending CA3180857A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB2005987.9 2020-04-23
GBGB2005987.9A GB202005987D0 (en) 2020-04-23 2020-04-23 Methods and compositions for treating and combatting sars-cov and sars-cov-2
GB2008288.9 2020-06-02
GBGB2008288.9A GB202008288D0 (en) 2020-06-02 2020-06-02 Methods and compositions for treating and combatting sars-cov and sars-cov-2
PCT/GB2021/050935 WO2021214440A1 (en) 2020-04-23 2021-04-19 Nitric oxide or nitric oxide releasing compositions for use in treating sars-cov and sars-cov-2

Publications (1)

Publication Number Publication Date
CA3180857A1 true CA3180857A1 (en) 2021-10-28

Family

ID=75746956

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3180857A Pending CA3180857A1 (en) 2020-04-23 2021-04-19 Nitric oxide or nitric oxide releasing compositions for use in treating sars-cov and sars-cov-2

Country Status (9)

Country Link
US (1) US20240016831A1 (https=)
EP (1) EP4138795A1 (https=)
JP (1) JP2023526584A (https=)
CN (1) CN115884758A (https=)
AU (1) AU2021259360A1 (https=)
BR (1) BR112022021454A2 (https=)
CA (1) CA3180857A1 (https=)
GB (1) GB2610722B (https=)
WO (1) WO2021214440A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10517817B2 (en) 2013-05-09 2019-12-31 Syk Technologies, Llc Deep topical systemic nitric oxide therapy apparatus and method
ES2968200T3 (es) 2016-01-27 2024-05-08 Syk Tech Llc Aparato y métodos de aplicación tópica de óxido nítrico
EP4452219A2 (en) * 2021-12-22 2024-10-30 ConvaTec Limited Powder composition
WO2023118839A1 (en) * 2021-12-22 2023-06-29 Thirty Holdings Limited Powder composition
GB202215521D0 (en) * 2022-10-20 2022-12-07 Thirty Holdings Ltd Wound dressings
GB202302117D0 (en) * 2023-02-14 2023-03-29 Thirty Respiratory Ltd Compositions, kits and combinations
GB202302118D0 (en) * 2023-02-14 2023-03-29 Thirty Therapeutics Ltd Compositions, kits and combinations
US20260090985A1 (en) * 2024-10-02 2026-04-02 Aspire Biopharma Holdings, Inc. Oral mucosal formulations of aspirin

Family Cites Families (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3826255A (en) 1972-06-22 1974-07-30 Hudson Oxygen Therapy Sales Co Intermittent positive pressure breathing manifold
YU41046B (en) 1974-08-22 1986-10-31 Schering Ag Medicine inholating device
US4130639A (en) 1977-09-28 1978-12-19 Ethicon, Inc. Absorbable pharmaceutical compositions based on isomorphic copolyoxalates
US4268460A (en) 1977-12-12 1981-05-19 Warner-Lambert Company Nebulizer
US4253468A (en) 1978-08-14 1981-03-03 Steven Lehmbeck Nebulizer attachment
US4263907A (en) 1979-05-14 1981-04-28 Lindsey Joseph W Respirator nebulizer
US4510929A (en) 1982-04-30 1985-04-16 Bordoni Maurice E Disposable radioactive aerosol inhalation apparatus
US4649911A (en) 1983-09-08 1987-03-17 Baylor College Of Medicine Small particle aerosol generator for treatment of respiratory disease including the lungs
US4624251A (en) 1984-09-13 1986-11-25 Riker Laboratories, Inc. Apparatus for administering a nebulized substance
NZ241579A (en) 1991-03-25 1994-04-27 Becton Dickinson Co Antimicrobial formulations for treating the skin
US5164740A (en) 1991-04-24 1992-11-17 Yehuda Ivri High frequency printing mechanism
DK0540775T3 (da) 1991-11-07 1997-08-25 Ritzau Pari Werk Gmbh Paul Forstøver især til anvendelse i apparater til inhalationsterapi
US5934272A (en) 1993-01-29 1999-08-10 Aradigm Corporation Device and method of creating aerosolized mist of respiratory drug
US5558085A (en) 1993-01-29 1996-09-24 Aradigm Corporation Intrapulmonary delivery of peptide drugs
US5709202A (en) 1993-05-21 1998-01-20 Aradigm Corporation Intrapulmonary delivery of aerosolized formulations
WO1995009605A1 (en) 1993-10-06 1995-04-13 Henkel Corporation Improving phenolic disinfectant cleaning compositions with alkylpolyglucoside surfactants
US6034133A (en) 1993-11-05 2000-03-07 The University Of Virginia Patents Foundation Use of a virucidal hand lotion to prevent the spread of rhinovirus colds
DK0746327T3 (da) 1994-02-21 2004-05-10 Univ Aberdeen Forsuret nitrit som antimikrobielt middel
GB9804469D0 (en) 1998-03-02 1998-04-29 Univ Aberdeen Antiviral composition
US5681802A (en) 1994-06-01 1997-10-28 Lever Brothers Company, Division Of Conopco, Inc. Mild antimicrobial liquid cleansing formulations comprising buffering compound or compounds as potentiator of antimicrobial effectiveness
US5635462A (en) 1994-07-08 1997-06-03 Gojo Industries, Inc. Antimicrobial cleansing compositions
US5776430A (en) 1994-11-01 1998-07-07 Calgon Vestal, Inc. Topical antimicrobial cleanser containing chlorhexidine gluconate and alcohol
US5648101A (en) * 1994-11-14 1997-07-15 Tawashi; Rashad Drug delivery of nitric oxide
US5702754A (en) 1995-02-22 1997-12-30 Meadox Medicals, Inc. Method of providing a substrate with a hydrophilic coating and substrates, particularly medical devices, provided with such coatings
JP4484247B2 (ja) 1995-02-24 2010-06-16 エラン ファーマ インターナショナル，リミティド ナノ粒子分散体を含有するエアロゾル
ZA962455B (en) 1995-03-31 1996-10-02 B Eugene Guthery Fast acting and persistent topical antiseptic
US5758637A (en) 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
US5586550A (en) 1995-08-31 1996-12-24 Fluid Propulsion Technologies, Inc. Apparatus and methods for the delivery of therapeutic liquids to the respiratory system
US5823179A (en) 1996-02-13 1998-10-20 1263152 Ontario Inc. Nebulizer apparatus and method
US6083922A (en) 1996-04-02 2000-07-04 Pathogenesis, Corp. Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis
EP0939618B1 (en) 1996-07-10 2002-09-11 Steris Inc. Triclosan skin wash with enhanced efficacy
US5906202A (en) 1996-11-21 1999-05-25 Aradigm Corporation Device and method for directing aerosolized mist to a specific area of the respiratory tract
US6349719B2 (en) 1997-02-24 2002-02-26 Aradigm Corporation Formulation and devices for monitoring the efficacy of the delivery of aerosols
US6258368B1 (en) 1997-06-04 2001-07-10 The Procter & Gamble Company Antimicrobial wipes
US5855564A (en) 1997-08-20 1999-01-05 Aradigm Corporation Aerosol extrusion mechanism
ES2175799T3 (es) 1997-10-08 2002-11-16 Sepracor Inc Forma de dosificacion para administracion en aerosol.
DK0923957T3 (da) 1997-11-19 2002-02-18 Microflow Eng Sa Dyseemne og væskedråbesprøjteindretning til en inhalator egnet til respirationsterapi
US6192876B1 (en) 1997-12-12 2001-02-27 Astra Aktiebolag Inhalation apparatus and method
US6258371B1 (en) 1998-04-03 2001-07-10 Medtronic Inc Method for making biocompatible medical article
US6103275A (en) 1998-06-10 2000-08-15 Nitric Oxide Solutions Systems and methods for topical treatment with nitric oxide
DE69912793T2 (de) 1998-07-31 2004-09-30 First Water Ltd., Marlborough Bioadhäsive Zusammensetzungen und Biomedizinische Elektroden diese enthaltend
GB2343122B (en) 1998-10-26 2003-01-08 Medic Aid Ltd Improvements in and relating to nebulisers
US6070575A (en) 1998-11-16 2000-06-06 Aradigm Corporation Aerosol-forming porous membrane with certain pore structure
US6584971B1 (en) 1999-01-04 2003-07-01 Medic-Aid Limited Drug delivery apparatus
GB9905425D0 (en) 1999-03-09 1999-05-05 Queen Mary & Westfield College Pharmaceutical composition
JP2000355667A (ja) 1999-04-14 2000-12-26 Seiko Epson Corp カラーインクジェット記録用水系顔料インクセット、カラーインクジェット記録方法、及びカラーインクジェット記録物
US6338443B1 (en) 1999-06-18 2002-01-15 Mercury Enterprises, Inc. High efficiency medical nebulizer
US6107261A (en) 1999-06-23 2000-08-22 The Dial Corporation Compositions containing a high percent saturation concentration of antibacterial agent
EP1272243B1 (en) 2000-04-11 2005-10-26 Trudell Medical International Aerosol delivery apparatus with positive expiratory pressure capacity
GB0021317D0 (en) 2000-08-30 2000-10-18 Queen Mary & Westfield College Transdermal pharmaceutical delivery composition
GB0022084D0 (en) 2000-09-08 2000-10-25 Univ Aberdeen Treatment of multiply antibiotic-resistant organisms
US6601581B1 (en) 2000-11-01 2003-08-05 Advanced Medical Applications, Inc. Method and device for ultrasound drug delivery
GB0119011D0 (en) 2001-08-03 2001-09-26 Univ Aberdeen Treatment of nail infections
US7135189B2 (en) 2001-08-23 2006-11-14 Boston Scientific Scimed, Inc. Compositions and techniques for localized therapy
GB0125222D0 (en) 2001-10-19 2001-12-12 Barts & London Nhs Trust Composition for the treatment of microbial infections
US7066356B2 (en) 2002-08-15 2006-06-27 Ecolab Inc. Foam soap dispenser for push operation
JP4738352B2 (ja) 2004-02-09 2011-08-03 アミュレット ファーマシューティカルズ インコーポレイティッド 一酸化窒素放出ポリマー
US7838532B2 (en) 2005-05-18 2010-11-23 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
EP1917047B1 (en) 2005-07-14 2019-09-04 First Water Limited Treatment of chronic ulcerous skin lesions
CN101028229B (zh) 2006-03-02 2012-09-05 北京富丽华德生物医药科技有限公司 基于一氧化氮的新型化妆品
GB0607402D0 (en) * 2006-04-12 2006-05-24 Barts & London Nhs Trust Therapeutic composition and use
CN101062050A (zh) 2006-04-29 2007-10-31 北京尼奥克斯生物科技有限公司 一种基于一氧化氮的新型生发产品及其制备方法
RU2008152402A (ru) 2006-05-30 2010-07-10 Дзе Дайл Корпорейшн (Us) Композиции, обладающие сильным противовирусным действием
WO2008110872A2 (en) 2006-06-23 2008-09-18 Foamix Ltd. Foamable compositions and kits comprising one or more of a channel agent, a cholinergic agent, a nitric oxide donor, and related agents and their uses
GB0700911D0 (en) 2007-01-17 2007-02-28 First Water Ltd Treatment of inflammation and the complement and kinin cascades in a patient, particularly in chronic ulcerous skin lesions
GB0700908D0 (en) 2007-01-17 2007-02-28 First Water Ltd Inhibition of proteases, particularly in the treatment of chronic ulcerous skin lesions
GB0715556D0 (en) 2007-08-09 2007-09-19 Insense Ltd Improvements relating to skin dressings
US9278157B2 (en) 2007-08-09 2016-03-08 Insense Limited Nitric oxide-generating skin dressings
EP2237788A4 (en) 2007-12-27 2013-06-05 Aires Pharmaceuticals Inc COMPOUNDS FOR OBTAINING AEROSOLIZED NITRITE AND NITRIC OXIDE AND USES THEREOF
US8568793B2 (en) 2009-02-11 2013-10-29 Hope Medical Enterprises, Inc. Sodium nitrite-containing pharmaceutical compositions
US20130200109A1 (en) 2012-02-06 2013-08-08 Frank Yang Foaming soap dispensers and methods
CN103690490B (zh) 2012-08-23 2017-11-17 尼奥克斯(文莱)控股有限公司 基于微囊化化学试剂延时产生一氧化氮的系统和方法
US10517817B2 (en) 2013-05-09 2019-12-31 Syk Technologies, Llc Deep topical systemic nitric oxide therapy apparatus and method
GB201309092D0 (en) 2013-05-20 2013-07-03 Edixomed Ltd Transdermal delivery system
GB201309091D0 (en) 2013-05-20 2013-07-03 Edixomed Ltd Dressing system
US20150072023A1 (en) * 2013-09-11 2015-03-12 Advanced Inhalation Therapies (Ait) Ltd. Inhalation of nitric oxide for treating respiratory diseases
AU2015229626B2 (en) * 2014-03-14 2021-05-20 Sanotize Research And Development Corp. Treating diseases using nitric oxide releasing solutions
ES2968200T3 (es) 2016-01-27 2024-05-08 Syk Tech Llc Aparato y métodos de aplicación tópica de óxido nítrico
US11472705B2 (en) * 2018-03-13 2022-10-18 Sanotize Research And Development Corp. Nitric oxide releasing compositions
GB2599818B (en) * 2019-06-04 2024-01-31 Thirty Respiratory Ltd Methods and compositions for generating nitric oxide and uses thereof to deliver nitric oxide via the respiratory tract
EP3980373A1 (en) * 2019-06-04 2022-04-13 Thirty Holdings Limited Methods and compositions for generating nitric oxide and uses thereof
US20220273686A1 (en) * 2019-08-06 2022-09-01 Lianyungang Jinkang Hexin Pharmaceutical Co., Ltd. Pharmaceutical composition for producing safe amount of nitric oxide and use thereof
JP2023526583A (ja) * 2020-04-23 2023-06-22 サーティー レスピラトリー リミテッド 結核を治療及び抑制するための方法及び組成物

Also Published As

Publication number Publication date
GB2610722A (en) 2023-03-15
WO2021214440A1 (en) 2021-10-28
EP4138795A1 (en) 2023-03-01
JP2023526584A (ja) 2023-06-22
GB202217440D0 (en) 2023-01-04
CN115884758A (zh) 2023-03-31
BR112022021454A2 (pt) 2023-01-31
US20240016831A1 (en) 2024-01-18
AU2021259360A1 (en) 2022-12-01
GB2610722B (en) 2024-07-31

Similar Documents

Publication Publication Date Title
AU2020286987B2 (en) Methods and compositions for generating nitric oxide and uses thereof to deliver nitric oxide via the respiratory tract
AU2020286677B2 (en) Methods and compositions for generating nitric oxide and uses thereof
US20240016831A1 (en) Nitric oxide or nitric oxide releasing compositions for use in treating sars-cov and sars-cov-2
US20230172973A1 (en) Methods and compositions for treating and combatting tuberculosis
AU2002334190B2 (en) Therapeutic composition and use
AU2002334190A1 (en) Therapeutic composition and use
JP2023513106A (ja) 一酸化窒素放出抗菌化合物、製剤、およびそれらに関連する方法
CN102427811A (zh) 适于局部治疗皮肤和指(趾)甲真菌感染的组合物
JP2025143385A (ja) クロファジミンの組成物、それを含む組合せ、その調製プロセス、それを含む使用及び処置方法
CN108472377A (zh) 抗真菌剂
US20210252048A1 (en) Treatment of lung and airway diseases and disorders
CN116568138A (zh) 用于消毒、治疗和预防微生物感染的组合物和方法
JP2025503797A (ja) 非結核性抗酸菌疾患を治療する方法
GB2644374A (en) Compositions and kits for generating nitric oxide
WO2022235781A1 (en) Treatment of lung and airway diseases and disorders

Legal Events

Date Code Title Description
MFA Maintenance fee for application paid

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 4TH ANNIV.) - STANDARD

Year of fee payment: 4

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250415

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250415

D11 Substantive examination requested

Free format text: ST27 STATUS EVENT CODE: A-1-1-D10-D11-D117 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: REQUEST FOR EXAMINATION RECEIVED

Effective date: 20250416

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W200 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: REQUEST OR RESPONSE SUBMITTED ONLINE

Effective date: 20250416

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT

Effective date: 20250416

D00 Search and/or examination requested or commenced

Free format text: ST27 STATUS EVENT CODE: A-1-1-D10-D00-D118 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: REQUEST FOR EXAMINATION REQUIREMENTS DETERMINED COMPLIANT

Effective date: 20250604

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20250604

D11 Substantive examination requested

Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D11-D155 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: ALL REQUIREMENTS FOR EXAMINATION DETERMINED COMPLIANT

Effective date: 20250605

MFA Maintenance fee for application paid

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 5TH ANNIV.) - STANDARD

Year of fee payment: 5

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20260304

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20260304

D15 Examination report completed

Free format text: ST27 STATUS EVENT CODE: A-2-2-D10-D15-D126 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: EXAMINER'S REPORT

Effective date: 20260317