CA3179579A1 - Pathogen diagnostic test - Google Patents

Pathogen diagnostic test

Info

Publication number
CA3179579A1
CA3179579A1 CA3179579A CA3179579A CA3179579A1 CA 3179579 A1 CA3179579 A1 CA 3179579A1 CA 3179579 A CA3179579 A CA 3179579A CA 3179579 A CA3179579 A CA 3179579A CA 3179579 A1 CA3179579 A1 CA 3179579A1
Authority
CA
Canada
Prior art keywords
nucleic acid
sequence
coronavirus
seq
synthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3179579A
Other languages
English (en)
French (fr)
Inventor
Sriram Kosuri
Eric Matthew JONES
Aaron Cooper
Molly Jeanette GASPERINI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Octant Inc
Original Assignee
Octant Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octant Inc filed Critical Octant Inc
Publication of CA3179579A1 publication Critical patent/CA3179579A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
    • C12Q2535/122—Massive parallel sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA3179579A 2020-04-06 2021-04-05 Pathogen diagnostic test Pending CA3179579A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202063005996P 2020-04-06 2020-04-06
US63/005,996 2020-04-06
US202063062406P 2020-08-06 2020-08-06
US63/062,406 2020-08-06
US202163136449P 2021-01-12 2021-01-12
US63/136,449 2021-01-12
US202163154571P 2021-02-26 2021-02-26
US63/154,571 2021-02-26
PCT/US2021/025806 WO2021207091A1 (en) 2020-04-06 2021-04-05 Pathogen diagnostic test

Publications (1)

Publication Number Publication Date
CA3179579A1 true CA3179579A1 (en) 2021-10-14

Family

ID=75675001

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3179579A Pending CA3179579A1 (en) 2020-04-06 2021-04-05 Pathogen diagnostic test

Country Status (11)

Country Link
US (2) US12129523B2 (https=)
EP (2) EP4286538A3 (https=)
JP (1) JP7801240B2 (https=)
KR (1) KR20220164745A (https=)
CN (1) CN115917002A (https=)
AU (1) AU2021251703A1 (https=)
BR (1) BR112022020143A2 (https=)
CA (1) CA3179579A1 (https=)
IL (1) IL297033A (https=)
MX (1) MX2022012516A (https=)
WO (1) WO2021207091A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230019965A (ko) * 2020-06-22 2023-02-09 주식회사 씨젠 검체 내 타겟 핵산 서열 검출을 위한 준비물을 제공하는 방법
CA3240812A1 (en) * 2021-12-22 2023-06-29 Carter BARGER Quality control for reporter screening assays
US12553093B1 (en) * 2025-03-26 2026-02-17 Wolf of Zion, Inc. Methods of detecting, identifying and quantifying wild spike protein and covid vaccine spike proteins

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7582740B2 (en) * 2003-04-17 2009-09-01 The Trustees Of Columbia University In The City Of New York Methods and kits for detecting SARS-associated coronavirus
EP1957678B1 (en) 2005-11-28 2012-06-13 Ibis Biosciences, Inc. Compositions for use in identification of adventitious contaminant viruses
CN101384730A (zh) * 2005-12-23 2009-03-11 阿尔维德医药技术公司 用于传染病和癌症检测的分子信标成像的方法和应用
US8354230B2 (en) * 2007-12-21 2013-01-15 Quest Diagnostics Investments Inc. Multiplex detection assay for influenza and RSV viruses
EP2913402B1 (en) * 2010-07-16 2017-10-18 Tocagen Inc. Retrovirus detection
WO2013006793A2 (en) 2011-07-06 2013-01-10 Quest Diagnostics Investments Incorporated Direct amplification and detection of viral and bacterial pathogens
WO2016057749A1 (en) * 2014-10-08 2016-04-14 Theranos, Inc. Methods and devices for real-time diagnostic testing (rdt) for ebola and other infectious diseases
JP6873921B2 (ja) * 2015-05-18 2021-05-19 カリウス・インコーポレイテッド 核酸の集団を濃縮するための組成物および方法
JP2017209036A (ja) * 2016-05-24 2017-11-30 東洋紡株式会社 改良されたウイルス検出方法
JP7167913B2 (ja) 2017-04-26 2022-11-09 東洋紡株式会社 ウイルスの検査方法およびウイルスの検査用キット
JP7796660B2 (ja) * 2020-03-09 2026-01-09 エフ． ホフマン－ラ ロシュ アーゲー 重症急性呼吸器症候群コロナウイルス２（ｓａｒｓ－ｃｏｖ－２）、インフルエンザａ及びインフルエンザｂを検出するための組成物及び方法
CN111494616A (zh) * 2020-04-27 2020-08-07 重庆医科大学附属永川医院 一种新冠病毒免疫增强型基因疫苗及其制备方法

Also Published As

Publication number Publication date
WO2021207091A1 (en) 2021-10-14
MX2022012516A (es) 2023-01-19
JP2023520590A (ja) 2023-05-17
JP7801240B2 (ja) 2026-01-16
CN115917002A (zh) 2023-04-04
BR112022020143A2 (pt) 2023-02-28
EP4286538A3 (en) 2024-03-20
US12129523B2 (en) 2024-10-29
AU2021251703A1 (en) 2022-11-10
EP4286538A2 (en) 2023-12-06
US20220356535A1 (en) 2022-11-10
IL297033A (en) 2022-12-01
EP4133103A1 (en) 2023-02-15
US20250084492A1 (en) 2025-03-13
KR20220164745A (ko) 2022-12-13

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