CA3179048A1 - Use of bupropion and dextromethorphan combinations for treating neurological disorders - Google Patents

Use of bupropion and dextromethorphan combinations for treating neurological disorders

Info

Publication number
CA3179048A1
CA3179048A1 CA3179048A CA3179048A CA3179048A1 CA 3179048 A1 CA3179048 A1 CA 3179048A1 CA 3179048 A CA3179048 A CA 3179048A CA 3179048 A CA3179048 A CA 3179048A CA 3179048 A1 CA3179048 A1 CA 3179048A1
Authority
CA
Canada
Prior art keywords
nnl
dextronnethorphan
bupropion
human
week
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3179048A
Other languages
English (en)
French (fr)
Inventor
Herriot TABUTEAU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antecip Bioventures II LLC
Original Assignee
Antecip Bioventures II LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/894,713 external-priority patent/US10898453B2/en
Application filed by Antecip Bioventures II LLC filed Critical Antecip Bioventures II LLC
Publication of CA3179048A1 publication Critical patent/CA3179048A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA3179048A 2020-03-30 2021-03-29 Use of bupropion and dextromethorphan combinations for treating neurological disorders Pending CA3179048A1 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US202063002132P 2020-03-30 2020-03-30
US63/002,132 2020-03-30
US202063016178P 2020-04-27 2020-04-27
US63/016,178 2020-04-27
US202063032517P 2020-05-29 2020-05-29
US63/032,517 2020-05-29
US202063032567P 2020-05-30 2020-05-30
US63/032,567 2020-05-30
US16/894,713 2020-06-05
US16/894,713 US10898453B2 (en) 2013-11-05 2020-06-05 Bupropion as a modulator of drug activity
PCT/US2021/024718 WO2021202419A1 (en) 2020-03-30 2021-03-29 Use of bupropion and dextromethorphan combinations for treating neurological disorders

Publications (1)

Publication Number Publication Date
CA3179048A1 true CA3179048A1 (en) 2021-10-07

Family

ID=77930161

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3179048A Pending CA3179048A1 (en) 2020-03-30 2021-03-29 Use of bupropion and dextromethorphan combinations for treating neurological disorders

Country Status (6)

Country Link
EP (1) EP4125837A4 (ko)
JP (1) JP2023519965A (ko)
KR (1) KR20220161414A (ko)
CN (1) CN115697314A (ko)
CA (1) CA3179048A1 (ko)
WO (1) WO2021202419A1 (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12109178B2 (en) 2013-11-05 2024-10-08 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11969421B2 (en) 2013-11-05 2024-04-30 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11433067B2 (en) 2013-11-05 2022-09-06 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
WO2022119981A1 (en) 2020-12-01 2022-06-09 Antecip Bioventures Ii Llc Bupropion and dextromethrophan for reduction of suicide risk in depression patients
CA3227072A1 (en) * 2021-07-21 2023-01-26 Antecip Bioventures Ii Llc Treatment of depression
WO2023225511A1 (en) * 2022-05-17 2023-11-23 Antecip Bioventures Ii Llc Treatment of depression
US11717518B1 (en) 2022-06-30 2023-08-08 Antecip Bioventures Ii Llc Bupropion dosage forms with reduced food and alcohol dosing effects
US12036191B1 (en) 2022-06-30 2024-07-16 Antecip Bioventures Ii Llc Treatment of poor metabolizers of dextromethorphan with a combination of bupropion and dextromethorphan
US11730706B1 (en) 2022-07-07 2023-08-22 Antecip Bioventures Ii Llc Treatment of depression in certain patient populations
US11844797B1 (en) 2023-04-20 2023-12-19 Antecip Bioventures Ii Llc Combination of dextromethorphan and bupropion for treating depression
WO2024118570A1 (en) * 2022-11-28 2024-06-06 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10898453B2 (en) * 2013-11-05 2021-01-26 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11007189B2 (en) * 2013-11-05 2021-05-18 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11234946B2 (en) * 2013-11-05 2022-02-01 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US11273134B2 (en) * 2013-11-05 2022-03-15 Antecip Bioventures Ii Llc Bupropion as a modulator of drug activity
US9763932B2 (en) * 2013-11-05 2017-09-19 Antecip Bioventures Ii Llc Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic effects
SG10201911816XA (en) * 2013-11-05 2020-01-30 Antecip Bioventures Ii Llc Compositions and methods comprising bupropion or related compounds and dextromethorphan
US10080727B2 (en) * 2013-11-05 2018-09-25 Antecip Bioventures Ii Llc Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic effects

Also Published As

Publication number Publication date
EP4125837A1 (en) 2023-02-08
CN115697314A (zh) 2023-02-03
JP2023519965A (ja) 2023-05-15
KR20220161414A (ko) 2022-12-06
EP4125837A4 (en) 2024-03-20
WO2021202419A1 (en) 2021-10-07

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