CA3178173A1 - Procede et dispositif de determination de la concentration d'analyte dans le sang total - Google Patents
Procede et dispositif de determination de la concentration d'analyte dans le sang totalInfo
- Publication number
- CA3178173A1 CA3178173A1 CA3178173A CA3178173A CA3178173A1 CA 3178173 A1 CA3178173 A1 CA 3178173A1 CA 3178173 A CA3178173 A CA 3178173A CA 3178173 A CA3178173 A CA 3178173A CA 3178173 A1 CA3178173 A1 CA 3178173A1
- Authority
- CA
- Canada
- Prior art keywords
- channel
- whole blood
- light
- concentration
- analyte
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004369 blood Anatomy 0.000 title claims abstract description 41
- 239000008280 blood Substances 0.000 title claims abstract description 41
- 239000012491 analyte Substances 0.000 title claims abstract description 28
- 238000000034 method Methods 0.000 title abstract description 22
- 239000013307 optical fiber Substances 0.000 claims description 16
- 210000000601 blood cell Anatomy 0.000 claims description 6
- 210000002381 plasma Anatomy 0.000 description 35
- 210000003743 erythrocyte Anatomy 0.000 description 11
- 239000011521 glass Substances 0.000 description 11
- 206010018910 Haemolysis Diseases 0.000 description 10
- 230000008588 hemolysis Effects 0.000 description 10
- 230000000694 effects Effects 0.000 description 8
- 239000012780 transparent material Substances 0.000 description 6
- 102000001554 Hemoglobins Human genes 0.000 description 3
- 108010054147 Hemoglobins Proteins 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000005253 cladding Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011143 downstream manufacturing Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- -1 for example Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 230000008105 immune reaction Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 208000007056 sickle cell anemia Diseases 0.000 description 1
- 239000013306 transparent fiber Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
- G01N21/552—Attenuated total reflection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
- G01N2021/052—Tubular type; cavity type; multireflective
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Ecology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762520087P | 2017-06-15 | 2017-06-15 | |
US62/520,087 | 2017-06-15 | ||
CA3067020A CA3067020C (fr) | 2017-06-15 | 2018-06-07 | Procede et dispositif de determination de la concentration d'analyte dans le sang total |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3067020A Division CA3067020C (fr) | 2017-06-15 | 2018-06-07 | Procede et dispositif de determination de la concentration d'analyte dans le sang total |
Publications (1)
Publication Number | Publication Date |
---|---|
CA3178173A1 true CA3178173A1 (fr) | 2018-12-20 |
Family
ID=64660669
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3067020A Active CA3067020C (fr) | 2017-06-15 | 2018-06-07 | Procede et dispositif de determination de la concentration d'analyte dans le sang total |
CA3178173A Pending CA3178173A1 (fr) | 2017-06-15 | 2018-06-07 | Procede et dispositif de determination de la concentration d'analyte dans le sang total |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3067020A Active CA3067020C (fr) | 2017-06-15 | 2018-06-07 | Procede et dispositif de determination de la concentration d'analyte dans le sang total |
Country Status (8)
Country | Link |
---|---|
US (1) | US11480558B2 (fr) |
EP (2) | EP4134657A1 (fr) |
JP (2) | JP6942207B2 (fr) |
CA (2) | CA3067020C (fr) |
DK (1) | DK3638109T3 (fr) |
IL (1) | IL271254B2 (fr) |
MX (1) | MX2019015114A (fr) |
WO (1) | WO2018231625A1 (fr) |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9401102D0 (sv) * | 1994-03-31 | 1994-03-31 | Pharmacia Biosensor Ab | Assay method |
US6174424B1 (en) * | 1995-11-20 | 2001-01-16 | Cirrex Corp. | Couplers for optical fibers |
US5650846A (en) | 1995-11-21 | 1997-07-22 | Hewlett-Packard Company | Microcolumnar analytical system with optical fiber sensor |
WO1998038961A1 (fr) * | 1997-03-03 | 1998-09-11 | Cme Telemetrix Inc. | Methode et dispositif pour analyser le plasma a la recherche de substances perturbatrices contenues dans le plasma provenant de poches de sang de donneurs |
NZ523939A (en) * | 2000-07-21 | 2003-05-30 | Vir As | Holographic interference developed diffraction grating coupling elements for surface plasmon resonance sensors |
US7887750B2 (en) | 2004-05-05 | 2011-02-15 | Bayer Healthcare Llc | Analytical systems, devices, and cartridges therefor |
US20060204403A1 (en) * | 2005-02-28 | 2006-09-14 | Careside Medical, Llc | Micro-fluidic fluid separation device and method |
US20080240543A1 (en) * | 2007-03-30 | 2008-10-02 | Wolfgang Ernst Gustav Budach | Calibration and normalization method for biosensors |
DE102011085394B4 (de) * | 2011-10-28 | 2015-04-02 | INSTITUT FüR MIKROTECHNIK MAINZ GMBH | Vorrichtung zur Analyse eines Fluids mittels Evaneszenzfeldspektroskopie und Dielektrophorese |
JP5901012B2 (ja) * | 2012-02-13 | 2016-04-06 | 国立大学法人 東京医科歯科大学 | 血液情報の測定方法及び装置 |
AU2014241111B2 (en) | 2013-03-14 | 2017-03-02 | Instrumentation Laboratory Company | Whole blood hemolysis sensor |
DE102015007029A1 (de) * | 2015-06-02 | 2016-12-08 | Fachhochschule Lübeck | Fluidprobenvorrichtung und deren Herstellung, Fluidanalysevorrichtung und optisches Messverfahren |
US10288600B2 (en) * | 2016-05-20 | 2019-05-14 | Instrumentation Laboratory Company | Evanescent hemolysis detection |
-
2018
- 2018-06-07 EP EP22193163.7A patent/EP4134657A1/fr active Pending
- 2018-06-07 JP JP2019569461A patent/JP6942207B2/ja active Active
- 2018-06-07 CA CA3067020A patent/CA3067020C/fr active Active
- 2018-06-07 DK DK18817299.3T patent/DK3638109T3/da active
- 2018-06-07 MX MX2019015114A patent/MX2019015114A/es unknown
- 2018-06-07 US US16/621,009 patent/US11480558B2/en active Active
- 2018-06-07 CA CA3178173A patent/CA3178173A1/fr active Pending
- 2018-06-07 WO PCT/US2018/036434 patent/WO2018231625A1/fr unknown
- 2018-06-07 EP EP18817299.3A patent/EP3638109B1/fr active Active
-
2019
- 2019-12-08 IL IL271254A patent/IL271254B2/en unknown
-
2021
- 2021-09-06 JP JP2021144966A patent/JP7170804B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
JP7170804B2 (ja) | 2022-11-14 |
CA3067020C (fr) | 2023-10-03 |
JP2022020613A (ja) | 2022-02-01 |
JP2020523602A (ja) | 2020-08-06 |
US11480558B2 (en) | 2022-10-25 |
EP4134657A1 (fr) | 2023-02-15 |
IL271254A (en) | 2020-01-30 |
MX2019015114A (es) | 2020-08-03 |
EP3638109A1 (fr) | 2020-04-22 |
JP6942207B2 (ja) | 2021-09-29 |
EP3638109B1 (fr) | 2022-10-26 |
US20200200730A1 (en) | 2020-06-25 |
WO2018231625A1 (fr) | 2018-12-20 |
EP3638109A4 (fr) | 2020-06-17 |
DK3638109T3 (da) | 2023-01-23 |
CA3067020A1 (fr) | 2018-12-20 |
IL271254B2 (en) | 2023-05-01 |
IL271254B1 (en) | 2023-01-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request |
Effective date: 20220930 |
|
EEER | Examination request |
Effective date: 20220930 |
|
EEER | Examination request |
Effective date: 20220930 |
|
EEER | Examination request |
Effective date: 20220930 |
|
EEER | Examination request |
Effective date: 20220930 |
|
EEER | Examination request |
Effective date: 20220930 |