CA3172143A1 - Detecting pancreatic neuroendocrine tumors - Google Patents
Detecting pancreatic neuroendocrine tumors Download PDFInfo
- Publication number
- CA3172143A1 CA3172143A1 CA3172143A CA3172143A CA3172143A1 CA 3172143 A1 CA3172143 A1 CA 3172143A1 CA 3172143 A CA3172143 A CA 3172143A CA 3172143 A CA3172143 A CA 3172143A CA 3172143 A1 CA3172143 A1 CA 3172143A1
- Authority
- CA
- Canada
- Prior art keywords
- methylation
- sample
- dna
- bisulfite
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2523/00—Reactions characterised by treatment of reaction samples
- C12Q2523/10—Characterised by chemical treatment
- C12Q2523/125—Bisulfite(s)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/164—Methylation detection other then bisulfite or methylation sensitive restriction endonucleases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063019751P | 2020-05-04 | 2020-05-04 | |
| US63/019,751 | 2020-05-04 | ||
| PCT/US2021/030635 WO2021226071A2 (en) | 2020-05-04 | 2021-05-04 | Detecting pancreatic neuroendocrine tumors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3172143A1 true CA3172143A1 (en) | 2021-11-11 |
Family
ID=78468349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3172143A Pending CA3172143A1 (en) | 2020-05-04 | 2021-05-04 | Detecting pancreatic neuroendocrine tumors |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230167506A1 (enExample) |
| EP (1) | EP4146678A4 (enExample) |
| JP (2) | JP7830350B2 (enExample) |
| KR (1) | KR20230005845A (enExample) |
| CN (1) | CN115551880A (enExample) |
| AU (1) | AU2021268631A1 (enExample) |
| CA (1) | CA3172143A1 (enExample) |
| WO (1) | WO2021226071A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8673555B2 (en) | 2008-02-15 | 2014-03-18 | Mayo Foundation For Medical Education And Research | Detecting neoplasm |
| US8361720B2 (en) | 2010-11-15 | 2013-01-29 | Exact Sciences Corporation | Real time cleavage assay |
| EP2971179B1 (en) | 2013-03-14 | 2019-01-09 | Mayo Foundation for Medical Education and Research | Detecting neoplasm |
| US10301680B2 (en) | 2014-03-31 | 2019-05-28 | Mayo Foundation For Medical Education And Research | Detecting colorectal neoplasm |
| US10184154B2 (en) | 2014-09-26 | 2019-01-22 | Mayo Foundation For Medical Education And Research | Detecting cholangiocarcinoma |
| WO2016160454A1 (en) | 2015-03-27 | 2016-10-06 | Exact Sciences Corporation | Detecting esophageal disorders |
| JP6871926B2 (ja) | 2015-08-31 | 2021-05-19 | マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチＭａｙｏ Ｆｏｕｎｄａｔｉｏｎ ｆｏｒ Ｍｅｄｉｃａｌ Ｅｄｕｃａｔｉｏｎ ａｎｄ Ｒｅｓｅａｒｃｈ | 胃の新生物を検出すること |
| CA3002196C (en) | 2015-10-30 | 2024-05-14 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay and isolation and detection of dna from plasma |
| AU2017260630B2 (en) | 2016-05-05 | 2023-07-13 | Exact Sciences Corporation | Detection of lung neoplasia by analysis of methylated DNA |
| AU2018211956B2 (en) | 2017-01-27 | 2024-06-20 | Exact Sciences Corporation | Detection of colon neoplasia by analysis of methylated DNA |
| AU2018374176B2 (en) | 2017-11-30 | 2024-12-12 | Exact Sciences Corporation | Detecting breast cancer |
| US10648025B2 (en) | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
| CA3127329A1 (en) | 2019-01-24 | 2020-07-30 | Mayo Foundation For Medical Education And Research | Detecting endometrial cancer |
| JP7799607B2 (ja) | 2019-10-31 | 2026-01-15 | マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチ | 卵巣癌の検出 |
| US20250333782A1 (en) * | 2022-03-31 | 2025-10-30 | Illumina, Inc. | Compositions including aqueous amine borane complexes and polynucleotides, and methods of using the same to detect methylcytosine or hydroxymethylcytosine |
| WO2025194302A1 (zh) * | 2024-03-18 | 2025-09-25 | 深圳华大基因股份有限公司 | 差异化甲基化区域组合及应用 |
| WO2026024692A1 (en) * | 2024-07-24 | 2026-01-29 | Guardant Health, Inc. | Direct methylation single-base resolution sequencing of enriched unmethylated dna |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090077685A1 (en) * | 1998-06-16 | 2009-03-19 | Buehler Robert E | Nucleic acid molecules and other molecules associated with plants |
| WO2002018631A2 (de) | 2000-09-01 | 2002-03-07 | Epigenomics Ag | Diagnose von bestehenden erkrankungen oder der prädisposition für bestimmte erkrankungen |
| CA2519456A1 (en) * | 2003-03-17 | 2004-09-30 | Michael G. Goggins | Aberrantly methylated genes in pancreatic cancer |
| EP2097538A4 (en) * | 2006-12-07 | 2011-11-30 | Switchgear Genomics | TRANSCRIPTION REAGULATION ELEMENTS OF BIOLOGICAL PATHS, TOOLS AND METHODS |
| WO2012175562A2 (en) * | 2011-06-21 | 2012-12-27 | University Of Tartu | Methylation and microrna markers of early-stage non-small cell lung cancer |
| US10106854B2 (en) * | 2012-06-14 | 2018-10-23 | Aarhus Universitet | Biomarkers for prostate cancer |
| US20140349856A1 (en) * | 2013-03-15 | 2014-11-27 | Biotheranostics, Inc. | Neuroendocrine Tumors |
| EP3189156B1 (en) * | 2014-08-08 | 2020-10-07 | AIT Austrian Institute of Technology GmbH | Thyroid cancer diagnosis by dna methylation analysis |
| CN109153993B (zh) | 2016-04-14 | 2023-02-17 | 梅约医学教育与研究基金会 | 检测胰腺高度异型增生 |
| US10370726B2 (en) * | 2016-04-14 | 2019-08-06 | Mayo Foundation For Medical Education And Research | Detecting colorectal neoplasia |
| US10934592B2 (en) | 2017-02-28 | 2021-03-02 | Mayo Foundation For Medical Education And Research | Detecting prostate cancer |
| WO2019010429A1 (en) * | 2017-07-07 | 2019-01-10 | The Trustees Of The University Of Pennsylvania | METHODS OF DIAGNOSING PANCREATIC CANCER |
| US10648025B2 (en) * | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
-
2021
- 2021-05-04 CA CA3172143A patent/CA3172143A1/en active Pending
- 2021-05-04 US US17/921,710 patent/US20230167506A1/en active Pending
- 2021-05-04 EP EP21800508.0A patent/EP4146678A4/en active Pending
- 2021-05-04 AU AU2021268631A patent/AU2021268631A1/en active Pending
- 2021-05-04 CN CN202180028122.XA patent/CN115551880A/zh active Pending
- 2021-05-04 WO PCT/US2021/030635 patent/WO2021226071A2/en not_active Ceased
- 2021-05-04 JP JP2022567116A patent/JP7830350B2/ja active Active
- 2021-05-04 KR KR1020227037904A patent/KR20230005845A/ko active Pending
-
2026
- 2026-03-04 JP JP2026034032A patent/JP2026094340A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4146678A2 (en) | 2023-03-15 |
| JP2026094340A (ja) | 2026-06-09 |
| WO2021226071A2 (en) | 2021-11-11 |
| CN115551880A (zh) | 2022-12-30 |
| JP7830350B2 (ja) | 2026-03-16 |
| US20230167506A1 (en) | 2023-06-01 |
| WO2021226071A3 (en) | 2021-12-09 |
| KR20230005845A (ko) | 2023-01-10 |
| AU2021268631A1 (en) | 2023-01-05 |
| JP2023524740A (ja) | 2023-06-13 |
| EP4146678A4 (en) | 2025-08-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US12601011B2 (en) | Detecting gastric neoplasm | |
| JP7830350B2 (ja) | 膵神経内分泌腫瘍の検出 | |
| JP7799607B2 (ja) | 卵巣癌の検出 | |
| AU2020254760B2 (en) | Detecting pancreatic ductal adenocarcinoma in plasma | |
| US20230357852A1 (en) | Detecting non-hodgkin lymphoma | |
| JP2024133634A (ja) | 子宮内膜癌の検出 | |
| EP4146677A2 (en) | Detecting melanoma | |
| EP3589732A1 (en) | Detecting prostate cancer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20220916 |
|
| D15 | Examination report completed |
Free format text: ST27 STATUS EVENT CODE: A-2-2-D10-D15-D126 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: EXAMINER'S REPORT Effective date: 20250402 |
|
| MFA | Maintenance fee for application paid |
Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 4TH ANNIV.) - STANDARD Year of fee payment: 4 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250425 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250425 |
|
| P11 | Amendment of application requested |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT RECEIVED - RESPONSE TO EXAMINER'S REQUISITION Effective date: 20250725 |
|
| P11 | Amendment of application requested |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-P102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: AMENDMENT DETERMINED COMPLIANT Effective date: 20250730 |
|
| P13 | Application amended |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P13-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: APPLICATION AMENDED Effective date: 20250730 |
|
| W00 | Other event occurred |
Free format text: ST27 STATUS EVENT CODE: A-2-2-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT Effective date: 20250730 |