CA3170531A1 - Proximity assay - Google Patents

Proximity assay

Info

Publication number
CA3170531A1
CA3170531A1 CA3170531A CA3170531A CA3170531A1 CA 3170531 A1 CA3170531 A1 CA 3170531A1 CA 3170531 A CA3170531 A CA 3170531A CA 3170531 A CA3170531 A CA 3170531A CA 3170531 A1 CA3170531 A1 CA 3170531A1
Authority
CA
Canada
Prior art keywords
analyte
signal
host cells
complex
population
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3170531A
Other languages
English (en)
French (fr)
Inventor
Jia Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Absci Corp
Original Assignee
Absci Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2021/013734 external-priority patent/WO2021146626A1/en
Application filed by Absci Corp filed Critical Absci Corp
Publication of CA3170531A1 publication Critical patent/CA3170531A1/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Valve Device For Special Equipments (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA3170531A 2020-02-11 2021-02-11 Proximity assay Pending CA3170531A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062975152P 2020-02-11 2020-02-11
US62/975,152 2020-02-11
USPCT/US2021/013734 2021-01-15
PCT/US2021/013734 WO2021146626A1 (en) 2020-01-15 2021-01-15 Activity-specific cell enrichment
PCT/US2021/017688 WO2021163349A1 (en) 2020-02-11 2021-02-11 Proximity assay

Publications (1)

Publication Number Publication Date
CA3170531A1 true CA3170531A1 (en) 2021-08-19

Family

ID=77292601

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3170531A Pending CA3170531A1 (en) 2020-02-11 2021-02-11 Proximity assay

Country Status (8)

Country Link
EP (1) EP4103742A4 (es)
JP (1) JP2023513578A (es)
CN (1) CN115362263A (es)
AU (1) AU2021218706A1 (es)
CA (1) CA3170531A1 (es)
IL (1) IL295335A (es)
MX (1) MX2022009783A (es)
WO (1) WO2021163349A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023122567A1 (en) 2021-12-21 2023-06-29 Absci Corporation Fola selection assay to identify strains with increased soluble target protein expression
CA3240314A1 (en) 2021-12-23 2023-06-29 Absci Corporation Products and methods for heterologous expression of proteins in a host cell
WO2023129881A1 (en) 2021-12-30 2023-07-06 Absci Corporation Knockout of ptsp gene elevates active gene expression
US20230268026A1 (en) 2022-01-07 2023-08-24 Absci Corporation Designing biomolecule sequence variants with pre-specified attributes

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003067210A2 (en) * 2001-07-10 2003-08-14 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for detecting the activation state of the multiple proteins in single cells
US20080108128A1 (en) * 2003-11-19 2008-05-08 Eidne Karin A Resonance Energy Transfer Assay System for Multi-Component Detection
BRPI0717416A2 (pt) * 2006-09-21 2013-11-12 Prometheus Lab Inc Método para realizar um imunoensaio complexo de alta produtividade, e, arranjo
WO2016000966A1 (en) * 2014-06-30 2016-01-07 Nestec S.A. Collaborative enzyme enhanced reactive (ceer) immunoassay using flow cytometry

Also Published As

Publication number Publication date
EP4103742A4 (en) 2024-06-05
MX2022009783A (es) 2022-11-09
JP2023513578A (ja) 2023-03-31
WO2021163349A1 (en) 2021-08-19
CN115362263A (zh) 2022-11-18
AU2021218706A1 (en) 2022-09-22
IL295335A (en) 2022-10-01
EP4103742A1 (en) 2022-12-21

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