CA3164914A1 - Dosing regimens and methods for treating cancer - Google Patents

Dosing regimens and methods for treating cancer Download PDF

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Publication number
CA3164914A1
CA3164914A1 CA3164914A CA3164914A CA3164914A1 CA 3164914 A1 CA3164914 A1 CA 3164914A1 CA 3164914 A CA3164914 A CA 3164914A CA 3164914 A CA3164914 A CA 3164914A CA 3164914 A1 CA3164914 A1 CA 3164914A1
Authority
CA
Canada
Prior art keywords
2dehspm
cancer
treatment
patient
days
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3164914A
Other languages
English (en)
French (fr)
Inventor
Suzanne Gagnon
Thomas X. Neenan
Michael T. CULLEN
Michael Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Panbela Therapeutics Inc
Original Assignee
Panbela Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panbela Therapeutics Inc filed Critical Panbela Therapeutics Inc
Publication of CA3164914A1 publication Critical patent/CA3164914A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/131Amines acyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/133Amines having hydroxy groups, e.g. sphingosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA3164914A 2020-01-20 2021-01-20 Dosing regimens and methods for treating cancer Pending CA3164914A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062963492P 2020-01-20 2020-01-20
US62/963,492 2020-01-20
PCT/US2021/014112 WO2021150559A1 (en) 2020-01-20 2021-01-20 Dosing regimens and methods for treating cancer

Publications (1)

Publication Number Publication Date
CA3164914A1 true CA3164914A1 (en) 2021-07-29

Family

ID=76992702

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3164914A Pending CA3164914A1 (en) 2020-01-20 2021-01-20 Dosing regimens and methods for treating cancer

Country Status (6)

Country Link
US (1) US20230064990A1 (https=)
EP (1) EP4093386A4 (https=)
JP (1) JP2023512487A (https=)
AU (1) AU2021210867A1 (https=)
CA (1) CA3164914A1 (https=)
WO (1) WO2021150559A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2026501282A (ja) * 2022-12-20 2026-01-14 ジェネンテック, インコーポレイテッド Pd-1軸結合アンタゴニストおよびrnaワクチンを用いて膵臓がんを処置する方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6160022A (en) * 1999-07-19 2000-12-12 University Of Florida Chemical resection of pancreas
US20130137772A1 (en) * 2011-11-29 2013-05-30 Raymond J. Bergeron Hydroxypolyamine salts
WO2017062704A1 (en) * 2015-10-08 2017-04-13 Sun Biopharma, Inc. Compositions and methods for treating pancreatitis
US10195188B2 (en) * 2016-06-13 2019-02-05 Chemocentryx, Inc. Method of treating pancreatic cancer
EP4257581A1 (en) * 2018-01-30 2023-10-11 Panbela Therapeutics, Inc. Methods for producing (6s,15s)-3,8,13,18-tetraazaicosane-6,15-diol

Also Published As

Publication number Publication date
EP4093386A1 (en) 2022-11-30
EP4093386A4 (en) 2024-01-10
AU2021210867A1 (en) 2022-08-18
WO2021150559A1 (en) 2021-07-29
US20230064990A1 (en) 2023-03-02
JP2023512487A (ja) 2023-03-27

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