CA3106105A1 - Methodes de diagnostic et de traitement d'implants infectes - Google Patents

Methodes de diagnostic et de traitement d'implants infectes Download PDF

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Publication number
CA3106105A1
CA3106105A1 CA3106105A CA3106105A CA3106105A1 CA 3106105 A1 CA3106105 A1 CA 3106105A1 CA 3106105 A CA3106105 A CA 3106105A CA 3106105 A CA3106105 A CA 3106105A CA 3106105 A1 CA3106105 A1 CA 3106105A1
Authority
CA
Canada
Prior art keywords
biofilm
pca
implant
composition
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3106105A
Other languages
English (en)
Inventor
Lanny Leo Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/058,909 external-priority patent/US10398664B2/en
Application filed by Individual filed Critical Individual
Publication of CA3106105A1 publication Critical patent/CA3106105A1/fr
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/11—Aldehydes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne l'acide protocatéchuique, le 2,4,6-trihydroxybenzaldéhyde ou un mélange ou une combinaison associés, destinés à être utilisés dans une méthode de traitement d'infections microbiennes sur les surfaces d'un implant ou d'autres surfaces à proximité d'un implant chez un patient. En particulier, les méthodes sont utiles pour traiter des infections par biofilm. Les méthodes comprennent l'utilisation de techniques minimalement invasives, notamment l'utilisation d'ultrasons en vue de faciliter la détection d'infections par biofilm sur l'implant ou une autre surface chez un patient et d'éliminer l'infection par administration d'une anthocyanine ou d'une anthocyanidine ou d'un métabolite associé. En particulier, l'invention concerne l'acide protocatéchuique (RCA) ou le 2,4,6-trihydroxybenzaldéhyde (2,4,6 THBA) destiné à être utilisé dans le traitement d'un implant infecté ou d'une autre surface chez un patient.
CA3106105A 2018-08-08 2019-08-08 Methodes de diagnostic et de traitement d'implants infectes Pending CA3106105A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/058,909 2018-08-08
US16/058,909 US10398664B2 (en) 2013-05-01 2018-08-08 Methods of diagnosing and treating infected implants
PCT/US2019/045693 WO2020033677A1 (fr) 2018-08-08 2019-08-08 Méthodes de diagnostic et de traitement d'implants infectés

Publications (1)

Publication Number Publication Date
CA3106105A1 true CA3106105A1 (fr) 2020-02-13

Family

ID=67766329

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3106105A Pending CA3106105A1 (fr) 2018-08-08 2019-08-08 Methodes de diagnostic et de traitement d'implants infectes

Country Status (2)

Country Link
CA (1) CA3106105A1 (fr)
WO (1) WO2020033677A1 (fr)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5496306A (en) 1990-09-21 1996-03-05 Light Age, Inc. Pulse stretched solid-state laser lithotripter
AU2638795A (en) 1994-06-17 1996-01-15 University Of Nebraska Board Of Regents In situ gel-forming delivery vehicle for bio-affecting substances, and method of use
US6123679A (en) 1996-08-29 2000-09-26 Lafaut; Jean-Pierre Method for extracorporeal shock wave lithotripsy by applying an acoustic shock wave followed by a limited oscillating acoustic pressure wave train
US6770039B2 (en) 2001-11-09 2004-08-03 Duke University Method to reduce tissue injury in shock wave lithotripsy
DE60232987D1 (de) 2001-11-14 2009-08-27 Durect Corp Injizierbare depotzusammensetzungen
US7522955B2 (en) * 2003-10-03 2009-04-21 Michael Rontal Method and apparatus for the ultrasonic cleaning of biofilm coated surfaces
US9498413B2 (en) * 2013-05-01 2016-11-22 Lanny Leo Johnson Antimicrobials and methods of use thereof for wound healing
CA2936453A1 (fr) * 2014-01-09 2015-07-16 Axiosonic, Llc Systemes et methodes utilisant des ultrasons pour un traitement
WO2018191409A1 (fr) * 2017-04-11 2018-10-18 Lanny Leo Johnson Agents antimicrobiens et leurs procédés d'utilisation

Also Published As

Publication number Publication date
WO2020033677A1 (fr) 2020-02-13

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