CA3104504A1 - Traitement d'une maladie demyelinisante - Google Patents
Traitement d'une maladie demyelinisante Download PDFInfo
- Publication number
- CA3104504A1 CA3104504A1 CA3104504A CA3104504A CA3104504A1 CA 3104504 A1 CA3104504 A1 CA 3104504A1 CA 3104504 A CA3104504 A CA 3104504A CA 3104504 A CA3104504 A CA 3104504A CA 3104504 A1 CA3104504 A1 CA 3104504A1
- Authority
- CA
- Canada
- Prior art keywords
- optionally
- optionally substituted
- mlkl
- purine
- dione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne des procédés d'inhibition ou de traitement de la démyélinisation (ou de traitement d'une maladie démyélinisante) comprenant l'administration à une personne qui en a besoin d'un inhibiteur de MLKL.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNPCT/CN2018/091744 | 2018-06-19 | ||
CN2018091744 | 2018-06-19 | ||
PCT/CN2019/091478 WO2019242576A1 (fr) | 2018-06-19 | 2019-06-17 | Traitement d'une maladie démyélinisante |
Publications (1)
Publication Number | Publication Date |
---|---|
CA3104504A1 true CA3104504A1 (fr) | 2019-12-26 |
Family
ID=68983504
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA3104504A Abandoned CA3104504A1 (fr) | 2018-06-19 | 2019-06-17 | Traitement d'une maladie demyelinisante |
Country Status (2)
Country | Link |
---|---|
CA (1) | CA3104504A1 (fr) |
WO (1) | WO2019242576A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024050825A1 (fr) * | 2022-09-09 | 2024-03-14 | National Institute Of Biological Sciences, Beijing | Composés utilisés en tant qu'inhibiteurs de mlkl |
-
2019
- 2019-06-17 WO PCT/CN2019/091478 patent/WO2019242576A1/fr active Application Filing
- 2019-06-17 CA CA3104504A patent/CA3104504A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2019242576A1 (fr) | 2019-12-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request |
Effective date: 20201218 |
|
FZDE | Discontinued |
Effective date: 20221219 |
|
FZDE | Discontinued |
Effective date: 20221219 |