CA3080835A1 - Methodes immunotherapeutiques pour traiter et/ou prevenir le cancer du poumon - Google Patents
Methodes immunotherapeutiques pour traiter et/ou prevenir le cancer du poumon Download PDFInfo
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Abstract
La présente invention concerne le traitement et le diagnostic du cancer du poumon et de métastases de celui-ci. Plus spécifiquement, l'invention concerne une telle utilisation thérapeutique de sources d'antigène fournissant des polypeptides immunogènes comprenant au moins une partie immunogène d'une protéine associée à une cellule cancéreuse, qui est, de préférence, une protéine de la zone pellucide (ZP), en particulier une protéine ZP3 ou le domaine extracellulaire de celle-ci, moyennant quoi la source d'antigène induit une réponse immunitaire cellulaire contre les cellules du cancer du poumon. La source d'antigène peut être une composition protéinique comprenant un tel polypeptide ZP immunogène, un acide nucléique codant pour le polypeptide ZP immunogène, ou une cellule exprimant ou présentant le polypeptide ZP immunogène. De plus, l'invention concerne l'utilisation thérapeutique d'un lymphocyte T comprenant un récepteur de lymphocyte T qui se lie à un complexe CMH-peptide, le peptide étant un peptide provenant du polypeptide ZP immunogène. L'invention concerne en outre l'utilisation thérapeutique et/ou diagnostique d'anticorps qui se lient de manière spécifique au polypeptide ZP immunogène.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17199441 | 2017-10-31 | ||
| EP17199441.1 | 2017-10-31 | ||
| PCT/EP2018/079802 WO2019086507A1 (fr) | 2017-10-31 | 2018-10-31 | Méthodes immunothérapeutiques pour traiter et/ou prévenir le cancer du poumon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3080835A1 true CA3080835A1 (fr) | 2019-05-09 |
Family
ID=60421550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3080835A Pending CA3080835A1 (fr) | 2017-10-31 | 2018-10-31 | Methodes immunotherapeutiques pour traiter et/ou prevenir le cancer du poumon |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11819542B2 (fr) |
| EP (1) | EP3703734A1 (fr) |
| CN (1) | CN111511392A (fr) |
| BR (1) | BR112020008512A2 (fr) |
| CA (1) | CA3080835A1 (fr) |
| WO (1) | WO2019086507A1 (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210317165A1 (en) * | 2018-09-03 | 2021-10-14 | Laboratoire Hra-Pharma | Zp3 fragments in immunotherapy of ovarian cancer |
| WO2023066923A1 (fr) | 2021-10-19 | 2023-04-27 | Rahman Nafis | Contraception masculine |
| WO2023237726A1 (fr) * | 2022-06-10 | 2023-12-14 | Pantarhei Oncology B.V. | Variant intracellulaire spécifique d'une tumeur de la glycoprotéine 3 de la membrane pellucide humaine et acides nucléiques codant pour celui-ci pour utilisation dans le traitement du cancer |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2777890B1 (fr) | 1998-04-22 | 2000-12-29 | Roussy Inst Gustave | Composes peptidiques d'hsp70 utiles dans l'immunotherapie du cancer |
| US7202034B2 (en) | 2000-12-08 | 2007-04-10 | Academisch Ziekenhuis Leiden | Long peptides of 22-45 amino acid residues that induce and/or enhance antigen specific immune responses |
| AR056245A1 (es) | 2003-06-19 | 2007-10-03 | Bestewil Holding Bv | Membranas virales reconstituidas funcionales que contienen un coadyuvante |
| EP2281030B1 (fr) | 2008-05-19 | 2017-01-04 | DCPrime B.V. | Procédé d'induction et d'accélération de cellules |
| CA2809153C (fr) | 2010-08-27 | 2023-09-26 | Pantarhei Bioscience B.V. | Utilisation de glycoproteine hzp3 en vue de traiter le cancer de la prostate |
| WO2013087083A1 (fr) | 2011-12-15 | 2013-06-20 | Biontech Ag | Particules comprenant un arn simple brin et un arn double brin à des fins d'immunomodulation |
| NL2009102C2 (en) | 2012-07-02 | 2014-01-06 | Dcprime B V | Method for dc-loading. |
| EP2743344A1 (fr) | 2012-12-11 | 2014-06-18 | DCPrime B.V. | Vaccins anticancéreux thérapeutiques dérivés d'une nouvelle lignée de cellules dendritiques |
| EP3586870A1 (fr) | 2013-03-12 | 2020-01-01 | The Trustees Of The University Of Pennsylvania | Vaccins améliorés pour le papillomavirus humain et leurs procédés d'utilisation |
| MA39849A (fr) | 2014-04-24 | 2017-03-01 | Advaxis Inc | Souches de listeria utilisées comme vaccin recombinant et procédé de production |
| EP3186277B1 (fr) | 2014-08-27 | 2020-10-07 | Memorial Sloan Kettering Cancer Center | Anticorps, compositions et leurs utilisations |
| CA2974956A1 (fr) | 2015-01-29 | 2016-08-04 | The Trustees Of The University Of Pennsylvania | Associations d'inhibiteurs de point de controle immunitaires et de vaccins, et leur utilisation en immunotherapie |
| GB201521894D0 (en) * | 2015-12-11 | 2016-01-27 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against various cancers |
| KR20180108793A (ko) | 2016-02-05 | 2018-10-04 | 이노비오 파마수티컬즈, 인크. | 암 백신 및 이를 이용하는 치료 방법 |
| US20190307868A1 (en) | 2016-03-31 | 2019-10-10 | Neon Therapeutics, Inc. | Neoantigens and methods of their use |
-
2018
- 2018-10-31 CN CN201880083511.0A patent/CN111511392A/zh active Pending
- 2018-10-31 CA CA3080835A patent/CA3080835A1/fr active Pending
- 2018-10-31 BR BR112020008512-0A patent/BR112020008512A2/pt unknown
- 2018-10-31 WO PCT/EP2018/079802 patent/WO2019086507A1/fr unknown
- 2018-10-31 US US16/760,457 patent/US11819542B2/en active Active
- 2018-10-31 EP EP18795630.5A patent/EP3703734A1/fr active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BR112020008512A2 (pt) | 2020-10-06 |
| US20200276291A1 (en) | 2020-09-03 |
| RU2020117746A (ru) | 2021-12-01 |
| EP3703734A1 (fr) | 2020-09-09 |
| CN111511392A (zh) | 2020-08-07 |
| WO2019086507A1 (fr) | 2019-05-09 |
| US11819542B2 (en) | 2023-11-21 |
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