CA3076858A1 - Process for preparing a platelet lysate fraction, platelet lysate fraction and its use for treating disorders of the central nervous system - Google Patents

Process for preparing a platelet lysate fraction, platelet lysate fraction and its use for treating disorders of the central nervous system Download PDF

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Publication number
CA3076858A1
CA3076858A1 CA3076858A CA3076858A CA3076858A1 CA 3076858 A1 CA3076858 A1 CA 3076858A1 CA 3076858 A CA3076858 A CA 3076858A CA 3076858 A CA3076858 A CA 3076858A CA 3076858 A1 CA3076858 A1 CA 3076858A1
Authority
CA
Canada
Prior art keywords
platelet lysate
fraction
platelet
kda
lysate fraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3076858A
Other languages
English (en)
French (fr)
Inventor
David DeVos
Thierry Burnouf
Jean-christophe Devedjian
Ming-Li Chou
Flore GOUEL
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Centre Hospitalier Regional Universitaire de Lille CHRU
Universite du Littoral Cote dOpale
Universite de Lille
Taipei Medical University TMU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM, Centre Hospitalier Regional Universitaire de Lille CHRU, Universite du Littoral Cote dOpale, Universite de Lille, Taipei Medical University TMU filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Publication of CA3076858A1 publication Critical patent/CA3076858A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0644—Platelets; Megakaryocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CA3076858A 2017-09-27 2018-09-27 Process for preparing a platelet lysate fraction, platelet lysate fraction and its use for treating disorders of the central nervous system Pending CA3076858A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17306284.5 2017-09-27
EP17306284 2017-09-27
PCT/EP2018/076244 WO2019063683A1 (en) 2017-09-27 2018-09-27 PROCESS FOR THE PREPARATION OF PLATELET LYSATE FRACTION, PLATELET LYSATE FRACTION AND USE THEREOF FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS

Publications (1)

Publication Number Publication Date
CA3076858A1 true CA3076858A1 (en) 2019-04-04

Family

ID=60083230

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3076858A Pending CA3076858A1 (en) 2017-09-27 2018-09-27 Process for preparing a platelet lysate fraction, platelet lysate fraction and its use for treating disorders of the central nervous system

Country Status (11)

Country Link
US (1) US20230135837A1 (https=)
EP (1) EP3687554A1 (https=)
JP (1) JP2020535163A (https=)
CN (1) CN111107857A (https=)
AU (1) AU2018343875A1 (https=)
BR (1) BR112020006316A2 (https=)
CA (1) CA3076858A1 (https=)
IL (1) IL273482A (https=)
RU (1) RU2020112898A (https=)
TW (1) TW201914595A (https=)
WO (1) WO2019063683A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2840568C (en) * 2011-06-27 2021-05-04 Emory University Compositions, uses, and preparation of platelet lysates
TWI744300B (zh) * 2016-03-23 2021-11-01 里爾中央醫學中心 改良性熱處理的血小板顆粒裂解液在製備用於治療神經系統疾病的組合物的用途
US12570962B2 (en) * 2020-02-03 2026-03-10 Oklahoma Blood Institute Preparation of human platelet lysate (HPL) from refrigerated whole blood platelets
EP3881858A1 (en) * 2020-03-20 2021-09-22 Rok Pangersic Heat-treated platelet-derived growth factor extract for use in a method of preventing or treating a tissue defect

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4815063B2 (ja) * 2001-04-13 2011-11-16 きみ子 室伏 環状ホスファチジン酸を含むグリア細胞の増殖、分化及び／又は生存の促進のための薬剤
SE0501462L (sv) * 2005-06-23 2006-09-26 Proliff Ab Förfarande för framställning av blodplättslysat
JP5383498B2 (ja) * 2006-12-14 2014-01-08 ニューロノバ エービー メラノコルチン４レセプターの活性を低下させる薬剤を使用した、神経系の疾患または損傷の処置
ES2402144T3 (es) * 2010-05-25 2013-04-29 Gwowei Technology Co., Ltd. Lisado plaquetario inactivado que contiene factores de crecimiento empobrecido en PDGF y VEGF y su procedimiento de preparación
EP3107590B1 (en) * 2014-02-20 2021-11-17 Ortho Regenerative Technologies Inc. Freeze-dried polymer compositions for mixing with platelet rich plasma to form implants for tissue repair and/or compositions for therapeutic intra-articular injections
EP3143130B1 (en) * 2014-05-16 2024-03-06 Mayo Foundation for Medical Education and Research Cell culture media compositions for primary cells

Also Published As

Publication number Publication date
JP2020535163A (ja) 2020-12-03
WO2019063683A1 (en) 2019-04-04
TW201914595A (zh) 2019-04-16
CN111107857A (zh) 2020-05-05
EP3687554A1 (en) 2020-08-05
RU2020112898A (ru) 2021-10-04
BR112020006316A2 (pt) 2020-09-24
US20230135837A1 (en) 2023-05-04
AU2018343875A1 (en) 2020-04-16
IL273482A (en) 2020-05-31

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