CA3075371A1 - Potentiating the effect of atp release - Google Patents
Potentiating the effect of atp release Download PDFInfo
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- CA3075371A1 CA3075371A1 CA3075371A CA3075371A CA3075371A1 CA 3075371 A1 CA3075371 A1 CA 3075371A1 CA 3075371 A CA3075371 A CA 3075371A CA 3075371 A CA3075371 A CA 3075371A CA 3075371 A1 CA3075371 A1 CA 3075371A1
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (7)
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| US201762586224P | 2017-11-15 | 2017-11-15 | |
| US62/586,224 | 2017-11-15 | ||
| US201862686149P | 2018-06-18 | 2018-06-18 | |
| US62/686,149 | 2018-06-18 | ||
| US201862733175P | 2018-09-19 | 2018-09-19 | |
| US62/733,175 | 2018-09-19 | ||
| PCT/EP2018/081364 WO2019096900A1 (en) | 2017-11-15 | 2018-11-15 | Potentiating the effect of atp release |
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| CA3075371A1 true CA3075371A1 (en) | 2019-05-23 |
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| EP (1) | EP3710052A1 (enExample) |
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| PT2238170T (pt) | 2008-01-31 | 2017-02-21 | Inserm - Inst Nat De La Santé Et De La Rech Médicale | Anticorpos contra cd39 humano e seu uso para inibição da actividade de células t reguladoras |
| IL269150B2 (en) | 2017-03-16 | 2025-04-01 | Innate Pharma | Cancer treatment preparations and methods |
| WO2018209324A2 (en) | 2017-05-11 | 2018-11-15 | The Broad Institute, Inc. | Methods and compositions of use of cd8+ tumor infiltrating lymphocyte subtypes and gene signatures thereof |
| JP7113071B2 (ja) | 2017-07-31 | 2022-08-04 | トリシュラ セラピューティクス， インコーポレイテッド | 抗ｃｄ３９抗体、抗ｃｄ３９抗体を含む組成物、および抗ｃｄ３９抗体を使用する方法 |
| SG11202002192QA (en) * | 2017-10-06 | 2020-04-29 | Innate Pharma | Restoration of t cell activity via the cd39/cd73 axis |
| MX2020011588A (es) | 2018-05-03 | 2020-12-07 | Shanghai Epimab Biotherapeutics Co Ltd | Anticuerpos de alta afinidad a pd-1 y lag-3 y proteinas de union bispecificas preparadas a partir de las mismas. |
| TWI870353B (zh) | 2018-06-18 | 2025-01-21 | 法商天賜製藥公司 | 用於治療癌症之組合物及方法 |
| CN110407941B (zh) * | 2019-09-25 | 2020-01-14 | 上海岸迈生物科技有限公司 | Cd39的高亲和力抗体及其用途 |
| TW202118791A (zh) | 2019-11-05 | 2021-05-16 | 大陸商北京加科思新藥研發有限公司 | 對cd39具有特異性的結合分子及其用途 |
| KR102856075B1 (ko) | 2020-07-17 | 2025-09-04 | 삼성전자주식회사 | 비휘발성 메모리 장치 및 그 동작 방법 |
| CN115975030B (zh) * | 2021-09-30 | 2023-09-26 | 杭州邦顺制药有限公司 | 抗cd39抗体-药物偶联物及其用途 |
| CN119569881B (zh) | 2022-03-03 | 2025-11-07 | 艾库斯生物科学有限公司 | 抗cd39抗体及其用途 |
| US20250188165A1 (en) * | 2022-03-04 | 2025-06-12 | Trishula Therapeutics Inc | Combinations with an anti human cd39 antibody, an anti human pd-1 antibody, and chemotherapy in gastric cancer |
| CN117903311B (zh) * | 2024-03-20 | 2024-10-25 | 湖南卓润生物科技有限公司 | sST2特异性结合蛋白及其制备方法和应用 |
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| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
| US5660827A (en) | 1992-03-05 | 1997-08-26 | Board Of Regents, The University Of Texas System | Antibodies that bind to endoglin |
| PT2238170T (pt) | 2008-01-31 | 2017-02-21 | Inserm - Inst Nat De La Santé Et De La Rech Médicale | Anticorpos contra cd39 humano e seu uso para inibição da actividade de células t reguladoras |
| US10766966B2 (en) * | 2014-10-10 | 2020-09-08 | Innate Pharma | CD73 blockade |
| EP3215538A4 (en) * | 2014-11-07 | 2018-07-04 | Igenica Biotherapeutics, Inc. | Anti-cd39 antibodies and uses thereof |
| US20190153113A1 (en) * | 2015-11-23 | 2019-05-23 | Innate Pharma | Cd39 vascular isoform targeting agents |
| EP3912681A1 (en) | 2016-03-14 | 2021-11-24 | Orega Biotech | Anti-cd39 antibodies |
| IL269150B2 (en) * | 2017-03-16 | 2025-04-01 | Innate Pharma | Cancer treatment preparations and methods |
| KR102495666B1 (ko) * | 2018-03-14 | 2023-02-06 | 서피스 온콜로지, 인크. | Cd39에 결합하는 항체 및 이의 용도 |
-
2018
- 2018-11-15 CN CN201880070859.6A patent/CN111372606B/zh active Active
- 2018-11-15 EP EP18803967.1A patent/EP3710052A1/en active Pending
- 2018-11-15 BR BR112020009655A patent/BR112020009655A8/pt unknown
- 2018-11-15 JP JP2020526482A patent/JP7383609B2/ja active Active
- 2018-11-15 KR KR1020207013452A patent/KR102781619B1/ko active Active
- 2018-11-15 WO PCT/EP2018/081364 patent/WO2019096900A1/en not_active Ceased
- 2018-11-15 CA CA3075371A patent/CA3075371A1/en active Pending
- 2018-11-15 AU AU2018368541A patent/AU2018368541B2/en active Active
- 2018-11-15 SG SG11202002195YA patent/SG11202002195YA/en unknown
-
2019
- 2019-03-29 US US16/370,789 patent/US20190218304A1/en not_active Abandoned
-
2020
- 2020-03-19 IL IL273440A patent/IL273440A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20190218304A1 (en) | 2019-07-18 |
| CN111372606B (zh) | 2024-02-20 |
| KR20200088811A (ko) | 2020-07-23 |
| BR112020009655A2 (pt) | 2020-10-13 |
| BR112020009655A8 (pt) | 2023-03-21 |
| IL273440A (en) | 2020-05-31 |
| CN111372606A (zh) | 2020-07-03 |
| KR102781619B1 (ko) | 2025-03-14 |
| JP2021502980A (ja) | 2021-02-04 |
| AU2018368541A1 (en) | 2020-03-19 |
| JP7383609B2 (ja) | 2023-11-20 |
| SG11202002195YA (en) | 2020-04-29 |
| WO2019096900A1 (en) | 2019-05-23 |
| AU2018368541B2 (en) | 2025-06-12 |
| EP3710052A1 (en) | 2020-09-23 |
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