CA3068008A1 - Hemofilter for in vivo blood filtration - Google Patents

Hemofilter for in vivo blood filtration Download PDF

Info

Publication number
CA3068008A1
CA3068008A1 CA3068008A CA3068008A CA3068008A1 CA 3068008 A1 CA3068008 A1 CA 3068008A1 CA 3068008 A CA3068008 A CA 3068008A CA 3068008 A CA3068008 A CA 3068008A CA 3068008 A1 CA3068008 A1 CA 3068008A1
Authority
CA
Canada
Prior art keywords
hemofilter
section
filtration
region
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3068008A
Other languages
English (en)
French (fr)
Inventor
Shuvo Roy
William FISSELL
Nathan WRIGHT
Mark Goodin
Steven Goebel
Amanda BUCK
Joey GROSZEK
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vanderbilt University
University of California, San Diego
Original Assignee
Vanderbilt University
University of California, San Diego
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vanderbilt University, University of California, San Diego filed Critical Vanderbilt University
Publication of CA3068008A1 publication Critical patent/CA3068008A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A61M1/1631—Constructional aspects thereof having non-tubular membranes, e.g. sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165—Filtering accessories, e.g. blood filters, filters for infusion liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/082—Flat membrane modules comprising a stack of flat membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/082—Flat membrane modules comprising a stack of flat membranes
    • B01D63/084—Flat membrane modules comprising a stack of flat membranes at least one flow duct intersecting the membranes
    • B01D63/085—Flat membrane modules comprising a stack of flat membranes at least one flow duct intersecting the membranes specially adapted for two fluids in mass exchange flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1678—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes intracorporal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/04—General characteristics of the apparatus implanted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3334—Measuring or controlling the flow rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/11—Laminar flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/10—Specific supply elements
    • B01D2313/105—Supply manifolds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/12—Specific discharge elements
    • B01D2313/125—Discharge manifolds
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28—HEAT EXCHANGE IN GENERAL
    • F28F—DETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F9/00—Casings; Header boxes; Auxiliary supports for elements; Auxiliary members within casings
    • F28F9/02—Header boxes; End plates
    • F28F2009/0285—Other particular headers or end plates
    • F28F2009/029—Other particular headers or end plates with increasing or decreasing cross-section, e.g. having conical shape

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • External Artificial Organs (AREA)
CA3068008A 2017-06-21 2018-06-20 Hemofilter for in vivo blood filtration Pending CA3068008A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762523131P 2017-06-21 2017-06-21
US62/523,131 2017-06-21
PCT/US2018/038548 WO2018237036A1 (en) 2017-06-21 2018-06-20 HEMOFILTER FOR IN VIVO BLOOD FILTRATION

Publications (1)

Publication Number Publication Date
CA3068008A1 true CA3068008A1 (en) 2018-12-27

Family

ID=64736140

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3068008A Pending CA3068008A1 (en) 2017-06-21 2018-06-20 Hemofilter for in vivo blood filtration

Country Status (7)

Country Link
US (3) US11511027B2 (enExample)
EP (2) EP3641846B1 (enExample)
JP (1) JP7516049B2 (enExample)
AU (1) AU2018289514B2 (enExample)
CA (1) CA3068008A1 (enExample)
SG (1) SG11201912800RA (enExample)
WO (1) WO2018237036A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10874786B2 (en) * 2017-05-31 2020-12-29 Nephrodite LLC Implantable dialysis device
US11511027B2 (en) * 2017-06-21 2022-11-29 The Regents Of The University Of California Hemofilter for in vivo blood filtration
AU2019269683B2 (en) 2018-05-18 2024-11-14 The Regents Of The University Of California In vivo blood filtration membranes and devices
EP4085940A1 (en) 2021-05-07 2022-11-09 Imec VZW A method and a maintenance device for automatic maintenance of an autonomous dialysis system
WO2026096430A1 (en) * 2024-10-28 2026-05-07 The Regents Of The University Of California Hemofiltration devices with flow diverters and recesses

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038191A (en) 1975-10-14 1977-07-26 Davis Harold R Manifold for ultra filtration machine
JPS56104673A (en) * 1980-01-23 1981-08-20 Otsubo Osamu Internally buried artificial kidney
FR2495006A1 (fr) * 1980-11-12 1982-06-04 Sartorius Gmbh Dispositif a trois chambres d'ecoulement pour le transfert de masses entre des fluides
JP4084869B2 (ja) * 1997-11-10 2008-04-30 保博 山本 体内留置型浄化装置
US6561996B1 (en) 1998-05-19 2003-05-13 Transvivo, Inc. Apparatus and method for in vivo hemodialysis
JP2002523196A (ja) 1998-08-28 2002-07-30 ソレンソン ディベロップメント インコーポレイテッド 自己プライミング透析フィルタ
DE10049256A1 (de) 2000-10-05 2002-04-11 Behr Gmbh & Co Serpentinen-Wärmeübertrager
US8038639B2 (en) 2004-11-04 2011-10-18 Baxter International Inc. Medical fluid system with flexible sheeting disposable unit
US20070246106A1 (en) 2006-04-25 2007-10-25 Velocys Inc. Flow Distribution Channels To Control Flow in Process Channels
EP2125171A4 (en) 2007-01-10 2012-05-16 Univ Michigan ULTRAFILTRATION MEMBRANE, DEVICE, BIOARTIFICIAL ORGAN AND CORRESPONDING METHOD
JP2009131573A (ja) * 2007-11-28 2009-06-18 Daiki Iwami 体内完全埋め込み型の人工腎臓の構成および使用法
JP2010069278A (ja) * 2008-09-22 2010-04-02 成一 ▲高▼杉 体内に埋め込み可能な体液浄化装置
US9017277B2 (en) * 2011-05-02 2015-04-28 Medtronic, Inc. System and implantable device for treating chronic kidney disease
US11511027B2 (en) * 2017-06-21 2022-11-29 The Regents Of The University Of California Hemofilter for in vivo blood filtration

Also Published As

Publication number Publication date
EP3641846A1 (en) 2020-04-29
EP4600600A3 (en) 2025-11-12
US20230173156A1 (en) 2023-06-08
US11511027B2 (en) 2022-11-29
US12318522B2 (en) 2025-06-03
EP4600600A2 (en) 2025-08-13
EP3641846B1 (en) 2025-10-15
JP2020524581A (ja) 2020-08-20
US11957824B2 (en) 2024-04-16
US20200114058A1 (en) 2020-04-16
WO2018237036A1 (en) 2018-12-27
SG11201912800RA (en) 2020-01-30
US20240399041A1 (en) 2024-12-05
JP7516049B2 (ja) 2024-07-16
AU2018289514B2 (en) 2023-11-23
AU2018289514A1 (en) 2020-01-16
EP3641846A4 (en) 2021-03-17

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