CA3060570A1 - Therapeutic genome editing in wiskott-aldrich syndrome and x-linked thrombocytopenia - Google Patents
Therapeutic genome editing in wiskott-aldrich syndrome and x-linked thrombocytopenia Download PDFInfo
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- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
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| CN115927585A (zh) * | 2022-08-29 | 2023-04-07 | 湖南家辉生物技术有限公司 | WAS致病突变基因及在制备Wiskott-Aldrich综合征诊断试剂盒中的应用 |
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| WO2020150499A1 (en) * | 2019-01-16 | 2020-07-23 | Fred Hutchinson Cancer Research Center | Methods to tag and isolate cells infected with the human immunodeficiency virus |
| WO2021062267A1 (en) * | 2019-09-26 | 2021-04-01 | Nantbio, Inc. | Primary t-cell expansion |
| EP4058587A4 (en) * | 2019-11-11 | 2024-03-20 | The Regents Of The University Of California | Lentiviral vectors in hematopoietic stem cells to treat wiskott-aldrich syndrome (was) |
| CN111808859B (zh) * | 2020-07-13 | 2022-09-13 | 中国科学院广州生物医药与健康研究院 | WAS基因的gRNA及其应用 |
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| WO2015048577A2 (en) * | 2013-09-27 | 2015-04-02 | Editas Medicine, Inc. | Crispr-related methods and compositions |
| CN110713995B (zh) * | 2013-10-17 | 2023-08-01 | 桑格摩生物科学股份有限公司 | 用于核酸酶介导的基因组工程改造的递送方法和组合物 |
| EP3204496A1 (en) * | 2014-10-10 | 2017-08-16 | Editas Medicine, Inc. | Compositions and methods for promoting homology directed repair |
| JP7059179B2 (ja) * | 2015-10-20 | 2022-04-25 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 遺伝子操作のための方法及び製品 |
| WO2018058064A1 (en) * | 2016-09-23 | 2018-03-29 | Casebia Therapeutics Limited Liability Partnership | Compositions and methods for gene editing |
| US20200206322A1 (en) * | 2017-03-21 | 2020-07-02 | Stitch Bio, Llc | Treating cancer with cas endonuclease complexes |
| JP2020517270A (ja) * | 2017-04-21 | 2020-06-18 | シアトル チルドレンズ ホスピタル， ディービーエー シアトル チルドレンズ リサーチ インスティテュート | ウィスコット・アルドリッチ症候群およびｘ連鎖性血小板減少症の治療的ゲノム編集 |
| AU2019261385A1 (en) * | 2018-04-27 | 2020-11-19 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Therapeutic genome editing in X-linked hyper IgM syndrome |
| WO2019210216A2 (en) | 2018-04-27 | 2019-10-31 | Seattle Children's Hospital D/B/A Seattle Children's Research Institute | Talen-based and crispr/cas-based gene editing for bruton's tyrosine kinase |
| US11521964B2 (en) | 2018-06-29 | 2022-12-06 | Intel Corporation | Schottky diode structures and integration with III-V transistors |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115927585A (zh) * | 2022-08-29 | 2023-04-07 | 湖南家辉生物技术有限公司 | WAS致病突变基因及在制备Wiskott-Aldrich综合征诊断试剂盒中的应用 |
| CN115927585B (zh) * | 2022-08-29 | 2024-04-23 | 湖南家辉生物技术有限公司 | WAS致病突变基因及在制备Wiskott-Aldrich综合征诊断试剂盒中的应用 |
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| US20200325494A1 (en) | 2020-10-15 |
| US11643671B2 (en) | 2023-05-09 |
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