CA3044270A1 - The use of trimetazidine in the prevention and/or treatment of contrast-induced acute kidney injury____ - Google Patents
The use of trimetazidine in the prevention and/or treatment of contrast-induced acute kidney injury____ Download PDFInfo
- Publication number
- CA3044270A1 CA3044270A1 CA3044270A CA3044270A CA3044270A1 CA 3044270 A1 CA3044270 A1 CA 3044270A1 CA 3044270 A CA3044270 A CA 3044270A CA 3044270 A CA3044270 A CA 3044270A CA 3044270 A1 CA3044270 A1 CA 3044270A1
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- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- trimetazidine
- patient
- administered
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US62/424,771 | 2016-11-21 | ||
| PCT/US2017/062771 WO2018094387A1 (en) | 2016-11-21 | 2017-11-21 | Prevention and/or treatment of contrast-induced acute kidney injury |
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| CA3044270A1 true CA3044270A1 (en) | 2018-05-24 |
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| US11123345B2 (en) | 2016-11-21 | 2021-09-21 | Saghmos Therapeutics, Inc. | Prevention and/or treatment of contrast-induced acute kidney injury |
| WO2019161309A1 (en) * | 2018-02-19 | 2019-08-22 | Martin Pharmaceuticals Inc. | Stable oral liquid formulation of trimetazidine |
| WO2025137462A1 (en) * | 2023-12-21 | 2025-06-26 | Numiera Therapeutics Inc. | Combination therapy for cancer |
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| FR2490963B1 (fr) * | 1980-09-30 | 1986-04-18 | Science Union & Cie | Nouvelle composition therapeutique a action anti-ischemique contenant de la trimethoxy 2, 3, 4-benzyl 1-piperazine |
| US20080059228A1 (en) | 2004-04-24 | 2008-03-06 | Christopher Bossi | Operation Of A Remote Medication Management System |
| WO2008057534A2 (en) | 2006-11-07 | 2008-05-15 | University Of Vermont And State Agricultural College | Methods and compositions for organ protection |
| GB2462947A (en) | 2007-03-09 | 2010-03-03 | Symcopeia Company | Fatty Acid Oxidation Inhibitors Treating Hyperglycemia and Related Disorders. |
| BRPI0815602A2 (pt) | 2007-08-08 | 2015-03-03 | Usv Ltd | Composições de liberação prolongada de trimetazidina e processo para a preparação das mesmas |
| EP2200591A2 (en) | 2007-09-11 | 2010-06-30 | Ranbaxy Laboratories Limited | Controlled release pharmaceutical dosage forms of trimetazidine |
| US20090257999A1 (en) | 2007-12-31 | 2009-10-15 | Inotek Pharmaceuticals Corporation | Method of preventing contrast-induced nephropathy |
| US8143219B2 (en) * | 2008-02-26 | 2012-03-27 | Cornell University | Methods for prevention and treatment of acute renal injury |
| JP2013506681A (ja) | 2009-10-02 | 2013-02-28 | バクスター・インターナショナル・インコーポレイテッド | 腎損傷の処置における使用のための造血幹細胞 |
| US9271952B2 (en) | 2011-10-11 | 2016-03-01 | Complexa, Inc. | Compositions and methods for treating nephropathy |
| FR2986431B1 (fr) | 2012-02-03 | 2017-03-17 | Servier Lab | Composition pharmaceutique a liberation prolongee de trimetazidine, son procede de fabrication et son utilisation dans des traitements therapeutiques |
| US11123345B2 (en) | 2016-11-21 | 2021-09-21 | Saghmos Therapeutics, Inc. | Prevention and/or treatment of contrast-induced acute kidney injury |
| WO2018129045A1 (en) | 2017-01-03 | 2018-07-12 | Saghmos Therapeutics, Inc. | Methods of improving patient compliance to treat contrast-induced injury |
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- 2017-11-21 WO PCT/US2017/062771 patent/WO2018094387A1/en not_active Ceased
- 2017-11-21 EP EP17872053.8A patent/EP3525771A4/en not_active Withdrawn
- 2017-11-21 MX MX2019005782A patent/MX2019005782A/es unknown
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Also Published As
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|---|---|
| JP2022059054A (ja) | 2022-04-12 |
| EP4378457A2 (en) | 2024-06-05 |
| EP4378457A3 (en) | 2024-07-31 |
| US20250073227A1 (en) | 2025-03-06 |
| JP2024028652A (ja) | 2024-03-04 |
| JP7474463B2 (ja) | 2024-04-25 |
| US11123345B2 (en) | 2021-09-21 |
| JP2019535830A (ja) | 2019-12-12 |
| US20210401832A1 (en) | 2021-12-30 |
| EP3525771A1 (en) | 2019-08-21 |
| MX2019005782A (es) | 2019-08-29 |
| WO2018094387A1 (en) | 2018-05-24 |
| US20180140599A1 (en) | 2018-05-24 |
| US20190365740A1 (en) | 2019-12-05 |
| EP3525771A4 (en) | 2020-05-27 |
| US11986473B2 (en) | 2024-05-21 |
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