CA3044261A1 - Steroid administration and immunotherapy - Google Patents

Steroid administration and immunotherapy Download PDF

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Publication number
CA3044261A1
CA3044261A1 CA3044261A CA3044261A CA3044261A1 CA 3044261 A1 CA3044261 A1 CA 3044261A1 CA 3044261 A CA3044261 A CA 3044261A CA 3044261 A CA3044261 A CA 3044261A CA 3044261 A1 CA3044261 A1 CA 3044261A1
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CA
Canada
Prior art keywords
steroid
cell
administered
amount
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3044261A
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English (en)
French (fr)
Inventor
Laurence J.N. Cooper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Precigen Inc
Original Assignee
Intrexon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intrexon Corp filed Critical Intrexon Corp
Publication of CA3044261A1 publication Critical patent/CA3044261A1/en
Pending legal-status Critical Current

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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
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    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
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    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

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  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Developmental Biology & Embryology (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
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CA3044261A 2016-11-30 2017-11-30 Steroid administration and immunotherapy Pending CA3044261A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662428474P 2016-11-30 2016-11-30
US62/428,474 2016-11-30
PCT/US2017/064060 WO2018102606A1 (en) 2016-11-30 2017-11-30 Steroid administration and immunotherapy

Publications (1)

Publication Number Publication Date
CA3044261A1 true CA3044261A1 (en) 2018-06-07

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Application Number Title Priority Date Filing Date
CA3044261A Pending CA3044261A1 (en) 2016-11-30 2017-11-30 Steroid administration and immunotherapy

Country Status (8)

Country Link
US (1) US20190351019A1 (OSRAM)
EP (1) EP3548047A4 (OSRAM)
JP (1) JP2019536786A (OSRAM)
KR (1) KR20190090390A (OSRAM)
CN (1) CN110234327A (OSRAM)
AU (1) AU2017368248A1 (OSRAM)
CA (1) CA3044261A1 (OSRAM)
WO (1) WO2018102606A1 (OSRAM)

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WO2022016150A1 (en) * 2020-07-17 2022-01-20 Ross Peter M Methods for the treatment of cytokine release syndromes
WO2022109611A1 (en) 2020-11-20 2022-05-27 Simcere Innovation, Inc. Armed dual car-t compositions and methods for cancer immunotherapy
JP2022091709A (ja) * 2020-12-09 2022-06-21 株式会社ゲノム創薬研究所 サイトカインストーム治療・予防剤のスクリーニング方法及びサイトカインストーム治療・予防剤
US11969434B1 (en) 2022-08-29 2024-04-30 Lipocine Inc. Oral allopregnanolone compositions and methods of use
US12186327B2 (en) 2022-08-29 2025-01-07 Lipocine Inc. Oral allopregnanolone compositions and methods of use
WO2026092543A1 (en) * 2024-10-29 2026-05-07 Shenzhen Genocury Biotech Co., Ltd Methods and compositions of prophylactic therapy for preventing crs

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US20150290244A1 (en) * 2012-07-13 2015-10-15 The Trustees Of The University Of Pennsylvania Use of cart19 to deplete normal b cells to induce tolerance
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