CA3043732C - Methods of treating medical conditions by population based encoding of neural information - Google Patents

Methods of treating medical conditions by population based encoding of neural information Download PDF

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Publication number
CA3043732C
CA3043732C CA3043732A CA3043732A CA3043732C CA 3043732 C CA3043732 C CA 3043732C CA 3043732 A CA3043732 A CA 3043732A CA 3043732 A CA3043732 A CA 3043732A CA 3043732 C CA3043732 C CA 3043732C
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Prior art keywords
stimulation
sensation
patient
subject
electrode
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English (en)
French (fr)
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CA3043732A1 (en
Inventor
Daniel Tan
Matthew SCHIEFER
Dustin Tyler
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Case Western Reserve University
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Case Western Reserve University
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36003—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of motor muscles, e.g. for walking assistance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36031—Control systems using physiological parameters for adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36034—Control systems specified by the stimulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36067—Movement disorders, e.g. tremor or Parkinson disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/361—Phantom sensations, e.g. tinnitus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36103—Neuro-rehabilitation; Repair or reorganisation of neural tissue, e.g. after stroke
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A61N1/36139—Control systems using physiological parameters with automatic adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/3615—Intensity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36178—Burst or pulse train parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36189—Control systems using modulation techniques

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rehabilitation Therapy (AREA)
  • Hospice & Palliative Care (AREA)
  • Electrotherapy Devices (AREA)
  • Prostheses (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
CA3043732A 2012-12-14 2013-12-16 Methods of treating medical conditions by population based encoding of neural information Active CA3043732C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261737484P 2012-12-14 2012-12-14
US61/737484 2012-12-14
US201361774978P 2013-03-08 2013-03-08
US61/774978 2013-03-08
CA2988221A CA2988221C (en) 2012-12-14 2013-12-16 Methods of treating medical conditions by population based encoding of neural information

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2988221A Division CA2988221C (en) 2012-12-14 2013-12-16 Methods of treating medical conditions by population based encoding of neural information

Publications (2)

Publication Number Publication Date
CA3043732A1 CA3043732A1 (en) 2014-06-19
CA3043732C true CA3043732C (en) 2021-08-10

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Family Applications (3)

Application Number Title Priority Date Filing Date
CA3043732A Active CA3043732C (en) 2012-12-14 2013-12-16 Methods of treating medical conditions by population based encoding of neural information
CA2905042A Active CA2905042C (en) 2012-12-14 2013-12-16 METHODS FOR TREATING MEDICAL DISORDERS THROUGH CODING BASED ON A POPULATION OF NEURAL INFORMATION
CA2988221A Active CA2988221C (en) 2012-12-14 2013-12-16 Methods of treating medical conditions by population based encoding of neural information

Family Applications After (2)

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CA2905042A Active CA2905042C (en) 2012-12-14 2013-12-16 METHODS FOR TREATING MEDICAL DISORDERS THROUGH CODING BASED ON A POPULATION OF NEURAL INFORMATION
CA2988221A Active CA2988221C (en) 2012-12-14 2013-12-16 Methods of treating medical conditions by population based encoding of neural information

Country Status (6)

Country Link
US (8) US9421366B2 (cg-RX-API-DMAC7.html)
EP (2) EP2931361B1 (cg-RX-API-DMAC7.html)
JP (9) JP2016516450A (cg-RX-API-DMAC7.html)
AU (4) AU2013358920B2 (cg-RX-API-DMAC7.html)
CA (3) CA3043732C (cg-RX-API-DMAC7.html)
WO (1) WO2014093964A1 (cg-RX-API-DMAC7.html)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016516450A (ja) * 2012-12-14 2016-06-09 ケース ウェスタン リザーブ ユニバーシティＣａｓｅ Ｗｅｓｔｅｒｎ Ｒｅｓｅｒｖｅ Ｕｎｉｖｅｒｓｉｔｙ 神経情報の集団的符号化によって病状を治療する方法
CN105142714B (zh) 2013-01-21 2018-02-16 卡拉健康公司 用于控制震颤的设备和方法
US12453853B2 (en) 2013-01-21 2025-10-28 Cala Health, Inc. Multi-modal stimulation for treating tremor
EP3082946B1 (en) * 2013-12-16 2021-08-11 Case Western Reserve University Patterned stimulation intensity for neural stimulation
WO2015187712A1 (en) 2014-06-02 2015-12-10 Cala Health, Inc. Systems and methods for peripheral nerve stimulation to treat tremor
US9974959B2 (en) 2014-10-07 2018-05-22 Boston Scientific Neuromodulation Corporation Systems, devices, and methods for electrical stimulation using feedback to adjust stimulation parameters
EP4342516A3 (en) 2015-06-10 2024-07-10 Cala Health, Inc. Systems and methods for peripheral nerve stimulation to treat tremor with detachable therapy and monitoring units
US10603482B2 (en) 2015-09-23 2020-03-31 Cala Health, Inc. Systems and methods for peripheral nerve stimulation in the finger or hand to treat hand tremors
CN108778411B (zh) 2016-01-21 2022-06-03 卡拉健康公司 用来治疗与膀胱过动症相关的疾病的用于外周神经调制的系统、方法和装置
CN109803717B (zh) * 2016-08-25 2024-01-09 卡拉健康公司 通过周围神经刺激治疗心脏机能障碍的系统和方法
WO2018071494A1 (en) * 2016-10-12 2018-04-19 Case Western Reserve University Systems and methods for controlling levels of perceived intensity of a sensory stimulus
US11116974B2 (en) 2017-03-27 2021-09-14 Biotronik Se & Co. Kg Device and method for multi-modality spinal cord stimulation therapy
CA3058786A1 (en) 2017-04-03 2018-10-11 Cala Health, Inc. Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
US10751524B2 (en) * 2017-06-15 2020-08-25 Cochlear Limited Interference suppression in tissue-stimulating prostheses
EP3727566B1 (en) 2017-12-20 2024-08-28 Galvani Bioelectronics Limited Stimulation of a nerve supplying the spleen
EP3727570A1 (en) 2017-12-20 2020-10-28 Galvani Bioelectronics Limited Treatment of disorders associated with inflammation
JP2021507762A (ja) * 2017-12-20 2021-02-25 ガルバニ バイオエレクトロニクス リミテッド 急性疾患の治療
WO2019122906A1 (en) 2017-12-20 2019-06-27 Galvani Bioelectronics Limited Treatment of acute medical conditions
EP3740274A4 (en) 2018-01-17 2021-10-27 Cala Health, Inc. SYSTEMS AND METHODS FOR TREATING INFLAMMATORY INTESTINAL DISEASE USING PERIPHERAL NERVE STIMULATION
EP3773873B1 (en) 2018-03-27 2023-05-10 Boston Scientific Neuromodulation Corporation Hybrid sensing and stimulation utilizing pre-pulsing of waveforms
US12251560B1 (en) 2019-08-13 2025-03-18 Cala Health, Inc. Connection quality determination for wearable neurostimulation systems
US11446497B2 (en) 2019-08-20 2022-09-20 Case Western Reserve University Fatiguing a muscle to reduce onset response
US11890468B1 (en) 2019-10-03 2024-02-06 Cala Health, Inc. Neurostimulation systems with event pattern detection and classification
US12390646B2 (en) * 2020-12-02 2025-08-19 Inspire Medical Systems, Inc. Implantable medical devices
WO2022232036A1 (en) 2021-04-27 2022-11-03 Boston Scientific Neuromodulation Corporation Systems and methods for automated programming of electrical stimulation
US12403313B2 (en) 2021-06-15 2025-09-02 Boston Scientific Neuromodulation Corporation Methods and systems for estimating neural activation by stimulation using a stimulation system
EP4415809A2 (en) 2021-12-10 2024-08-21 Boston Scientific Neuromodulation Corporation Systems and methods for generating and using response maps for electrical stimulation
CN114652958B (zh) * 2022-02-24 2025-01-10 重庆大学 基于神经电刺激系统的替代型腕肘关节本体觉重建方法
US11833064B1 (en) 2022-06-03 2023-12-05 JSG IP Ventures, LLC System and methods for residual limbs of amputees
WO2023235849A1 (en) * 2022-06-03 2023-12-07 JSG IP Ventures, LLC System and methods for residual limbs of amputees
US11809629B1 (en) 2022-06-10 2023-11-07 Afference Inc. Wearable electronic device for inducing transient sensory events as user feedback
US12182328B2 (en) 2022-06-10 2024-12-31 Afference Inc. Wearable electronic device for inducing transient sensory events as user feedback
WO2024259387A1 (en) * 2023-06-16 2024-12-19 The University Of Chicago Spatiotemporally patterned multi-channel microstimulation of somatosensory cortex for improved resolution force feedback and perception of tactile motion and edge orientation
US12324754B1 (en) 2024-08-20 2025-06-10 JSG IP Ventures, LLC System for residual limbs of amputees
US12337177B1 (en) 2024-08-20 2025-06-24 JSG IP Ventures, LLC Method for residual limbs of amputees
US12329969B1 (en) 2024-08-20 2025-06-17 JSG IP Ventures, LLC System and methods for residual limbs of amputees
CN119680105B (zh) * 2025-02-21 2025-05-30 复远数科医疗(杭州)有限公司 神经源性膀胱治疗电刺激触觉评估方法、系统及穿戴设备

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52131677A (en) * 1976-04-26 1977-11-04 Kogyo Gijutsuin Information transmitting device by electric stimulation
US4340063A (en) * 1980-01-02 1982-07-20 Empi, Inc. Stimulation device
IL97701A (en) * 1991-03-28 1995-06-29 Univ Ben Gurion Device for desecrating the hand
JP3583777B2 (ja) * 1992-01-21 2004-11-04 エス・アール・アイ・インターナシヨナル テレオペレータシステムとテレプレゼンス法
US5397338A (en) 1993-03-29 1995-03-14 Maven Labs, Inc. Electrotherapy device
JP2001014082A (ja) * 1999-06-25 2001-01-19 Sentan Kagaku Gijutsu Incubation Center:Kk 神経インターフェイスシステム
DE60028773T2 (de) 1999-07-06 2007-06-14 Neurostream Technologies, Inc., Anmore Elektrisches stimulationssystem zur behandlung von phantomglierderschmerzen
US6937904B2 (en) * 2000-12-13 2005-08-30 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California System and method for providing recovery from muscle denervation
US7162303B2 (en) * 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
US20120303080A1 (en) 2003-06-13 2012-11-29 Bio Control Medical (B.C.M.) Ltd. Parasympathetic nerve stimulation
CA2876835C (en) 2003-06-24 2020-06-30 Medrelief Inc. Apparatus and method for bioelectric stimulation, healing acceleration, pain relief, or pathogen devitalization
US8165695B2 (en) * 2004-02-11 2012-04-24 Ethicon, Inc. System and method for selectively stimulating different body parts
US8024034B2 (en) * 2006-11-01 2011-09-20 Cardiac Pacemakers, Inc. Programmable neural therapies
US20090088659A1 (en) * 2007-09-27 2009-04-02 Immersion Corporation Biological Sensing With Haptic Feedback
US20090093856A1 (en) 2007-10-05 2009-04-09 Mady Attila High fidelity electronic tactile sensor and stimulator array, including sexual stimulus
FR2930139B1 (fr) * 2008-04-22 2022-12-30 Centre Nat Rech Scient Dispositif de reeducation fonctionnelle.
FR2935906B1 (fr) 2008-09-16 2011-03-11 I Gen Healthcare Ltd Dispositif de reeducation perineale.
JP2010162191A (ja) 2009-01-16 2010-07-29 Minato Ikagaku Kk 多チャンネル電気刺激装置
US8744588B2 (en) 2009-05-07 2014-06-03 Hani Midani Method and system for connecting an impaired nervous system to a muscle or a group of muscles based on template matching and intelligent end points
WO2011025771A1 (en) 2009-08-25 2011-03-03 Biogen Idec Ma Inc. Compositions for delivery of insoluble agents
AU2011239668B2 (en) 2010-04-15 2014-04-17 Cardiac Pacemakers, Inc. Autonomic modulation using transient response with intermittent neural stimulation
US20110270358A1 (en) 2010-04-30 2011-11-03 Medtronic, Inc. Implantable medical device programming using gesture-based control
US8788046B2 (en) * 2010-11-11 2014-07-22 Spr Therapeutics, Llc Systems and methods for the treatment of pain through neural fiber stimulation
EP3769811A1 (en) * 2011-01-25 2021-01-27 Apellis Holdings, LLC Apparatus and methods for assisting breathing
US20120197356A1 (en) 2011-01-27 2012-08-02 Medtronic, Inc. Waveforms for Remote Electrical Stimulation Therapy
BR112013018470B1 (pt) * 2011-01-28 2022-03-03 Micron Devices Llc Sistema de estimulador neural
CN107361741B (zh) 2011-03-24 2021-03-09 加利福尼亚理工学院 神经刺激器装置
JP2016516450A (ja) * 2012-12-14 2016-06-09 ケース ウェスタン リザーブ ユニバーシティＣａｓｅ Ｗｅｓｔｅｒｎ Ｒｅｓｅｒｖｅ Ｕｎｉｖｅｒｓｉｔｙ 神経情報の集団的符号化によって病状を治療する方法
US9174053B2 (en) 2013-03-08 2015-11-03 Boston Scientific Neuromodulation Corporation Neuromodulation using modulated pulse train
US9596224B2 (en) * 2013-04-05 2017-03-14 Nuvectra Corporation Systems, devices, components and methods for communicating with an IMD using a portable electronic device and a mobile computing device
EP3082946B1 (en) * 2013-12-16 2021-08-11 Case Western Reserve University Patterned stimulation intensity for neural stimulation
US9597507B2 (en) * 2014-10-31 2017-03-21 Medtronic, Inc. Paired stimulation pulses based on sensed compound action potential
US10698492B2 (en) 2017-09-28 2020-06-30 John James Daniels Wearable electronic, multi-sensory, human/machine, human/human interfaces

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AU2014366175B2 (en) 2017-04-13
CA2988221C (en) 2023-11-28
AU2017203309B2 (en) 2018-05-24
CA2905042C (en) 2025-10-07
US12144981B2 (en) 2024-11-19
US11446483B2 (en) 2022-09-20
CA3043732A1 (en) 2014-06-19
JP7540029B2 (ja) 2024-08-26
CA2988221A1 (en) 2014-06-19
JP2024127994A (ja) 2024-09-20
JP2016516450A (ja) 2016-06-09
JP2023078152A (ja) 2023-06-06
WO2014093964A1 (en) 2014-06-19
US20210069497A1 (en) 2021-03-11
AU2013358920B2 (en) 2016-05-19
US11612741B2 (en) 2023-03-28
US10960203B2 (en) 2021-03-30
EP4233993A3 (en) 2023-09-06
AU2017203309A1 (en) 2017-06-08
US20200391025A1 (en) 2020-12-17
US20150328465A1 (en) 2015-11-19
JP2018118098A (ja) 2018-08-02
AU2014366175A1 (en) 2016-07-07
EP2931361B1 (en) 2023-07-05
JP2019130320A (ja) 2019-08-08
JP2024174872A (ja) 2024-12-17
CA2905042A1 (en) 2014-06-19
JP6810179B2 (ja) 2021-01-06
US20250276173A1 (en) 2025-09-04
AU2013358920A1 (en) 2015-07-09
EP4233993A2 (en) 2023-08-30
JP2022107627A (ja) 2022-07-22
AU2018220123B2 (en) 2019-08-22
AU2018220123A1 (en) 2018-09-13
US9421366B2 (en) 2016-08-23
US20230310844A1 (en) 2023-10-05
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