CA3035931A1 - Cell expansion methods and therapeutic compositions - Google Patents

Cell expansion methods and therapeutic compositions Download PDF

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Publication number
CA3035931A1
CA3035931A1 CA3035931A CA3035931A CA3035931A1 CA 3035931 A1 CA3035931 A1 CA 3035931A1 CA 3035931 A CA3035931 A CA 3035931A CA 3035931 A CA3035931 A CA 3035931A CA 3035931 A1 CA3035931 A1 CA 3035931A1
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CA
Canada
Prior art keywords
mscs
cells
culture
media
conditioned media
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3035931A
Other languages
English (en)
French (fr)
Inventor
Balarka BANERJEE
Charlotte Morgan
Graham Vesey
Nicolle Hannah Packer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cell Ideas Pty Ltd
Original Assignee
Cell Ideas Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2015903658A external-priority patent/AU2015903658A0/en
Application filed by Cell Ideas Pty Ltd filed Critical Cell Ideas Pty Ltd
Publication of CA3035931A1 publication Critical patent/CA3035931A1/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0667Adipose-derived stem cells [ADSC]; Adipose stromal stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA3035931A 2015-09-08 2016-09-08 Cell expansion methods and therapeutic compositions Pending CA3035931A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2015903658A AU2015903658A0 (en) 2015-09-08 Cell expansion methods and therapeutic compositions
AU2015903658 2015-09-08
PCT/AU2016/000316 WO2017041133A1 (en) 2015-09-08 2016-09-08 Cell expansion methods and therapeutic compositions

Publications (1)

Publication Number Publication Date
CA3035931A1 true CA3035931A1 (en) 2017-03-16

Family

ID=58240422

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3035931A Pending CA3035931A1 (en) 2015-09-08 2016-09-08 Cell expansion methods and therapeutic compositions

Country Status (10)

Country Link
US (2) US20180236003A1 (cg-RX-API-DMAC7.html)
EP (1) EP3347449A4 (cg-RX-API-DMAC7.html)
JP (3) JP6995752B2 (cg-RX-API-DMAC7.html)
KR (1) KR20180043834A (cg-RX-API-DMAC7.html)
CN (1) CN108348555B (cg-RX-API-DMAC7.html)
AU (1) AU2016321448B2 (cg-RX-API-DMAC7.html)
CA (1) CA3035931A1 (cg-RX-API-DMAC7.html)
HK (1) HK1252778A1 (cg-RX-API-DMAC7.html)
TW (1) TWI760313B (cg-RX-API-DMAC7.html)
WO (1) WO2017041133A1 (cg-RX-API-DMAC7.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3365432T1 (sl) * 2015-10-23 2020-08-31 Rigshospitalet Terapija z matičnimi celicami, na osnovi matičnih celic iz adipoze
EP3624731A4 (en) * 2017-05-18 2021-02-24 The Board of Trustees of the Leland Stanford Junior University TARGETED IN-SITU THERAPEUTIC ADMINISTRATION OF SECRETED FACTORS FROM STEM CELLS FOR THE TREATMENT OF DAMAGED TISSUE
EP3806872A1 (en) 2018-06-15 2021-04-21 Mariñas Pardo, Luis Pharmaceutical composition for dermatology and uses thereof
CN109022360A (zh) * 2018-07-03 2018-12-18 湖南未名三胞转化医学科技有限公司 自体脂肪干细胞共培养促进外周血造血干细胞增殖方法
CN110106142B (zh) * 2019-05-30 2020-05-12 深圳阿尔法生物科技有限公司 一种制备“百亿”级脂肪源再生细胞的生产工艺
CN111073857A (zh) * 2019-12-30 2020-04-28 深圳爱生再生医学科技有限公司 一种治疗关节炎的干细胞生物制品及其制备方法与应用
KR102193175B1 (ko) * 2020-04-07 2020-12-18 주식회사 엑소스템텍 통증조절인자를 함유한 줄기세포유래 엑소좀 및 그 용도
CO2020012570A1 (es) 2020-10-08 2022-04-08 Inst Distrital De Ciencia Biotecnologia E Innovacion En Salud Idcbis Método de estimulación de células mesenquimales para inducir expresión de factores inmunomoduladores
WO2022091086A1 (en) * 2020-10-26 2022-05-05 Hadasit Medical Research Services And Development Ltd. Mesenchymal stem cells and their culture
BR102022016233A2 (pt) * 2022-08-16 2024-02-27 Omics Biotecnologia Animal Ltda Concentrado de proteínas e peptídeos derivados de células estromais mesenquimais, método de obtenção e uso de concentrado

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0404656D0 (en) * 2004-03-02 2004-04-07 Univ Manchester Treatment of spinal conditions
EP2069479A1 (en) * 2006-09-18 2009-06-17 Medizinische Universität Graz Plasma-free platelet lysate for use as a supplement in cell cultures and for the preparation of cell therapeutics
CN103180435A (zh) * 2010-08-31 2013-06-26 库克通用生物技术有限责任公司 用于治疗动物疾病的全身的同种异体干细胞疗法
WO2013040649A1 (en) 2011-09-23 2013-03-28 Cell Ideas Pty Ltd Therapeutics using adipose cells and cell secretions
US20140219972A1 (en) * 2013-02-05 2014-08-07 The Board Of Trustees Of The Leland Stanford Junior University Tissue engineering using progenitor cells to catalyze tissue formation by primary cells
ES3042057T3 (en) * 2016-08-26 2025-11-18 Restem Llc Composition and methods of using umbilical cord lining stem cells

Also Published As

Publication number Publication date
TWI760313B (zh) 2022-04-11
HK1252778A1 (zh) 2019-05-31
CN108348555B (zh) 2022-07-08
JP6995752B2 (ja) 2022-02-04
AU2016321448A1 (en) 2018-03-15
JP2022027928A (ja) 2022-02-14
CN108348555A (zh) 2018-07-31
TW201720922A (zh) 2017-06-16
EP3347449A4 (en) 2019-03-20
JP2022186992A (ja) 2022-12-15
WO2017041133A1 (en) 2017-03-16
US20210260129A1 (en) 2021-08-26
AU2016321448B2 (en) 2023-02-02
US20180236003A1 (en) 2018-08-23
JP2018526447A (ja) 2018-09-13
KR20180043834A (ko) 2018-04-30
EP3347449A1 (en) 2018-07-18

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