CA3012463A1 - Method and systems for analyzing functional imaging data - Google Patents

Method and systems for analyzing functional imaging data Download PDF

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Publication number
CA3012463A1
CA3012463A1 CA3012463A CA3012463A CA3012463A1 CA 3012463 A1 CA3012463 A1 CA 3012463A1 CA 3012463 A CA3012463 A CA 3012463A CA 3012463 A CA3012463 A CA 3012463A CA 3012463 A1 CA3012463 A1 CA 3012463A1
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Prior art keywords
neuronal
brain
functional activity
connectivity
msn
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CA3012463A
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English (en)
French (fr)
Inventor
Jin Hyung Lee
David BERNAL-CASAS
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Leland Stanford Junior University
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Leland Stanford Junior University
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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/242—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents
    • A61B5/245—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents specially adapted for magnetoencephalographic [MEG] signals
    • A61B5/246—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents specially adapted for magnetoencephalographic [MEG] signals using evoked responses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064—Evaluating the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7275—Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0622—Optical stimulation for exciting neural tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4806—Functional imaging of brain activation
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
    • G16Z99/00—Subject matter not provided for in other main groups of this subclass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2576/00—Medical imaging apparatus involving image processing or analysis
    • A61B2576/02—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part
    • A61B2576/026—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part for the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/242—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents
    • A61B5/245—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents specially adapted for magnetoencephalographic [MEG] signals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Neurosurgery (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Physiology (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • General Physics & Mathematics (AREA)
  • Psychology (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Psychiatry (AREA)
  • Artificial Intelligence (AREA)
  • Signal Processing (AREA)
  • Theoretical Computer Science (AREA)
  • Quality & Reliability (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
CA3012463A 2016-02-01 2017-01-30 Method and systems for analyzing functional imaging data Pending CA3012463A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662289741P 2016-02-01 2016-02-01
US62/289,741 2016-02-01
PCT/US2017/015659 WO2017136285A1 (en) 2016-02-01 2017-01-30 Method and systems for analyzing functional imaging data

Publications (1)

Publication Number Publication Date
CA3012463A1 true CA3012463A1 (en) 2017-08-10

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA3012463A Pending CA3012463A1 (en) 2016-02-01 2017-01-30 Method and systems for analyzing functional imaging data

Country Status (6)

Country Link
US (1) US11564615B2 (https=)
EP (1) EP3410926A4 (https=)
JP (1) JP6987062B2 (https=)
KR (1) KR102855002B1 (https=)
CA (1) CA3012463A1 (https=)
WO (1) WO2017136285A1 (https=)

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CN112839577A (zh) * 2018-10-11 2021-05-25 株式会社国际电气通信基础技术研究所 脑功能连接相关值的调整方法、脑功能连接相关值的调整系统、脑活动分类器的协调方法、脑活动分类器的协调系统以及脑活动生物标记物系统
US11420071B2 (en) 2017-04-11 2022-08-23 Peaklogic, Inc. Minimum neuronal activation threshold transcranial magnetic stimulation at personalized resonant frequency

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GB201702600D0 (en) * 2017-02-17 2017-04-05 Biomax Informatics Ag Neurological data processing
EP3706617B1 (en) * 2017-11-10 2025-01-29 LVIS Corporation Efficacy and/or therapeutic parameter recommendation using individual patient data and therapeutic brain network maps
US11227692B2 (en) * 2017-12-28 2022-01-18 International Business Machines Corporation Neuron model simulation
KR102058625B1 (ko) 2018-01-12 2019-12-23 서울대학교병원 뇌 기능 연결성 분석을 이용한 어지럼증 진단 방법 및 이를 적용하는 시스템
WO2019191311A1 (en) * 2018-03-28 2019-10-03 Icahn School Of Medicine At Mount Sinai Systems and methods for processing connectivity values between sub-processing regions
WO2020005525A1 (en) * 2018-06-26 2020-01-02 University Of Southern California Methods and analytical tools for the study and treatment of epileptogenesis
EP3830595A1 (en) 2018-07-30 2021-06-09 Koninklijke Philips N.V. Functional magnetic resonance imaging systems and methods
CN109528197B (zh) * 2018-11-20 2022-07-08 中国科学院脑科学与智能技术卓越创新中心 基于脑功能图谱进行精神疾病的个体化预测方法和系统
US12507893B2 (en) * 2019-02-08 2025-12-30 Shimadzu Corporation Brain function measurement device
WO2020241772A1 (ja) 2019-05-31 2020-12-03 国立大学法人京都大学 情報処理装置、スクリーニング装置、情報処理方法、スクリーニング方法、及びプログラム
JP7678577B2 (ja) * 2019-05-31 2025-05-16 国立大学法人京都大学 情報処理装置、情報処理方法、及びプログラム
WO2021051064A1 (en) * 2019-09-12 2021-03-18 The General Hospital Corporation System and method for determining treatment outcomes for neurological disorders based on functional connectivity parameters
KR102951752B1 (ko) * 2019-09-25 2026-04-14 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 안와전두 피질에 대한 시상 입력은 gaba 및 불확대에 의해 매개된 광범한 뇌, 주파수-의존적 억제를 유도한다
KR102949868B1 (ko) * 2019-10-01 2026-04-08 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 다중 스케일 뇌 네트워크 기능 모델링을 가능하게 하기 위한 공동 동적 인과 모델링 및 생물 물리학 모델링
IL293445A (en) * 2019-12-06 2022-07-01 Univ Leland Stanford Junior Simulating single hippocampal seizures and the long-term effect of repeated seizures
US20210170180A1 (en) * 2019-12-09 2021-06-10 Washington University Systems and methods of precision functional mapping-guided personalized neuromodulation
US20230104356A1 (en) * 2020-03-27 2023-04-06 Tata Consultancy Services Limited Model driven sub-system for design and execution of experiments
US11037296B1 (en) * 2020-08-07 2021-06-15 Omniscient Neurotechnology Pty Limited Deriving target data from selected brain data
JP2022006151A (ja) * 2020-09-01 2022-01-12 昇 松本 デジタル神経細胞情報処理装置。
US11264137B1 (en) 2020-10-08 2022-03-01 Omniscient Neurotechnology Pty Limited Centrality rankings of network graphs generated using connectomic brain data
US11264138B1 (en) * 2020-10-08 2022-03-01 Omniscient Neurotechnology Pty Limited Generating brain network impact scores
WO2022125811A1 (en) * 2020-12-10 2022-06-16 Beth Israel Deaconess Medical Center, Inc. Targeting transcranial magnetic stimulation to specific brain regions and evaluating the reduction of symptoms of psychotic disorders
US11699232B2 (en) * 2021-09-01 2023-07-11 Omniscient Neurotechnology Pty Limited Brain hub explorer
US20250242167A1 (en) * 2022-04-11 2025-07-31 Regents Of The University Of Minnesota Closed-loop neurostimulation using global optimization-based temporal prediction
WO2024073593A2 (en) * 2022-09-30 2024-04-04 The Board Of Trustees Of The Leland Stanford Junior University Solving brain circuit function and dysfunction with computational modeling and optogenetic functional magnetic resonance imaging
WO2025054159A1 (en) * 2023-09-05 2025-03-13 University Of Louisville Research Foundation, Inc. Computed-aided system for diagnosis of neurological disorders
CN118155855B (zh) * 2024-03-14 2024-09-13 武汉市精神卫生中心 基于磁共振成像观测的双相障碍神经动力学演化分析方法
CN120267969B (zh) * 2025-02-17 2025-11-25 江苏脑意科技有限公司 基于电刺激的神经调控方法、装置、设备及存储介质

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KR102893860B1 (ko) 2015-12-09 2025-12-03 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 기능적 뇌 회로 분석법
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11420071B2 (en) 2017-04-11 2022-08-23 Peaklogic, Inc. Minimum neuronal activation threshold transcranial magnetic stimulation at personalized resonant frequency
US12343551B2 (en) 2017-04-11 2025-07-01 Peaklogic, Inc. Minimum neuronal activation threshold transcranial magnetic stimulation at personalized resonant frequency
CN112839577A (zh) * 2018-10-11 2021-05-25 株式会社国际电气通信基础技术研究所 脑功能连接相关值的调整方法、脑功能连接相关值的调整系统、脑活动分类器的协调方法、脑活动分类器的协调系统以及脑活动生物标记物系统
CN112839577B (zh) * 2018-10-11 2024-07-23 株式会社国际电气通信基础技术研究所 脑功能连接相关值的调整方法、脑功能连接相关值的调整系统、脑活动分类器的协调方法、脑活动分类器的协调系统以及脑活动生物标记物系统

Also Published As

Publication number Publication date
US20180368720A1 (en) 2018-12-27
EP3410926A4 (en) 2019-08-28
KR20180107224A (ko) 2018-10-01
WO2017136285A1 (en) 2017-08-10
JP2019508109A (ja) 2019-03-28
JP6987062B2 (ja) 2021-12-22
US11564615B2 (en) 2023-01-31
EP3410926A1 (en) 2018-12-12
KR102855002B1 (ko) 2025-09-04

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