CA3012463A1 - Method and systems for analyzing functional imaging data - Google Patents

Method and systems for analyzing functional imaging data Download PDF

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Publication number
CA3012463A1
CA3012463A1 CA3012463A CA3012463A CA3012463A1 CA 3012463 A1 CA3012463 A1 CA 3012463A1 CA 3012463 A CA3012463 A CA 3012463A CA 3012463 A CA3012463 A CA 3012463A CA 3012463 A1 CA3012463 A1 CA 3012463A1
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Prior art keywords
neuronal
brain
functional activity
connectivity
msn
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CA3012463A
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English (en)
French (fr)
Inventor
Jin Hyung Lee
David BERNAL-CASAS
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Leland Stanford Junior University
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Leland Stanford Junior University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7275—Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/242—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents
    • A61B5/245—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents specially adapted for magnetoencephalographic [MEG] signals
    • A61B5/246—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents specially adapted for magnetoencephalographic [MEG] signals using evoked responses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/369—Electroencephalography [EEG]
    • A61B5/377—Electroencephalography [EEG] using evoked responses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064—Evaluating the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0622—Optical stimulation for exciting neural tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4806—Functional imaging of brain activation
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
    • G16Z99/00—Subject matter not provided for in other main groups of this subclass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2576/00—Medical imaging apparatus involving image processing or analysis
    • A61B2576/02—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part
    • A61B2576/026—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part for the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/242—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents
    • A61B5/245—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents specially adapted for magnetoencephalographic [MEG] signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/369—Electroencephalography [EEG]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Neurosurgery (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Psychology (AREA)
  • Physiology (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • General Physics & Mathematics (AREA)
  • Psychiatry (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Signal Processing (AREA)
  • Artificial Intelligence (AREA)
  • Quality & Reliability (AREA)
  • Theoretical Computer Science (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
CA3012463A 2016-02-01 2017-01-30 Method and systems for analyzing functional imaging data Pending CA3012463A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662289741P 2016-02-01 2016-02-01
US62/289,741 2016-02-01
PCT/US2017/015659 WO2017136285A1 (en) 2016-02-01 2017-01-30 Method and systems for analyzing functional imaging data

Publications (1)

Publication Number Publication Date
CA3012463A1 true CA3012463A1 (en) 2017-08-10

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CA3012463A Pending CA3012463A1 (en) 2016-02-01 2017-01-30 Method and systems for analyzing functional imaging data

Country Status (6)

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US (1) US11564615B2 (enExample)
EP (1) EP3410926A4 (enExample)
JP (1) JP6987062B2 (enExample)
KR (1) KR102855002B1 (enExample)
CA (1) CA3012463A1 (enExample)
WO (1) WO2017136285A1 (enExample)

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CN112839577A (zh) * 2018-10-11 2021-05-25 株式会社国际电气通信基础技术研究所 脑功能连接相关值的调整方法、脑功能连接相关值的调整系统、脑活动分类器的协调方法、脑活动分类器的协调系统以及脑活动生物标记物系统
US11420071B2 (en) 2017-04-11 2022-08-23 Peaklogic, Inc. Minimum neuronal activation threshold transcranial magnetic stimulation at personalized resonant frequency

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US11227692B2 (en) * 2017-12-28 2022-01-18 International Business Machines Corporation Neuron model simulation
KR102058625B1 (ko) 2018-01-12 2019-12-23 서울대학교병원 뇌 기능 연결성 분석을 이용한 어지럼증 진단 방법 및 이를 적용하는 시스템
ES3042164T3 (en) * 2018-03-28 2025-11-18 Icahn School Med Mount Sinai Systems and methods for processing connectivity values between sub-processing regions
WO2020005525A1 (en) * 2018-06-26 2020-01-02 University Of Southern California Methods and analytical tools for the study and treatment of epileptogenesis
JP2021531891A (ja) 2018-07-30 2021-11-25 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. 機能的磁気共鳴イメージングシステム及び方法
CN109528197B (zh) * 2018-11-20 2022-07-08 中国科学院脑科学与智能技术卓越创新中心 基于脑功能图谱进行精神疾病的个体化预测方法和系统
JP7367707B2 (ja) * 2019-02-08 2023-10-24 株式会社島津製作所 脳機能計測装置
WO2020241772A1 (ja) 2019-05-31 2020-12-03 国立大学法人京都大学 情報処理装置、スクリーニング装置、情報処理方法、スクリーニング方法、及びプログラム
SG11202113100TA (en) * 2019-05-31 2021-12-30 Univ Kyoto Information processing device, screening device, information processing method, screening method, and program
US20220313144A1 (en) * 2019-09-12 2022-10-06 The General Hospital Corporation System amd method for determining treatment outcomes for neurological disorders based on functional connectivity parameters
US20220401751A1 (en) * 2019-09-25 2022-12-22 The Board Of Trustees Of The Leland Stanford Junior University Thalamic Input to Orbitofrontal Cortex Drives Brain-Wide, Frequency-Dependent Inhibition Mediated By GABA and Zona Incerta
JP7641953B2 (ja) * 2019-10-01 2025-03-07 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー マルチスケール脳ネットワーク機能のモデル化を可能にする合同の動的因果モデル化と生物物理学的モデル化
CN115023177A (zh) * 2019-12-06 2022-09-06 小利兰·斯坦福大学托管委员会 对个体海马癫痫发作进行成像以及反复癫痫发作的长期影响
US11733332B2 (en) * 2019-12-09 2023-08-22 Nous Imaging, Inc. Systems and method of precision functional mapping-guided interventional planning
US20230104356A1 (en) * 2020-03-27 2023-04-06 Tata Consultancy Services Limited Model driven sub-system for design and execution of experiments
US11037296B1 (en) 2020-08-07 2021-06-15 Omniscient Neurotechnology Pty Limited Deriving target data from selected brain data
JP2022006151A (ja) * 2020-09-01 2022-01-12 昇 松本 デジタル神経細胞情報処理装置。
US11264137B1 (en) 2020-10-08 2022-03-01 Omniscient Neurotechnology Pty Limited Centrality rankings of network graphs generated using connectomic brain data
US11264138B1 (en) * 2020-10-08 2022-03-01 Omniscient Neurotechnology Pty Limited Generating brain network impact scores
US20240075310A1 (en) * 2020-12-10 2024-03-07 Beth Israel Deaconess Medical Center, Inc. Targeting Trancranial Magnetic Stimulation to Specific Brain Regions and Evaluating the Reduction of Symptoms of Psychotic Disorders
US11699232B2 (en) * 2021-09-01 2023-07-11 Omniscient Neurotechnology Pty Limited Brain hub explorer
US20250242167A1 (en) * 2022-04-11 2025-07-31 Regents Of The University Of Minnesota Closed-loop neurostimulation using global optimization-based temporal prediction
CA3269322A1 (en) * 2022-09-30 2024-04-04 Univ Leland Stanford Junior RESOLUTION OF BRAIN CIRCUIT FUNCTION AND DYSFUNCTION WITH COMPUTER MODELING AND OPTOGENIC FUNCTIONAL MAGNETIC RESONANCE IMAGING
WO2025054159A1 (en) * 2023-09-05 2025-03-13 University Of Louisville Research Foundation, Inc. Computed-aided system for diagnosis of neurological disorders
CN118155855B (zh) * 2024-03-14 2024-09-13 武汉市精神卫生中心 基于磁共振成像观测的双相障碍神经动力学演化分析方法
CN120267969B (zh) * 2025-02-17 2025-11-25 江苏脑意科技有限公司 基于电刺激的神经调控方法、装置、设备及存储介质

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11420071B2 (en) 2017-04-11 2022-08-23 Peaklogic, Inc. Minimum neuronal activation threshold transcranial magnetic stimulation at personalized resonant frequency
US12343551B2 (en) 2017-04-11 2025-07-01 Peaklogic, Inc. Minimum neuronal activation threshold transcranial magnetic stimulation at personalized resonant frequency
CN112839577A (zh) * 2018-10-11 2021-05-25 株式会社国际电气通信基础技术研究所 脑功能连接相关值的调整方法、脑功能连接相关值的调整系统、脑活动分类器的协调方法、脑活动分类器的协调系统以及脑活动生物标记物系统
CN112839577B (zh) * 2018-10-11 2024-07-23 株式会社国际电气通信基础技术研究所 脑功能连接相关值的调整方法、脑功能连接相关值的调整系统、脑活动分类器的协调方法、脑活动分类器的协调系统以及脑活动生物标记物系统

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KR20180107224A (ko) 2018-10-01
US20180368720A1 (en) 2018-12-27
US11564615B2 (en) 2023-01-31
EP3410926A4 (en) 2019-08-28
WO2017136285A1 (en) 2017-08-10
EP3410926A1 (en) 2018-12-12
JP2019508109A (ja) 2019-03-28
JP6987062B2 (ja) 2021-12-22
KR102855002B1 (ko) 2025-09-04

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