CA3008033A1 - Method and composition for increasing muscle protein synthesis and/or functional strength in mammals - Google Patents

Method and composition for increasing muscle protein synthesis and/or functional strength in mammals Download PDF

Info

Publication number
CA3008033A1
CA3008033A1 CA3008033A CA3008033A CA3008033A1 CA 3008033 A1 CA3008033 A1 CA 3008033A1 CA 3008033 A CA3008033 A CA 3008033A CA 3008033 A CA3008033 A CA 3008033A CA 3008033 A1 CA3008033 A1 CA 3008033A1
Authority
CA
Canada
Prior art keywords
composition
week
protein
amino acid
protein building
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3008033A
Other languages
English (en)
French (fr)
Inventor
Aouatef Bellamine
Ilya ZHIVKOVICH
Ulla Freitas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza Greenwood LLC
Original Assignee
Lonza LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza LLC filed Critical Lonza LLC
Publication of CA3008033A1 publication Critical patent/CA3008033A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/30Oligoelements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52Adding ingredients
    • A23L2/66Proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16Inorganic salts, minerals or trace elements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/152Milk preparations; Milk powder or milk powder preparations containing additives
    • A23C9/1526Amino acids; Peptides; Protein hydrolysates; Nucleic acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Non-Alcoholic Beverages (AREA)
  • Fodder In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Physiology (AREA)
CA3008033A 2015-12-18 2016-12-16 Method and composition for increasing muscle protein synthesis and/or functional strength in mammals Pending CA3008033A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562269573P 2015-12-18 2015-12-18
US62/269,573 2015-12-18
US201562273880P 2015-12-31 2015-12-31
US62/273,880 2015-12-31
PCT/US2016/067238 WO2017106687A1 (en) 2015-12-18 2016-12-16 Method and composition for increasing muscle protein synthesis and/or functional strength in mammals as well as method of producing a composition

Publications (1)

Publication Number Publication Date
CA3008033A1 true CA3008033A1 (en) 2017-06-22

Family

ID=57910110

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3008033A Pending CA3008033A1 (en) 2015-12-18 2016-12-16 Method and composition for increasing muscle protein synthesis and/or functional strength in mammals

Country Status (6)

Country Link
US (2) US10888571B2 (enExample)
EP (1) EP3389385A1 (enExample)
JP (2) JP2018537987A (enExample)
BR (1) BR112018012410B1 (enExample)
CA (1) CA3008033A1 (enExample)
WO (1) WO2017106687A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3008033A1 (en) * 2015-12-18 2017-06-22 Lonza, Inc. Method and composition for increasing muscle protein synthesis and/or functional strength in mammals
CN118178404A (zh) * 2017-11-02 2024-06-14 生物风险投资有限责任公司 氨基酸补充剂在提高肌肉蛋白质合成中的用途
KR102853179B1 (ko) * 2019-03-06 2025-08-29 시엔펑 펑 동물사료 첨가제를 제조하기 위한 γ-4차 암모늄 부티레이트계 화합물의 용도
EP4027990A4 (en) * 2019-10-16 2023-10-18 Capsugel Belgium NV METHOD AND COMPOSITION FOR INCREASE SYNTHESIS OF MUSCLE PROTEIN
MX2022004515A (es) * 2019-10-16 2022-07-12 Capsugel Belgium Nv Metodo y composicion para aumentar la sintesis de proteinas musculares.
DE102022114966A1 (de) 2022-06-14 2023-12-14 Alzchem Trostberg Gmbh Wasserlösliches Kreatin-Agglomerat

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4687782A (en) 1984-12-10 1987-08-18 Nutri-Fuels Systems, Inc. Nutritional composition for enhancing skeletal muscle adaptation to exercise training
US4883672A (en) 1988-04-29 1989-11-28 Shug Austin L Method for preventing diet induced carnitine deficiency in domesticated dogs and cats
AU3086897A (en) * 1996-06-28 1998-01-21 Ipr-Institute For Pharmaceutical Research Ag Drug preparations, containing creatine with at least one salt of calcium, magnesium, manganese or zinc
US6232346B1 (en) * 1997-03-27 2001-05-15 Michael J. Sole Composition for improvement of cellular nutrition and mitochondrial energetics
IT1291127B1 (it) * 1997-04-01 1998-12-29 Sigma Tau Ind Farmaceuti Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica
US6159942A (en) 1998-06-19 2000-12-12 Bioenergy, Inc. Compositions for increasing energy in vivo
IT1306173B1 (it) 1999-07-23 2001-05-30 Sigma Tau Healthscience Spa Composizione per la prevenzione degli affaticamenti muscolari e permigliorare il rendimento energetico muscolare.
CA2399319A1 (en) 2000-01-25 2001-08-16 Nathan D. Hamilton Nutritional supplements for aged pets
US20030138547A1 (en) 2002-01-22 2003-07-24 Mars, Incorporated Weight management system for animals
AU2005322015B2 (en) 2004-12-29 2010-02-25 Hill's Pet Nutrition, Inc. Methods for inhibiting a decline in learning and/or memory in animals
US7645742B2 (en) * 2005-06-22 2010-01-12 Advocare International, L.P. Composition for enhancing cellular energy
US20080085343A1 (en) * 2006-09-14 2008-04-10 Petty Holly T Novel Low Allergenic Food Bar
WO2008115563A1 (en) * 2007-03-19 2008-09-25 University Of Florida Research Foundation, Inc. Liquid nutrient composition for improving performance
US7790688B2 (en) * 2008-01-11 2010-09-07 Healthspan Solutions, Llc Compositions and methods for increasing muscle mass, strength, and functional performance in the elderly
US8546369B2 (en) 2008-05-30 2013-10-01 Northern Innovations Holding Corp. Salts of creatine imino sugar amides
FR2938733A1 (fr) 2008-11-21 2010-05-28 Holymark Composition administrable par voie orale,en particulier pour personne pratiquant une activite physique et complement alimentaire renfermant une telle composition
US8784844B2 (en) 2009-09-30 2014-07-22 Lonza Ltd. Arabinogalactan for enhancing the adaptive immune response
CA2835429A1 (en) 2011-05-10 2012-11-15 Nestec S.A. Methods and compositions for promoting lean body mass growth
ITTO20121098A1 (it) 2012-12-18 2014-06-19 Univ Degli Studi Genova Procedimento per sintetizzare derivati della creatina
WO2015094772A1 (en) 2013-12-18 2015-06-25 Abbott Laboratories Methods for increasing skeletal muscle protein synthesis using green tea extract
CA2951567C (en) 2014-06-12 2023-10-31 Lonza, Inc. Method for decreasing skeletal muscle damage and/or oxidative stress in mammals
CA3008033A1 (en) * 2015-12-18 2017-06-22 Lonza, Inc. Method and composition for increasing muscle protein synthesis and/or functional strength in mammals

Also Published As

Publication number Publication date
WO2017106687A1 (en) 2017-06-22
BR112018012410B1 (pt) 2022-12-20
JP2018537987A (ja) 2018-12-27
BR112018012410A2 (en) 2018-12-04
US20170173050A1 (en) 2017-06-22
US20210205334A1 (en) 2021-07-08
US10888571B2 (en) 2021-01-12
EP3389385A1 (en) 2018-10-24
JP2022064912A (ja) 2022-04-26

Similar Documents

Publication Publication Date Title
US20210205334A1 (en) Methods and Composition for Increasing Muscle Protein Synthesis and/or Functional Strength in Mammals
JP6255079B2 (ja) シトルリンおよびアルギニンを含有する即効性血中アルギニン濃度上昇型経口剤
JP7266581B2 (ja) 肝疾患の治療のためのアミノ酸組成物
US20080268038A1 (en) Compositions and Approaches for Increasing Diet Induced Thermogenesis, Inducing Weight Loss and Maintaining Muscle Mass and Strength
US20040043442A1 (en) Use of betaine in functional products having blood pressure lowering effects
US12403123B2 (en) Method for treating sickle cell disease using quercetin-containing compositions
US11752112B2 (en) Composition for stimulating muscle growth, repair, and maintenance
JP7761231B2 (ja) 血圧降下のためのchp(シクロ-ヒスプロ)の用途
JP5922862B2 (ja) ミトコンドリア機能向上剤
JPWO2008136173A1 (ja) スチルベン誘導体を有効成分とする脂肪細胞分化抑制剤
RU2335927C2 (ru) Обогащенные лейцином питательные композиции
JP2003511097A (ja) 栄養補助剤
EP3855944A1 (en) Method and composition for increasing the bioavailability of carnitine
WO2018085440A1 (en) Reduction and prevention of muscle loss by conjugated linoleic acid (cla) and vitamin d
WO2020018911A1 (en) Nutritional compositions for enhancement of muscle performance

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20211201

EEER Examination request

Effective date: 20211201

EEER Examination request

Effective date: 20211201

EEER Examination request

Effective date: 20211201

EEER Examination request

Effective date: 20211201

EEER Examination request

Effective date: 20211201

EEER Examination request

Effective date: 20211201

EEER Examination request

Effective date: 20211201

EEER Examination request

Effective date: 20211201

EEER Examination request

Effective date: 20211201

EEER Examination request

Effective date: 20211201